6533b872fe1ef96bd12d407e

RESEARCH PRODUCT

Human Thyroid Cancer Stem Cells

Antonina BenfanteVeronica CatalanoGiorgio StassiMatilde Todaro

subject

Oncologymedicine.medical_specialtyDiagnostic methodsbusiness.industryThyroidmedicine.diseasemedicine.disease_causemedicine.anatomical_structureCancer stem cellInternal medicineCellular aspectsmedicineCancer researchHuman thyroidStem cellCarcinogenesisbusinessThyroid cancer

description

Increasing advances in stem cell research have opened new chances for treatment of many types of cancers. The identification of Cancer Stem Cells (CSCs) will provide a better knowledge of the molecular events governing carcinogenesis and the establishment of more accurate diagnostic methods and effective therapies. Parallel to other tumors, it has been demonstrated the presence of CSCs in thyroid cancers. Here, we will discuss the origin of human thyroid cancer stem cells and what is known about the molecular and the cellular aspects of their biology. We will also explore the potential traits of CSCs in thyroid cancer which give hope for the development of new therapeutic approaches in treatment-resistant thyroid cancer.

yearjournalcountryeditionlanguage
2011-09-06
https://doi.org/10.1007/978-94-007-2016-9_15