Search results for " Analytical"

showing 10 items of 1453 documents

Evaluation of Flavonoid Derivative and Doxorubicin Effects in Lung Cancer Cells (A549) Using Differential Pulse Voltammetry Method.

2018

Purpose: Electrochemical measurements have prompted the progress as a consequence of their affectability, cost-affectivity and comparatively short examination time. The aim of this study was the fast evaluation of the effect of chemotherapy compounds on the viability of lung cancer cells (A549) via electrochemical methods. Methods: Cyclic voltammetry (CV) was used as a primary method to distinguish between electrochemical behavior of normal and lung cancer cells. Differential pulse voltammetry (DPV) was employed as a complementary analyses method for the impact of doxorubicin (DOX) and Flavonoid modified drug (FMD) (US patent Application number: 62548886) on Lung cancer cells. Results: Only…

medicine.medical_treatmentFlavonoidPharmaceutical SciencePharmacology01 natural sciences0404 agricultural biotechnologyLung neoplasmsElectrochemistrymedicineDoxorubicinGeneral Pharmacology Toxicology and PharmaceuticsLung cancerVoltammetrychemistry.chemical_classificationChemotherapylcsh:RM1-950010401 analytical chemistry04 agricultural and veterinary sciencesmedicine.disease040401 food science0104 chemical scienceslcsh:Therapeutics. PharmacologychemistryDoxorubicinCancer cellVoltammetryDifferential pulse voltammetryCyclic voltammetryResearch Articlemedicine.drugAdvanced pharmaceutical bulletin
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Characterization of the synthetic cannabinoid MDMB-CHMCZCA

2016

The synthetic cannabinoid MDMB-CHMCZCA was characterized by various spectroscopic techniques including NMR spectroscopy and tandem mass spectrometry. The synthetic sample was found to be of S-configuration by VCD spectroscopy and comparison of the data with DFT calculations, while ECD spectroscopy was found to be inconclusive in this case. The enantiomeric purity of samples from test purchases and police seizures was assessed by a self-developed chiral HPLC method.

medicine.medical_treatmentNPS010402 general chemistryTandem mass spectrometry01 natural sciencesFull Research Paperlcsh:QD241-441lcsh:Organic chemistrymedicinelcsh:Sciencechiral HPLCSpectroscopyChromatographyChemistry010401 analytical chemistryOrganic ChemistryNuclear magnetic resonance spectroscopy0104 chemical sciencesCharacterization (materials science)Chiral column chromatographyChemistryVCD spectroscopyECD spectroscopylcsh:QCannabinoidEnantiomersynthetic cannabinoidsBeilstein Journal of Organic Chemistry
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Determination of metal concentrations in certified plastic reference materials after small-size autoclave and microwave-assisted digestion followed w…

2017

Abstract The digestion methods for the determination of As, Cd, Cr, Pb, Sb, Sn and Zn concentrations in plastic samples using microwave-assisted digestion (MW-AD) and small-size autoclave digestion was developed. The certified polyethylene, polypropylene, polyvinyl chloride and acrylonitrile butadiene styrene certified reference materials were used in order to find digestion method working properly for several sample matrices. Efficiency of the digestion methods was evaluated by analyzing the residual carbon in digests by TOC analyzer. MW-AD using a mixture of 7 mL of HNO 3 and 3 mL of H 2 O 2 as a digestion solution resulted in excellent recoveries for As, Cd, Pb, Sb and Zn, and were in th…

microwavedigestion010402 general chemistry01 natural sciencesAnalytical ChemistryAutoclavechemistry.chemical_compounddeterminationDigestion (alchemy)plasticta116InstrumentationSpectroscopyPolypropyleneautoclaveChromatographyAcrylonitrile butadiene styreneruoansulatus010401 analytical chemistryAtomic and Molecular Physics and Optics0104 chemical sciencesPolyvinyl chlorideCertified reference materialschemistrymuoviInductively coupled plasma atomic emission spectroscopyICP-OESInductively coupled plasmaSpectrochimica Acta Part B: Atomic Spectroscopy
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Discrimination of almonds (Prunus dulcis) geographical origin by minerals and fatty acids profiling

