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RESEARCH PRODUCT

Is there a need to widely prescribe antibiotics in patients hospitalized with COVID-19?

Michel DuongMathieu BlotM. AbdallahouiI. EberlHervé DevilliersS. MahyLionel PirothA. Salmon-rousseauM. BuissonT. SixtPascal ChavanetF. MorettoC. EsteveF. CatherineT. Rogier

subject

Male0301 basic medicineMicrobiology (medical)medicine.medical_specialtymedicine.drug_class030106 microbiologyAntibioticsInfectious and parasitic diseasesRC109-216Articlelaw.inventionHospitals University03 medical and health sciences0302 clinical medicinelawInternal medicinemedicineHumans030212 general & internal medicineMedical prescriptionPropensity ScoreAgedAged 80 and overUnivariate analysisbusiness.industrySARS-CoV-2Hazard ratioCOVID-19General MedicineMiddle AgedAntibiotic therapyPrognosisIntensive care unitConfidence intervalAnti-Bacterial AgentsCOVID-19 Drug TreatmentHospitalizationInfectious DiseasesRadiological weaponSARS-CoV2Propensity score matchingFemaleFrancebusiness

description

Highlights • Antibiotics were a main part of COVID-19 treatments during the first epidemic peak. • Bacterial coinfections seem to be rare, especially if no ICU transfer needed. • We studied the place of antibiotics and the impact on prognosis of patients. • Antibiotics were prescribed if more severe infection and has no impact on prognosis. • We think that antibiotic therapy must be not widely prescribed.

10.1016/j.ijid.2021.01.051http://www.sciencedirect.com/science/article/pii/S120197122100062X