Search results for " Addiction"

Methods for Evaluating the Interaction Between Social Stress and Environmental Enrichment in Animal Models of Nicotine Addiction

2019

The environmental enrichment (EE) paradigm has been evaluated as a means of counteracting some of the consequences of chronic stress in rodents as well as a model of protective environment against drug abuse development. In the present chapter, our main aim is to describe the models of EE and chronic social stress and how they can be applied jointly in order to evaluate the effects of early psychosocial stress in animals exposed of different environments (enriched environment or standard environment). Furthermore, both paradigms could be applied in animal models of nicotine addiction, so the guidelines for the application of a chronic oral nicotine treatment in mice will be described. The h…

D-TMS IN COCAINE ADDICTION: PRELIMINARY FINDINGS

2013

Drug addiction is a brain disease which leads to profound disturbances in an individual’s behaviour. In spite of the progress made in the understanding of the neurobiological mechanisms underlying addiction, expectations from a therapeutic point of view have not been satisfying. Given the modest efficacy of therapeutic tools available, Transcranial Magnetic Stimulation (TMS) seems to be a promising “non-pharmacologic” aid in various neuropathologies(1) including addiction(2) which is characterized by a decrease of dopaminergic activity (DA)(3-4). Thus, ‘restoring’ pre-pathology DA activity may yield clinical benefits in addicts(5). In particular, it has been reported(6) that TMS reduces the…

D-TMS IN COCAINE ADDICTION: preliminary findings

2015

Cocaine-related disorders are currently among the most devastating mental disease as they leads to profound disturbances in an individual’s behaviour resulting in tremendous economic, social, and moral costs. Imaging studies in human have shown a reduction of dopamine (DA) receptors accompanied by a lesser release of endogenous DA in the ventral striatum (AVT) of cocaine subjects thereby resulting in a ‘dopamine-impoverished’ brain[1-2]. This perturbations lead to neuroadpatations in several other circuits which are related to motivation, inhibitory control, and memory which finally determ compulsive-impulsive self drug administration[3]. The lasting reduction in physiological activity of t…

D2R striatopallidal neurons inhibit both locomotor and drug reward processes.

2009

The specific functions of dopamine D(2) receptor-positive (D(2)R) striatopallidal neurons remain poorly understood. Using a genetic mouse model, we found that ablation of D(2)R neurons in the entire striatum induced hyperlocomotion, whereas ablation in the ventral striatum increased amphetamine conditioned place preference. Thus D(2)R striatopallidal neurons limit both locomotion and, unexpectedly, drug reinforcement.

Time perspective and Facebook addiction: The moderating role of neuroticism

2021

The present paper verified the hypothesis that neuroticism moderates the relationship between past-negative or present-fatalistic time perspectives and Facebook addiction. A sample of 248 Facebook users (Female: 66%, mean age: 21.5 years) filled the Zimbardo Time Perspective Inventor and the Facebook Addiction Italian Questionnaire. Two hierarchical regression analyses tested a moderator model in which time perspectives have been defined as independent variables, Facebook addiction as dependent variables, and neuroticism as moderator. Gender and age were introduced in the model as covariates. Results show that past-negative significantly predicts Facebook addiction through the moderation ef…

Hippocampal and Amygdalar Volumes Changes in Drug Addicts: A Preliminary Study

2007

Oral comunication for American Society of Neuroradiology 45th Annual Meeting. Chicago, June 9-14 2007

Er supermosjonisme sunt? : kartlegging av helsevariabler blant mannlige langdistanseløpere og syklister.

2016

Masteroppgave folkehelsevitenskap - Universitetet i Agder 2016 Introduction: Physical activity is well documented as an important factor for good health. There are however some people who train far beyond the national recommendations for 6 physical activity combined with work and family life. The research done on «high volume exercisers» is limited, specially the health variables. Objective: The purpose with this master paper is to investigate if high volume exercise is healthy. By identifying different health variable it may point to how the body responds to high training volume. Method: 41 male high volume exercises (18 to 50 years) were included in this cross-sectional study. The compila…

Diagnostic therapeutic flow-charts for low-back pain patient : the Italian clinical guidelines

2006

A cross-sectional study on smartphone uses among pregnant women attending childbirth classes in the Metropolitan Area of Palermo, Italy: The Stop-Pho…

2022

Background: Prevalence of mobile device addiction has increased over the years; both women and men have assimilated the mobile phone as a central component of their personal existence: integrating it into their lifestyle or becoming so dependent on it that life without it has become unimaginable. Smartphones generate radio-frequency electromagnetic fields. While short-term exposure in adults was considered quite safe, effects of long-term exposure or exposure during pregnancy on fetuses or during breastfeeding on newborns are not well studied yet. The objective of the present study was to investigate the prevalence and usage characteristics of smartphones among a sample of pregnant women, a…

The Binge Eating Scale: Structural Equation Competitive Models, Invariance Measurement Between Sexes, and Relationships With Food Addiction, Impulsiv…

2019

Introduction: The Binge Eating Scale (BES) is a widely used self-report questionnaire to identify compulsive eaters. However, research on the dimensions and psychometric properties of the BES is limited. Objective: The aim of this study was to examine the properties of the Spanish version of the BES. Methods: Confirmatory Factor Analyses (CFAs) were carried out to verify the BES factor structure in a sample of Spanish college students (N = 428, 75.7% women; age range = 18–30). An invariance measurement routine was carried out across sexes, the latent means were compared, and estimates of reliability and convergent and discriminant validity were presented. Results: A one-factor model fit the…