Struktur-Wirkungs-Beziehungen bei Histaminanaloga, 7. Mitt. Pyridyl- und Piperidyl-histamine

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Struktur-Wirkungs-Beziehungen bei Histaminanaloga, 7. Mitt. Pyridyl- und Piperidyl-histamine

subject

chemistry.chemical_compound Chemistry Drug Discovery Pharmaceutical Science Medicinal chemistry Histamine

description

Es wurden die drei isomeren 2-substituierten Piperidyl-(7) und Pyridyl-histamine (6) aus den entsprechenden 2-substituierten 4-Hydroxymethyl-imidazolen (8) oder 4-(2-Hydroxy-athyl)-imidazolen (3) auf 2 verschiedenen Wegen dargestellt und auf ihre histaminartige Wirksamkeit untersucht. Pyridyl- and Piperidyl-histamines The three 2-substituted histamine isomers of piperidyl-(7) as well as pyridyl-histamines (6) were synthesized from the corresponding 2-substituted 4-hydroxymethyl-imidazoles (8) or 4-(2-hydroxyethyl)-imidazoles (3) by two different ways and tested for their histamine-like activity.

year	journal	country	edition	language
1975-01-01	Archiv der Pharmazie

https://doi.org/10.1002/ardp.19753080604

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