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RESEARCH PRODUCT

Could Chronic Idiopatic Intestinal Pseudo-Obstruction Be Related to Viral Infections?

Rita AlloroSocrate PallioDario RaimondoEmanuele SinagraGiuseppe ConoscentiFrancesca RossiGaia PellegattaAndrea AnderloniMarcello Maida

subject

Intestinal pseudo-obstructionmedicine.medical_specialtyviruseslcsh:MedicineReviewvirusDiseasemedicine.disease_causeGastroenterologyHerpesviridaeVirusPathogenesis03 medical and health sciences0302 clinical medicineInternal medicinemedicinebusiness.industrylcsh:Rgastrointestinal motility disordersGeneral Medicinemedicine.diseasePathophysiologyBowel obstructionchronic idiopathic intestinal pseudo-obstruction030220 oncology & carcinogenesisEtiology030211 gastroenterology & hepatologybusiness

description

Chronic idiopathic intestinal pseudo-obstruction (CIIPO) is a disease characterized by symptoms and signs of small bowel obstruction in the absence of displayable mechanical obstruction. Due to the known neuropathic capacity of several viruses, and their localization in the intestine, it has been hypothesized that such viruses could be involved in the pathogenesis of CIIPO. The most frequently involved viruses are John Cunningham virus, Herpesviridae, Flaviviruses, Epstein–Barr virus and Citomegalovirus. Therefore, the present narrative review aims to sum up some new perspectives in the etiology and pathophysiology of CIIPO.

https://doi.org/10.3390/jcm10020268