showing 36 of ~574560 from 574555 documents
Analyse fonctionnelle de mutants affectés dans la biosynthèse de saponines chez le pois
2019
La scelta delle piante destinate al verde ornamentale tra percezioni e cambiamenti: Anthosart green tool, uno strumento per conoscere, selezionare, a…
2019
The presence and importance of plant life on the planet does not seem to reach our sensory perception, therefore activate reactions of interest, and correct ecological behaviour. The increasing number of extinct species witnesses the human oblivion towards ecosystems. The concept of plant blindness describes the phenomenon that produces significant consequences on nature conservation. Urban green infrastructure, part of our daily life, is the right place to re-connect with plant systems. Designing and creating “built green” by means of nature-based solutions and local species pool is the main goal of Anthosart green tool, a free and user-friendly on-line tool, which can be useful for design…
Evaluación de signos tomográficos no exudativos en casos de degeneración macular asociada a la edad de tipo exudativo
2019
Objetivo: analizar la prevalencia de signos tomográficos no exudativos (onion sign, pseudoswelling, tubulación de la retina externa (ORT), pseudoquistes, subretinal clefts y atrofia macular) en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Material y métodos: 174 ojos de pacientes con DMAE neovascular que no habían recibido tratamiento previo fueron incluidos en el estudio. Se valoró la agudeza visual, el espesor central de la retina, la actividad de la neovascularización (NV) y la aparición o no de los distintos signos objeto de estudio en los tiempos 0 (visita inicial), 4 meses, 1 año, año y medio y a los 2 y 3 años de seguimiento. Se evaluaron también: la edad…
Key factors towards a high-quality additive manufacturing process with ABS material
2019
Abstract Additive Manufacturing technologies have gained a lot of popularity during the past years. The current challenge being the transition of this manufacturing technology from prototype oriented towards mass production. In order to achieve this, fabrication times and mechanical parameters must be improved. This paper aims to identify which are the parameters that have the highest influence on parts obtained with fused deposition modeling (FDM) technology from ABS material. In addition, this study identifies which are the most accurate methods to test the mechanical properties of FDM parts while still respecting ASTM standard for testing the tensile properties of plastics. It was found …
A Scheme for Continuous Input to the Tsetlin Machine with Applications to Forecasting Disease Outbreaks
2019
In this paper, we apply a new promising tool for pattern classification, namely, the Tsetlin Machine (TM), to the field of disease forecasting. The TM is interpretable because it is based on manipulating expressions in propositional logic, leveraging a large team of Tsetlin Automata (TA). Apart from being interpretable, this approach is attractive due to its low computational cost and its capacity to handle noise. To attack the problem of forecasting, we introduce a preprocessing method that extends the TM so that it can handle continuous input. Briefly stated, we convert continuous input into a binary representation based on thresholding. The resulting extended TM is evaluated and analyzed…
Additional file 6: of DNA methylation links prenatal smoking exposure to later life health outcomes in offspring
2019
CpG sites and their association with methylation in the ARIES cord blood data. (DOCX 14 kb)
Genetic analysis of populations of brown trout (Salmo truttaL.) from the Romanian Carpathians
2019
The Carpathian Mountains are one of the most complex orogenetic areas of Europe, with unique fauna, including the brown trout (Salmo trutta). In this study we performed population genetic analysis of 12 differentS. truttapopulations using two types of molecular markers: nine microsatellites and mitochondrial D-loop sequences. The following working hypothesis was considered: the Romanian Carpathians and their surrounding lowlands can be key relief units based on which theS. truttagenetic diversity, spread, distribution, connectivity, relative isolation and genetic divergence can be at least partially explained. The phylogenetic analysis revealed that the majority of sequences were grouped in…
Supplementary_material_1 – Supplemental material for Integrating fire-scar, charcoal and fungal spore data to study fire events in the boreal forest …
2019
Supplemental material, Supplementary_material_1 for Integrating fire-scar, charcoal and fungal spore data to study fire events in the boreal forest of northern Europe by Normunds Stivrins, Tuomas Aakala, Liisa Ilvonen, Leena Pasanen, Timo Kuuluvainen, Harri Vasander, Mariusz Gałka, Helena R Disbrey, Janis Liepins, Lasse Holmström and Heikki Seppä in The Holocene
