6533b874fe1ef96bd12d63de
RESEARCH PRODUCT
Oxaaza cyclophanes in the recognition of nucleotides. The role of oxygen and electron-rich aromatic rings
Santiago V. LuisD. SroczynskiJuan F. MiravetEnrique García-españaM. I. BurgueteL. López-diagosubject
Models MolecularMagnetic Resonance Spectroscopychemistry.chemical_elementElectronsResorcinolElectronAbiotic ReceptorsHydrocarbons AromaticBiochemistryMedicinal chemistryOxygenchemistry.chemical_compoundCrown EthersOrganic chemistryComputer SimulationNucleotidePhysical and Theoretical Chemistrychemistry.chemical_classificationAqueous solutionNucleotidesChemistryOrganic ChemistryAromaticityOxygenPotentiometryPolyaminedescription
Dioxapolyaza cyclophanes derived from resorcinol and different polyamine chains have been studied in aqueous solution as abiotic receptors for nucleotides. The presence of the additional ethyleneoxy subunits is reflected in a higher basicity and in a significant increase in the log K values for the interaction with nucleotides relative to that of related polyazacyclophanes.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2007-06-07 | Org. Biomol. Chem. |