Search results for " Applications"
showing 10 items of 4541 documents
TWO-LANE TRAFFIC WITH PLACES OF OBSTRUCTION TO TRAFFIC
2004
As the Nagel–Schreckenberg model (NaSch model) became known as a realistic approach to describe traffic flow on single-lane streets, this model was extended to two-lane traffic by several groups. On the base of our two-lane model, we will now investigate the impact of a place of obstruction, e.g., because of road works, on partial fractions, densities and mean velocities.
2004
This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises 315 AO molecules including 68 features each, inducing a problem well-suited to SVMs. The task of feature selection is crucial given the presence of noisy or redundant features, and the well-known problem of the curse of dimensionality. We propose a two-stage strategy to develop an optimal model: (1) feature selection using correlation analysis, mutual information, and SVM-based recursive feature elimination (SVM-RFE), and (2) AO prediction using standard and profiled SVM formulations. A profiled SVM gives different weights to …
mTOR Driven Gene Transcription Is Required for Cholesterol Production in Neurons of the Developing Cerebral Cortex
2021
AbstractDysregulated mammalian target of rapamycin (mTOR) activity is associated with various neurodevelopmental disorders ranging from idiopathic autism spectrum disorders to syndromes caused by single gene defects. This suggests that maintaining mTOR activity levels in a physiological range is essential for brain development and functioning. Upon activation, mTOR regulates a variety of cellular processes such as cell growth, autophagy and metabolism. On a molecular level, however, the consequences of mTOR activation in the brain are not well understood.Low levels of cholesterol are associated with a wide variety of neurodevelopmental disorders. We here describe numerous genes of the stero…
A Compact SPICE Model for Organic TFTs and Applications to Logic Circuit Design
2016
This work introduces a compact DC model developed for organic thin film transistors (OTFTs) and its SPICE implementation. The model relies on a modified version of the gradual channel approximation that takes into account the contact effects, occurring at nonohmic metal/organic semiconductor junctions, modeling them as reverse biased Schottky diodes. The model also comprises channel length modulation and scalability of drain current with respect to channel length. To show the suitability of the model, we used it to design an inverter and a ring oscillator circuit. Furthermore, an experimental validation of the OTFTs has been done at the level of the single device as well as with a discrete-…
Improved heuristics for the regenerator location problem
2014
Telecommunication systems use optical signals to transmit information. The strength of a signal in an optical network deteriorates and loses power as it goes farther from the source, mainly due to attenuation. Therefore, to enable the signal to arrive its intended destination with good quality, it is necessary to regenerate the signal periodically using regenerators. These components are relatively expensive and therefore it is desirable to deploy as few of them as possible in the network. In the regenerator location problem (RLP), we are given an undirected graph, positive edge lengths, and a parameter specifying the maximum length that a signal can travel before its quality deteriorates a…
Revisión de la Literatura sobre la Toma de Decisiones Éticas en Organizaciones
2019
espanolEste articulo revisa la literatura sobre el tema de toma de decisiones eticas en organizaciones, para establecer sus niveles de integracion disciplinar, enfoques teoricos y metodos dominantes. Con ese fin, se combino la busqueda sistematica con la narrativa. La sistematica se baso en referencias extraidas de Web of Science (WoS), analizadas mediante la plataforma Tree of Science (ToS) para identificar redes de citacion. La narrativa se apoyo en el analisis de referencias complementarias a traves del programa Gephi. La literatura se clasifico en tres niveles de dialogo disciplinar: 1) Importacion conceptual; 2) Reciprocidad teorica; y 3) Unidad teorica. Se concluye que la escasez de e…
Right-arm rotation distance between binary trees
2003
We consider a transformation on binary trees, named right-arm rotation, which is a special instance of the well-known rotation transformation. Only rotations at nodes of the right arm of the trees are allowed. Using ordinal tools, we give an efficient algorithm for computing the right-arm rotation distance between two binary trees, i.e., the minimum number of rightarm rotations necessary to transform one tree into the other.
THE IMPACT OF ELECTION RESULTS ON THE MEMBER NUMBERS OF THE LARGE PARTIES IN BAVARIA AND GERMANY
2005
In this paper, we investigate the relations between the numbers of members of various parties and their results in the elections in Bavaria and in Germany. Deriving from the finding that there is a strong time-delayed correlation between these data-sets for the two largest parties in Bavaria, we show in a simulation based on the Sznajd model that such a correlation leads to very stable majorities, just as in Bavaria.
Advanced Virgo Status
2015
Abstract The detection of a gravitational wave signal in September 2015 by LIGO interferometers, announced jointly by LIGO collaboration and Virgo collaboration in February 2016, opened a new era in Astrophysics and brought to the whole community a new way to look at - or “listen” to - the Universe. In this regard, the next big step was the joint observation with at least three detectors at the same time. This configuration provides a twofold benefit: it increases the signal-to-noise ratio of the events by means of triple coincidence and allows a narrower pinpointing of GW sources, and, in turn, the search for Electromagnetic counterparts to GW signals. Advanced Virgo (AdV) is the second ge…