Search results for " ADR."

showing 10 items of 284 documents

A survey on features of allergic rhinitis in children

2013

Objective: A number of epidemiologic studies evaluated the prevalence of allergic rhinitis (AR), but few data are available on its different clinical presentations. We addressed this survey to assess the features of AR in children and adolescents. Methods: Thirty-five centers in Italy included 2623 pediatric patients with rhinitis, of whom 2319 suffered from AR, while 304 had other kinds of rhinitis. For each patient a standardized questionnaire was filled in, including ARIA classification, the duration of symptoms, the allergen identified as clinically relevant, the co-morbidities, the kind of treatment, the response to treatment, the satisfaction with the treatment, and the feasibility of…

QuestionnairesMalePediatricsmedicine.disease_causeAdrenal Cortex HormoneAllergic rhinitisDrug treatmentAllergenAdrenal Cortex HormonesGrass pollenSurveys and QuestionnairesChildRhinitisAllergen immunotherapybiologyMedicine (all)PyroglyphidaeGeneral MedicineDust mitesResponse to treatmentPhenotypesPhenotypeItalyChild PreschoolFemaleAdolescent; Adrenal Cortex Hormones; Animals; Child; Child Preschool; Female; Histamine Antagonists; Humans; Italy; Male; Rhinitis Allergic Seasonal; Pyroglyphidae; QuestionnairesHistamine AntagonistHumanallergen immunotherapy; phenotypes; aria classification; allergic rhinitis; drug treatmentmedicine.medical_specialtyAllergen immunotherapyAdolescentHistamine AntagonistsAnimals; Questionnaires; Humans; Pyroglyphidae; Child; Italy; Adrenal Cortex Hormones; Child Preschool; Histamine Antagonists; Rhinitis Allergic Seasonal; Adolescent; Female; MaleAllergen immunotherapy; Allergic rhinitis; ARIA classification; Drug treatment; PhenotypesAllergicmedicineAllergic rhinitiAnimalsHumansPreschoolSettore MED/38 - Pediatria Generale e SpecialisticaSeasonalbusiness.industryAnimalQuestionnairePyroglyphidaeRhinitis Allergic Seasonalbiology.organism_classificationDermatologyClinical trialMulticenter studyARIA classificationbusiness
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α1-Adrenoceptors in the rat cerebral cortex: New insights into the characterization of α1L- and α1D-adrenoceptors

2010

36 p., figuras y tablas, bibliografía

Rat cerebral cortexAdrenergic receptorG proteinInositol PhosphatesBiologyAlpha1-adrenoceptor subtypesBinding CompetitiveCytosolReceptors Adrenergic alpha-1medicineAnimalsRNA MessengerRats WistarBinding siteInositol phosphate[3H]prazosin binding studiesCellular localizationCerebral CortexPharmacologychemistry.chemical_classificationReverse Transcriptase Polymerase Chain ReactionCell MembraneRatsCell biologyCytosolmedicine.anatomical_structureGene Expression RegulationBiochemistrychemistryAlpha1L-adrenoceptorsCerebral cortexG-proteinsFemaleGuanosine TriphosphateIntracellularAlpha1D-intracellular localizationEuropean Journal of Pharmacology
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Probing human beta1- and beta2 -adrenoceptors with domain-specific fusion protein antibodies.

1997

In order to generate antibodies suitable for immunological studies on beta-adrenoceptors constitutively expressed at low levels in cells or tissues we have produced fusion proteins of the amino- and carboxy-terminus, and the second extracellular loop of the human beta 1- or beta 2-adrenoceptors with bacterial glutathione-S-transferase in E. coli. Rabbit antibodies raised against these fusion proteins strongly reacted with intact human beta 1- or beta 2-adrenoceptors in a subtype- and domain-specific manner. Antibodies directed against the second extracellular loop of the beta 1-adrenoceptor reacted stronger with non-denatured receptors and decreased the affinity of the 3H-labelled antagonis…

Recombinant Fusion ProteinsBlotting WesternEnzyme-Linked Immunosorbent AssayBiologyImmunofluorescenceProtein Structure SecondaryAntibodiesRadioligand AssayAntibody SpecificitymedicineExtracellularAnimalsHumansAvidityReceptorFluorescent Antibody Technique IndirectPharmacologymedicine.diagnostic_testMolecular biologyFusion proteinPrimary and secondary antibodiesPrecipitin TestsBlotMicroscopy FluorescenceBiochemistrybiology.proteinRabbitsReceptors Adrenergic beta-2AntibodyReceptors Adrenergic beta-1European journal of pharmacology
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Sant'Antonio Abate

2010

Sant'Antonio Abate GiulianaSant'Antonio Abate Palazzo Adriano
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Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.

