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RESEARCH PRODUCT

Type 1 or Type 2 Myocardial Infarction in Patients with a History of Coronary Artery Disease: Data from the Emergency Department

Patrick RayPatrick ManckoundiaFrédéric ChaguéAurélie AvondoYves CottinMelanie JeanmichelMarianne ZellerAlain Putot

subject

medicine.medical_specialtymedicine.medical_treatment030204 cardiovascular system & hematologyArticletype 2 myocardial infarctionCoronary artery disease03 medical and health sciences0302 clinical medicineInternal medicinemedicine030212 general & internal medicineMyocardial infarctionhospital mortalitybiologybusiness.industryC-reactive proteinPercutaneous coronary interventionGeneral MedicineOdds ratioEmergency departmentmedicine.diseaseTroponinConfidence intervalmyocardial infarctionCardiologybiology.proteinbusinesscoronary artery disease

description

A type 2 myocardial infarction (T2MI) is the result of an imbalance between oxygen supply and demand, without acute atherothrombosis. T2MI is frequent in emergency departments (ED), but has not been extensively evaluated in patients with previously known coronary artery disease (CAD). Our study assessed the incidence and characteristics of T2MI compared to type 1 (T1MI) in CAD patients admitted to an ED. Among 33,669 consecutive patients admitted to the ED, 2830 patients with T1MI or T2MI were systematically included after prospective adjudication by the attending clinician according to the universal definition. Among them, 619 (22%) patients had a history of CAD. Using multivariable analysis, CAD history was found to be an independent predictive factor of T2MI versus T1MI (odds ratio (95% confidence interval) = 1.38 (1.08&ndash

yearjournalcountryeditionlanguage
2019-12-02Journal of Clinical Medicine
https://doi.org/10.3390/jcm8122100