6533b874fe1ef96bd12d6069

RESEARCH PRODUCT

K Cell Activity of Normal and Chronic Lymphocytic Leukaemia Lymphocytes: Association with Lymphocytes bearing Receptors for Human C3b

U. FinkM. P. DierichH.-d. Flad

subject

Antibody-dependent cell-mediated cytotoxicityeducation.field_of_studyLymphocytic leukaemiaSurface ImmunoglobulinEffectorChemistryLymphocytePopulationchemical and pharmacologic phenomenak-cellMolecular biologymedicine.anatomical_structuremedicineReceptoreducation

description

Surface properties of effector cells in antibody-dependent cell mediated cytotoxicity (ADCC) are at present under intensive investigation. Among these cells a lymphocyte population (K cells) has been described with receptors for the Fc portion of IgG (4), receptors for complement (11) and lacking receptors for sheep red blood cells (SRBC) and surface immunoglobulin (13). The purpose of the present study was to investigate more thoroughly the relationship between K cell activity in ADCC and cells bearing receptors for C3b and C3d.

yearjournalcountryeditionlanguage
1977-01-01
https://doi.org/10.1007/978-3-642-66639-1_23