Teaching Green Analytical Chemistry on the Example of Bioindication and Biomonitoring (B & B) Technologies
2019
Teaching of Green Analytical Chemistry (GAC) requires a not inconsiderable willingness on the part of the lecturer to familiarize himself with a relatively new field in analytical chemistry. Although there is much that can be derived from Green and Sustainable Chemistry, the GAC’s forward-looking perspectives in particular are independent approaches that must not be neglected. In the first chapter of this article, approaches are pursued “how (teachers) learn to learn,” ultimately based on a consensus on ethics, which allows dealing with people, society and the environment to become an interdisciplinary unit. The end of all this is a smart method of conflict management which provides solutio…
Intravenous Contrast Agent in Abdominal CT: Is It Really Needed to Identify the Cause of Bowel Obstruction? Proof of Concept
2019
Background. To compare sensitivity of unenhanced computed tomography (CT) and contrast-enhanced CT for the identification of the etiology of bowel obstruction.Materials and Methods. We retrospectively evaluated abdominal CT scans of patients operated for bowel obstruction from March 2013 to October 2017. Two radiologists evaluated CT scans before and after contrast agent in two reading sessions. Then, we calculated sensitivity of CT in the diagnosis of bowel obstruction and determined in which cases the etiology of bowel obstruction was detected on both unenhanced and enhanced CT or on enhanced CT only. The reference standard was defined as the final diagnosis obtained after surgery.Results…
MOESM3 of Leaps and bounds: geographical and ecological distance constrained the colonisation of the Afrotemperate by Erica
2019
Additional file 3. Methods: Biogeographic models; example files for BioGeoBEARS analyses
Additional file 3: of Acting locally - affecting globally: RNA sequencing of gilthead sea bream with a mild Sparicotyle chrysophrii infection reveals…
2019
Pathway classification of DE genes. Bar plots representing the percentage of proteins involved in each broad Reactome pathway. The column labelled Reactome was added as a reference to show the percentage of genes in each category in the database. The other columns represent the percentage of differentially expressed (DE) genes in each category when considering all DE genes in all the tissues of the current experiment (Total) or per tissue, when compared to the control uninfected group. Gill samples are separated in parasitized (P) and non-parasitized (NP) gill sections. (PDF 343 kb)
Multi-class Text Complexity Evaluation via Deep Neural Networks
2019
Automatic Text Complexity Evaluation (ATE) is a natural language processing task which aims to assess texts difficulty taking into account many facets related to complexity. A large number of papers tackle the problem of ATE by means of machine learning algorithms in order to classify texts into complex or simple classes. In this paper, we try to go beyond the methodologies presented so far by introducing a preliminary system based on a deep neural network model whose objective is to classify sentences into more of two classes. Experiments have been carried out on a manually annotated corpus which has been preprocessed in order to make it suitable for the scope of the paper. The results sho…
The pediatric endoscopy practice in Italy: A nationwide survey on behalf of the Italian society of pediatric gastroenterology, hepatology and nutriti…
2019
AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine.
2019
International audience; AGuIX® are sub-5 nm nanoparticles made of a polysiloxane matrix and gadolinium chelates. This nanoparticle has been recently accepted in clinical trials in association with radiotherapy. This review will summarize the principal preclinical results that have led to first in man administration. No evidence of toxicity has been observed during regulatory toxicity tests on two animal species (rodents and monkeys). Biodistributions on different animal models have shown passive uptake in tumours due to enhanced permeability and retention effect combined with renal elimination of the nanoparticles after intravenous administration. High radiosensitizing effect has been obser…
Tunable Optical Antennas Using Vanadium Dioxide Metal-Insulator Phase Transitions
2019
Here, we investigate the possibility of exploiting the insulator-to-metal transition in vanadium dioxide (VO2) to tune and optically control the resonances of dipole nanoantennas in the visible near-infrared region. We compare the results obtained in the case of antennas completely made by VO2 with those of previous works and highlight the key role of the substrate to perform dynamical tuning. We also present a highly efficient configuration composed of dipole gold antenna loaded with VO2 and give some general guidelines to optimally exploit phase transitions to tune nanodevices.
