6533b873fe1ef96bd12d56f9

RESEARCH PRODUCT

Jenisseensosides C and D, biologically active acylated triterpene saponins from Silene jenisseensis

Zhen-hua CuiZhen-hua CuiHildebert WagnerBernard HanquetZhi-cen LouZhi-cen LouMarie Aleth Lacaille-dubois

subject

Magnetic Resonance SpectroscopyStereochemistryT-LymphocytesMolecular Sequence DataSaponinPlant ScienceHorticulturePharmacognosyBiologyLymphocyte ActivationBiochemistryHomonuclear moleculePhagocytosisTriterpeneCarbohydrate ConformationHumansMoleculeOleanolic AcidMolecular Biologychemistry.chemical_classificationMolecular StructureBiological activityGeneral MedicineNuclear magnetic resonance spectroscopySaponinsTriterpenesCarbohydrate SequenceHeteronuclear moleculechemistryDrugs Chinese Herbal

description

Abstract We previously reported the isolation and structure elucidation of a new trans - p -methoxycinnamoyl triterpene-saponin along with its cis - p -methoxycinnamoyl isomer as an inseparable mixture from the roots of Silene jenisseensis . In a continuing study on this plant, two additional new acylated triterpene-saponins were obtained as an inseparable mixture. Their structures have been established by chemical means and spectroscopic methods including 1D and 2D homonuclear and heteronuclear correlation NMR spectroscopy as 3- O -[β- d -galactopyranosyl-(1 → 2)-β- d -glucuronopyranosyl]-28- O -[{α- l -rhamnopyranosyl-(1 → 2)}- {4- O - trans - p -methoxycinnamoyl}-β- d -fucopyranosyl] quillaic acid and its cis -isomer, respectively. They showed a significant enhancement of the granulocyte phagocytosis in vitro . © 1997 Elsevier Science Ltd. All rights reserved

yearjournalcountryeditionlanguage
1997-07-01Phytochemistry
https://doi.org/10.1016/s0031-9422(97)00087-3