6533b872fe1ef96bd12d41d0
RESEARCH PRODUCT
1H-, 13C-, and 15N-NMR and ESI-TOF+ MS studies of a supramolecular complex of silver(I) and a cholaphane
Pia MänttäriElina VirtanenJuha KoivukorpiErkki KolehmainenJari Tamminensubject
Lithocholic acidLigandOrganic ChemistryInorganic chemistrySupramolecular chemistryBiochemistryCombinatorial chemistryIonInorganic Chemistrychemistry.chemical_compoundPiperazinechemistryTransition metalMaterials ChemistryThiopheneMoleculePhysical and Theoretical Chemistrydescription
A novel application of the mixed anhydride procedure for synthesising lithocholic acid piperazine diamide, an important intermediate in designing bile acid-based supramolecular host molecules, is reported. The synthesis of a thiophene-containing cholaphane with transition metal complexation ability and 1H-, 13C-, and 15N-NMR as well as ESI-TOF+ MS spectral characterisation of the ligand and its Ag(I) complex are included. The coordination of the Ag(I) ion as well as an ability of the cholaphane to recognise Ag(I) ion over alkali metal ions, especially potassium ion, is discussed. The possible medical applications are also presented.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2003-02-01 | Journal of Organometallic Chemistry |