Reconfigurable DNA Origami Nanocapsule for pH-Controlled Encapsulation and Display of Cargo
2019
DNA nanotechnology provides a toolbox for creating custom and precise nanostructures with nanometer-level accuracy. These nano-objects are often static by nature and serve as versatile templates for assembling various molecular components in a user-defined way. In addition to the static structures, the intrinsic programmability of DNA nanostructures allows the design of dynamic devices that can perform predefined tasks when triggered with external stimuli, such as drug delivery vehicles whose cargo display or release can be triggered with a specified physical or chemical cue in the biological environment. Here, we present a DNA origami nanocapsule that can be loaded with cargo and reversibl…
Anti-inflammatory and antioxidant effects of muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampus
2019
AbstractRecently we found that acute treatment with Oxotremorine (Oxo), a non-selective mAChRs agonist, up-regulates heat shock proteins and activates their transcription factor heat shock factor 1 in the rat hippocampus. Here we aimed to investigate: a) if acute treatment with Oxo may regulate pro-inflammatory or anti-inflammatory cytokines and oxidative stress in the rat hippocampus; b) if chronic restraint stress (CRS) induces inflammatory or oxidative alterations in the hippocampus and whether such alterations may be affected by chronic treatment with Oxo. In the acute experiment, rats were injected with single dose of Oxo (0.4 mg/kg) and sacrificed at 24 h, 48 h and 72 h. In the CRS ex…
Material flows, efficiency and decoupling: Latvia's case study
2019
Latvia with its growing economy and intensive use of biomass is one of the biggest per capita natural resource consumers in Europe. If current patterns of resource use are maintained, environmental degradation and depletion of natural resources will continue. This paper looks at the resource flows in Latvia (1995 to 2016) - the country that does not have fossil energy resource deposits and timber industry is an important economic sector contributing most to the direct material input. It analyses the main resource flows, its intensities and looks at the main drivers behind these changes. Results demonstrate that resource extraction and consumption is steadily increasing and are not decoupled…
Understanding the dynamics of field theories far from equilibrium
2019
In recent years, there have been important advances in understanding the far-from-equilibrium dynamics in different physical systems. In ultra-relativistic heavy-ion collisions, the combination of different methods led to the development of a weak-coupling description of the early-time dynamics. The numerical observation of a classical universal attractor played a crucial role for this. Such attractors, also known as non-thermal fixed points (NTFPs), have been now predicted for different scalar and gauge theories. An important universal NTFP emerges in scalar theories modeling ultra-cold atoms, inflation or dark matter, and its scaling properties have been recently observed in an ultra-cold…
Claims secured by a registered pledge in sanation proceedings
2019
This study concerns the legal situation of a receivable secured by a registered pledge in a debtor’s sanation (restructuring) proceedings. The registered pledgee has a special position in the course of such proceedings. The study discusses the rules of subjecting the receivable secured by the arrangement, the rules of preparing and contesting the list of receivables, and finally the rules of satisfying the pledgee.
Studia Organologica, tom VI
2019
Ograniczenie władzy rodzicielskiej jako forma jej wsparcia - rola współpracy sądu opiekuńczego i jednostki wsparcia rodziny
2019
Wielowymiarowość zdrowia
2019