2016

Twenty-one almond samples from three different geographical origins (Sicily, Spain and California) were investigated by determining minerals and fatty acids compositions. Data were used to discriminate by chemometry almond origin by linear discriminant analysis. With respect to previous PCA profiling studies, this work provides a simpler analytical protocol for the identification of almonds geographical origin. Classification by using mineral contents data only was correct in 77% of the samples, while, by using fatty acid profiles, the percentages of samples correctly classified reached 82%. The coupling of mineral contents and fatty acid profiles lead to an increased efficiency of the clas…

mineralPlant ScienceAlmond01 natural sciencesBiochemistryCaliforniaAnalytical ChemistryPlant scienceBotanyFood scienceSicilychemistry.chemical_classificationMineralsgeographical originGeography010405 organic chemistryMedicine (all)010401 analytical chemistryFatty AcidsOrganic Chemistryfood and beveragesFatty acidPrunus dulciPrunus dulcis0104 chemical sciencesPrunus dulcischemistrySpainfatty acid
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Indirect chronology method employing rare earth elements to identify Sagunto Castle mortar construction periods

2017

A novel indirect chronology method has been developed to identify Sagunto Castle construction periods. The method is based on the use of inductively coupled plasma mass spectrometry (ICP-MS) to determine rare earth elements (REE) and other trace elements in mortars. Additionally, a no destructive geochemical analysis based on X-ray fluorescence (XRF) was employed for major elements determination. Collected chemical data were processed through Principal Component Analysis (PCA) to highlight any differences among the mortars belonging to different buildings and construction periods. The results show that PCA analysis permits to discriminate construction periods according to mortar sample REE …

multivariate statistics060102 archaeologyRare Earth Elements (REE)010401 analytical chemistryRare earthChemical dataMineralogyindirect chronology06 humanities and the artsMortar Rare Earth Elements (REE) ICP-MS multivariate statistics indirect chronology Sagunto Castle.01 natural sciencesSagunto Castle0104 chemical sciencesAnalytical ChemistryMortarStratigraphyPrincipal component analysisICP-MS0601 history and archaeologyMortarInductively coupled plasma mass spectrometrySpectroscopyGeologyChronologyMicrochemical Journal
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Amorphous Polyphosphate and Ca‐Carbonate Nanoparticles Improve the Self‐Healing Properties of both Technical and Medical Cements

2020

Cement is used both as a construction material and for medical applications. Previously, it has been shown that the physiological polymer inorganic polyphosphate (polyP) is morphogenetically active in regeneration of skin, bone, and cartilage. The present study investigates the question if this polymer is also a suitable additive to improve the self-healing capacity not only of construction cement but also of inorganic bone void fillers. For the application in the cement, two different polyP-based amorphous nanoparticles (NP) are prepared, amorphous Ca-polyP NP and amorphous Ca-carbonate (ACC) NP. The particles are integrated into poly(methyl methacrylate) in a concentration ratio of 1:10. …

musculoskeletal diseases0106 biological sciencesMaterials sciencePolymersCarbonatesNanoparticle01 natural sciencesApplied Microbiology and BiotechnologyBone and Boneslaw.inventionchemistry.chemical_compoundlawPolyphosphates010608 biotechnologyCementchemistry.chemical_classificationConstruction MaterialsPolyphosphate010401 analytical chemistrytechnology industry and agricultureGeneral MedicinePolymerBone cementAmorphous calcium carbonate0104 chemical sciences3. Good healthAmorphous solidPortland cementsurgical procedures operativechemistryChemical engineeringMolecular MedicineNanoparticlesCalciumBiotechnology Journal
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Ethyl hexanoate transfer in paper and plastic food packaging by sorption and permeation experiments