1999

The distribution of tricyclic antidepressants from plasma to brain, where these drugs exert their main clinical action, and other organs is related to transport events across the cell membranes of the different tissues. It could be expected that all the molecular features that condition the transport processes (mainly hydrophobicity and molar total charge) also control the pharmacokinetic and biochemical behavior. Micellar liquid chromatography (MLC) has been proposed to emulate in vitro the partitioning process in the biomembranes. The use of micellar solutions of Brij35 as mobile phases in reversed-phase liquid chromatography has proven to be valid to predict the biological activities of …

SerotoninAntidepressive Agents TricyclicModels BiologicalMicellar electrokinetic chromatographyNorepinephrineStructure-Activity RelationshipPharmacokineticsReceptors Adrenergic alpha-1Drug DiscoveryDistribution (pharmacology)AnimalsEnzyme InhibitorsAdrenergic alpha-AntagonistsMicelleschemistry.chemical_classificationChromatographyChemistryCapacity factorRatsMembraneMicellar liquid chromatographyMicellar solutionsAdenylyl Cyclase InhibitorsHistamine H1 AntagonistsMolecular MedicineSelective Serotonin Reuptake InhibitorsTricyclicChromatography LiquidJournal of medicinal chemistry
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L’acarofauna utile (Parasitiformes, Phytoseiidae) associata alle specie forestali del sito Natura 2000 “Bosco di S. Adriano”

2008

Within the acarofauna present in ecosystems, the Phytoseiidae family has a relevant role as it includes species considered as the most important biocontrol agents of phytophagous mites. Their specific composition in various habitats is influenced by numerous factors both biotics and abiotics, while the number of species increases if the complexity of the ecosystem increases. In order to know the specific composition of phytoseiid mites in two natural habitats and to check possible changes in a near future, a survey of phytoseiid mites was carried out in a Natura 2000 location S. Adriano woods (Sicily). This research was done within the project ManagMED “Integrated development and management…

Settore AGR/11 - Entomologia Generale E ApplicataPhytoseiid mites Bosco S. Adriano
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Feeding the brain: the importance of nutrients for brain functions and health

2017

‘We are what we eat’, said the philosopher Feuerbach. In fact, the quality of the food we eat affects our mind as well: the brain, which represents 2% of our body weight, consumes about 20% of the calories we eat each day. Follow a few rules could therefore help to feed properly our brain, so it works to the best of its ability. It is important to know properties of foods especially regarding their aminoacidic composition because aminoacids are components of neurotransmitters, molecules needed for brain transmission and function. It is also possible to choose specific food to prevent or support different diseases that affects nervous system.

Settore BIO/13 - Biologia ApplicataAcetylcholine Adrenaline Brain nutrition Endorphins Neurotransmitters SerotoninSettore MED/26 - Neurologia
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Locus ovatus in formam amphitheatri constructus. Dal Teatro Greco di Villa Adriana al Teatro Olimpico di Palladio

2018

In 1579, at the end of a career studded with prestigious assignments, Andrea Palladio designed for the Olympic Academy a “theater on an ancient model but small and unspeakably beautiful”, as Goethe wrote in his Journey to Italy. A planimetric form, a social function and architectural details, however, severely shows it off from the Vitruvian body of rules of classical theater, enhancing its originality and making it an invention rooted in late-Alexandrian architectures visited and surveyed by Palladio at the Hadrian's Villa in Tivoli.

Settore ICAR/16 - Architettura Degli Interni E AllestimentoTeatro Palladio Villa Adriana classico
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I sistemi di giustizia interna delle Organizzazioni Internazionali: profili amministrativi.

2022

Gli ordinamenti interni delle Organizzazioni Internazionali, che ne regolano la struttura ed il funzionamento in modo autonomo ed indipendente, sono certamente meno completi rispetto agli ordinamenti interni nazionali, ma sono caratterizzati anch’essi da istituzioni ed apparati burocratici complessi votati al perseguimento dei fini pubblici individuati dal trattato costitutivo. Gli ordinamenti delle Organizzazioni Internazionali hanno caratteristiche particolari che, per essere interpretate, richiedono metodologie e strumenti di analisi specifici, nonché categorie giuridiche nuove (o reinterpretate alla luce delle peculiarità del contesto internazionale), e ciò indubbiamente rende difficile…

Settore IUS/10 - Diritto AmministrativoSistemi di giustizia interna ONU WBG ILO funzionari internazionali pubblica amministrazione principi generali codici di condotta sanzioni disciplinari rimedi stragiudiziali rimedi giurisdizionali organi giurisdizionali ADR.
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Adrano, Efesto e i Palici. Culti, interazioni etniche e middle ground nella Sicilia antica

2015

Stranieri o nativi che fossero (εἴτε εἶεν ξένοι εἴτε ἐπιχώριοι), coloro che si accostavano ai santuari dei Palici, di Adrano e di Efesto assumevano un atteggiamento ricettivo e fiducioso, effetto di una strategia “macroretorica” che offriva forme di transazione e di mediazione in un quadro diffuso di conflittualità tra individui e tra gruppi. In questo volume, il ricorso al modello interpretativo del middle ground e al concetto di “porosità” culturale mostra che sia le comunità indigene sia quelle greche si ridefinivano in modi differenti nei diversi contesti spazio-temporali e adattavano la propria struttura identitaria alle più svariate circostanze: dal punto di vista di una “ecologia cul…

Settore L-ANT/02 - Storia GrecaSiculi middle ground interazioni etnicità culti Adrano Efesto PaliciSikels middle ground interactions ethnicity cults Hadranus Hephaistos Palikoi
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