The Quality of Local Self-Governance and the Political Participation of Non-governmental Organizations - Evidence from Silesia
2019
The quality of local authorities performance is determined, among others, by the involvement of social actors in the policy-making process. Among them, it is the non-governmental organisations (NGOs) that play a significant role in local polities, politics and policies. This paper tests if and how the participation of NGOs makes a difference in the quality of local self-governance, based on the evidence from Silesia (2010–2014)—the most densely populated region in Poland. The results show that the NGOs’ involvement diversifies the outcomes in the quality of governance only in a modest way and extend. Consequently, the authors conclude that the politically engaged NGOs do not qualitatively b…
Valistusta ja vuorovaikutusta : turvapaikanhakijoiden laillisuuskasvatus poliisin työssä
2019
Tanssi liikuttaa : toimenpidesuositus Opetushallitukselle, opettajille, opettajankouluttajille, rehtoreille, kunnille ja poliittisille päättäjille
2019
Tanssi on kulttuuria ja taidetta. Samalla se on kokonaisvaltaista, fyysistä toimintaa. Tanssi voi tukea jokaisen peruskoulun oppilaan oppimista, fyysistä aktiivisuutta, kulttuurista osallisuutta ja valmiutta ilmaista itseään monipuolisesti. nonPeerReviewed
Study of J/ψ azimuthal anisotropy at forward rapidity in Pb-Pb collisions at √sNN = 5.02 TeV
2019
The second (v2) and third (v3) flow harmonic coefficients of J/ψ mesons are measured at forward rapidity (2.5 < y < 4.0) in Pb-Pb collisions at sNN−−−√=5.02 TeV with the ALICE detector at the LHC. Results are obtained with the scalar product method and reported as a function of transverse momentum, pT, for various collision centralities. A positive value of J/ψ v3 is observed with 3.7σ significance. The measurements, compared to those of prompt D0 mesons and charged particles at mid-rapidity, indicate an ordering with vn(J/ψ) < vn(D0) < vn(h±) (n = 2, 3) at low and intermediate pT up to 6 GeV/c and a convergence with v2(J/ψ) ≈ v2(D0) ≈ v2(h±) at high pT above 6–8 GeV/c. In semi-central coll…
Teknologia, (mieli)kuvat, historia : Imperialistinen menneisyys ja nykyisyys elokuvissa ja valokuvataiteessa
2019
Ytimessä : kirja kaiken oppimisen keskiöön
2019
”Ytimessä – Kirja kaiken oppimisen keskiöön” on teos, jonka kirjoittamiseen on osallistunut useita pitkään opetusalalla toimineita opettajia, kasvatusalan tutkijoita, koulukirjastonhoitajia ja muita lasten lukemisesta kiinnostuneita toimijoita. Teoksen materiaali on syntynyt 2018 – 2019 Opetushallituksen rahoituksen mahdollistamana. Kirjassa esitellään sekä erilaisia lukemisen projekteja että yksittäisiä työtapoja lukemiseen innostamiseen. Kirjoittajat ovat kokeilleet käytännössä erilaisia lukemisen menetelmiä, erilaisia lukuympäristöjä ja lukemisen yhdistämistä ja integroimista muihin oppiaineisiin ja muuhun opetukseen. Tuloksena on kokonaisvaltaista oppimista ja kokemusta, jossa tiedot, t…
Izglītības iestādes organizācijas kultūras ietekme uz skolēnu mācību sasniegumiem
2019
Bakalaura darba “Izglītības iestādes organizācijas kultūras ietekme uz skolēnu mācību sasniegumiem” mērķis ir pētīt organizācijas kultūras būtību, tās ietekmi uz izglītības iestādi kopumā un kā kultūra ietekmē skolēnu mācību sasniegumus. Mērķa sasniegšanai veikta teorētiskās literatūras analīze par organizācijas kultūras būtību un ietekmi uz izglītības iestādes darbību. Mērķa sasniegšanai tika veikta praktisks pētījums Dobeles 1.vidusskolā. Darbs ir strukturēts četrās nodaļās. Pirmajā nodaļā – organizācijas kultūras veidošanās, kur tiek aplūkots organizācijas kultūras jēdziens, veidošanas faktorus un, kas ietekmē organizācijas kultūru. Otrajā nodaļā - izglītības iestādes kultūra, tās elemen…