2008

The barrier properties of one treated paper packaging and one standard plastic film (bi-oriented polypropylene, biOPP) were assessed for ethyl hexanoate. Three methods based either on sorption (gravimetry and micro-atmosphere-derived method) or permeation kinetic determination were used in controlled conditions of aroma vapor concentration (107 Pa), temperature (25 degrees C) and relative humidity (about 0 %). Ethyl hexanoate solubility values were on the same range of magnitude for both packaging films in spite of their different nature and composition. Ethyl hexanoate affinity for both films was well predicted by their respective solubility parameters. Solubility values were different acc…

packagingAnalytical chemistryinteractionThermal diffusivity01 natural sciencesmethodschemistry.chemical_compound0404 agricultural biotechnology[SDV.IDA]Life Sciences [q-bio]/Food engineeringRelative humiditySolubilityPolypropylenearoma compoundChromatographyChemistrysolubility010401 analytical chemistry[ SDV.IDA ] Life Sciences [q-bio]/Food engineeringEthyl hexanoateSorptiondiffusivity04 agricultural and veterinary sciencesPermeation040401 food science0104 chemical sciences[ CHIM.POLY ] Chemical Sciences/PolymersHildebrand solubility parameter[CHIM.POLY]Chemical Sciences/PolymerspermeabilityFood Science
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Production and Characterization of Medium-Sized and Short Antioxidant Peptides from Soy Flour-Simulated Gastrointestinal Hydrolysate.

2021

Soybeans (Glycine max) are an excellent source of dietary proteins and peptides with potential biological activities, such as antihypertensive, anti-cholesterol, and antioxidant activity

peptidomicAntioxidantPhysiologymedicine.medical_treatmentClinical BiochemistryeducationPeptideRM1-950Fractionationantioxidative activity; bioactive peptides; mass spectrometry; peptidomics; soybean01 natural sciencesBiochemistryHydrolysateArticle0404 agricultural biotechnologymedicineDatabase search enginesoybeanMolecular Biologymass spectrometrychemistry.chemical_classification010401 analytical chemistryantioxidative activitypeptidomicsfood and beverages04 agricultural and veterinary sciencesCell Biology040401 food sciencehumanities0104 chemical sciencesAmino acidBiochemistrychemistrybioactive peptideGlycineTherapeutics. Pharmacologybioactive peptidesSoy flourAntioxidants (Basel, Switzerland)
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Non-Occupational Exposure to Pesticides: Experimental Approaches and Analytical Techniques (from 2019)

2021

© 2021 by the authors.

pesticide residuesNon occupationalenvironmental exposurePharmaceutical ScienceOrganic chemistryReview010501 environmental scienceshuman health01 natural sciencesGas Chromatography-Mass SpectrometryMass SpectrometryAnalytical ChemistryGlobal populationHuman healthQD241-441Environmental healthDrug DiscoveryPlaguicidesHealth Status IndicatorsHumansPesticidesPhysical and Theoretical ChemistrySolvent extractionestimated intakesChromatography High Pressure Liquid0105 earth and related environmental sciencesPesticide residueSolid Phase Extraction010401 analytical chemistryindirect estimationdirect estimationEnvironmental exposureQuímicaPesticide0104 chemical scienceswastewater-based epidemiologyChemistry (miscellaneous)Human exposureSolventsMolecular MedicineEnvironmental scienceMolecules
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Improvement of partition coefficients determination of aroma compounds in food matrices by the phase ratio variation method

2011

The Phase Ratio Variation (PRV) method is a very valuable method commonly used for liquid/vapor partition coefficients data acquisition of aroma compounds. Nevertheless, some limits are linked to this method, especially for volatile compounds. A careful examination of the PRV equation leads us to propose the following expression: 1/Cvap-real =(nliq/n0) x 1/Cvap-ideal = (nliq/n0) x (1/KC0 + (1/Co) b), We performed an examination for two cases of K values (K1=0.001 and K2=0.05), putting forward that a carefully choice of b range values is crucial for reliability of the regression calculation 1/A versus b.

phase ratio variation (PRv)[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionAnalytical chemistryIngénierie des alimentspartition coefficient01 natural sciencesaroma retention-release0404 agricultural biotechnology[SDV.IDA]Life Sciences [q-bio]/Food engineeringFood and NutritionFood engineeringAromaComputingMilieux_MISCELLANEOUSbiologyChemistry010401 analytical chemistry[ SDV.IDA ] Life Sciences [q-bio]/Food engineering04 agricultural and veterinary sciencesbiology.organism_classification040401 food science0104 chemical sciencesPartition coefficient[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionphase ratio variation (PRv);partition coefficient;liquid vapor equilibrium;aroma retention-releasePhase ratioAlimentation et Nutritionliquid vapor equilibriumComputingMethodologies_GENERAL[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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