Agrīnā pirmsskolas vecuma bērnu kustību koordinācijas attīstība Marijas Montessori praktiskās dzīves vingrinājumos
2019
Pētījuma autors: Ilze Dūze Darba nosaukums: Agrīnā pirmsskolas vecuma bērnu kustību koordinācijas attīstība Marijas Montessori praktiskās dzīves vingrinājumos. Pētījuma priekšmets. Agrīnās pirmsskolas vecuma bērnu kustību koordinācijas attīstība. Pētījuma mērķis: Pētīt agrīnā pirmsskolas vecuma bērnu kustību koordinācijas attīstību M.Montessori vingrinājumos. Pētījuma jautājums: Kā izmantot M.Montessori praktiskās dzīves vingrinājumus, lai tiktu sekmēta bērna kustību koordinācijas attīstība? Materiāli un metodes: 1.Teorētiskās - literatūras analīze. 2.Empīriskās – vingrinājuma demonstrācija, novērošana, bērnu darbības analīze. 3.Matemātiskās - datu apstrāde. Latvijā pētījumi par bērnu kustī…
Co-living jeb kopā dzīvošanas koncepts
2019
Diplomdarba tēma – co-living jeb kopdzīvošanas koncepts kā 21.gadsimta mājokļa alternatīva. Diplomdarba mērķis ir co-living jeb kopā dzīvošanas interjera izveide, integrējot to kādā no pilsētas centra dzīvokļu namiem Darbs sastāv no trīs daļām - teorētiskās, empīriskās un radošās daļas. Teorētiskajā daļā tiks veikts pētījums par mājokļa jēdzienu, komūnu dzīvošanu un to vēsturi, co-housing un co-living jēdzienu un to vēsturi un attīstību mūsdienu kontekstā. Empīriskajā daļā tika izpētīti interjeri, kuros tiek pielietoti co-living principi pasaulē Diplomdarbs sastāv no 4 nodaļām, 13 apakšnodaļām un 3 pielikumiem. Tā apjoms ir 101 lappuse. Darbā izmantoti 51 literatūras avoti. Radošajā daļā ti…
Aktīvās atpūtas tūrisma biznesa modelis
2019
Šajā pētījumā tiek aplūkoti jēdziena "biznesa modelis" konceptuālie aspekti. Tiek aplūkota sociālo mediju ietekme uz piedzīvojumu tūrismu biznesa modeļu inovāciju un klientu vadību. Darba mērķis ir raksturot piedzīvojuma tūrisma biznesa modeli, tā attīstības iespējas apakšnozares ietvaros, un pamatot sociālo mēdiju izmantošanu uzņēmuma komunikācijā. Darba ietvaros tiek veikts neatkarīgs pētījums, kas vērsts uz piedzīvojuma tūrisma pakalpojuma izmantošanu un patērētāju sociālo mēdiju uzvedības novērtējumu. Aktīvās atpūtas biznesa modelis darbā tiek raksturots kā B2C biznesa modelis, kura ietvaros piedāvājums klientam tiek komunicēts digitālajā vidē, bet pakalpojums tiek sniegts dabā, piepras…
Krāsu kategorizācijas un emociju ietekme saskarņu uztverē
2019
Maģistra darba izstrādes laikā autors veica datorzinātņu jomu izpēti, kas ir saistītas ar datora saskarnēm, piemēram, galvenie pētniecības virzieni, to kādi ir noteicošie faktori, lai tās būtu ērti un produktīvi lietojamas un to kā uzlabot lietotāju pieredzi darbā ar saskarnēm. Tika pētīi arī krāsu izmantošanas aspekti saskarnēs, to saistība ar cilvēka emocijās un to kā krāsas var ietekmēt saskarņu uztveri. Ņemot vērā gūtās zināšanas par nozares aktualitāti, nozīmīgākajiem pētniecības virzieniem un galvenajiem elementiem, tika izveidota lietotāju aptauja, kurā tika noskaidrots kādām krāsām cilvēki dot priekšroku, ar kādām emocijām tās saista un kāda veida saskarnēs viņi labprāt redzētu katr…
Pirmsskolas izglītības iestādes sadarbība ar pašvaldību, atbalsta sistēmas veidošanai pedagogiem.
2019
Maģistra darba tēma ir “Pirmsskolas izglītības iestādes sadarbība ar pašvaldību, atbalsta sistēmas veidošanai pedagogiem” un tā mērķis ir pētīt pirmsskolas izglītības iestādes un pašvaldības sadarbību, atbalsta sistēmas veidošanai pirmsskolā. Darba pirmajā nodaļā tiek apskatīta pedagoģiskās un psiholoģiskās atziņas par atbalsta sistēmas jēdzienu un būtību. Tiek noskaidroti dažādi atbalsta sistēmas komponenti, to nozīmīgums pirmsskolas izglītības iestādē. Tiek vērsta uzmanība uz atbalsta sistēmas nozīmīgumu pedagoga darba kvalitātes uzlabošanā. Darba otrajā nodaļā tiek apskatīta pirmsskolas izglītības iestādes un pašvaldības loma atbalsta sistēmas veidošanā. Autore lielu uzmanību vērš uz pir…