Search results for " Axis"
showing 10 items of 188 documents
Host microbiota constantly control maturation and function of microglia in the CNS.
2015
As the tissue macrophages of the CNS, microglia are critically involved in diseases of the CNS. However, it remains unknown what controls their maturation and activation under homeostatic conditions. We observed substantial contributions of the host microbiota to microglia homeostasis, as germ-free (GF) mice displayed global defects in microglia with altered cell proportions and an immature phenotype, leading to impaired innate immune responses. Temporal eradication of host microbiota severely changed microglia properties. Limited microbiota complexity also resulted in defective microglia. In contrast, recolonization with a complex microbiota partially restored microglia features. We determ…
Composition of a Neuromere and Its Segmental Diversification under the Control ofHoxGenes in the Embryonic CNS ofDrosophila
2014
Studies performed at the level of single, identified cells in the fruitfly Drosophila have decisively contributed to our understanding of the mechanisms underlying the development and function of the nervous system. This review highlights some of the work based on single-cell analyses in the embryonic/larval CNS that sheds light on the principles underlying formation and organization of an entire segmental unit and its divergence along the anterior/posterior body axis.
Anisotropy of the refractive index and absorption coefficient in the layer plane of gallium telluride single crystals
1995
Refractive index and absorption coefficient of GaTe for light polarized in the optical axis directions in the layer plane are determined from transmission measurements. The refractive index is determined in the wavelength range from 0.7 to 25 μm and the absorption coefficient in the range of energies from 1.6 to 2 eV at room temperature and at 30 K. The optical constants are found to be anisotropic in the layer plane. The refractive index dispersion is interpreted through a Phillips-Van Vechten model and the Penn gaps for each direction are found to be E pg (⊥b) = 3.37 eV and E pg (∥b) = 3.58 eV. In the long-wavelength region a polar phonon contribution is also taken into account. The absor…
Rotation correlation time as a measure of microviscosity of excited state isomerization reactions of three cyanine dyes in n-alcohol solutions
1994
Abstract Rotation correlation times of three chemically similar cyanine dyes of different sizes in n -alcohol solutions have been recorded at several temperatures by using polarized picosecond spectroscopy. For all three dyes the linear temperature dependencies of τ or on η/ T were observed to be independent of solvent up to viscosities of about 60 cP. The rotational motion of the dyes proceeds at much slower rates than the excited state isomerization in viscous solutions of the same fluidity. Isomerization seems to depend on special solvent-induced changes of the force field of the reactant and clearly proceeds faster, especially for the two larger dyes, than predicted by Kramers' theory a…
Translational and rotational molecular motion in supercooled liquids studied by NMR and forced Rayleigh scattering
1994
It has been shown that translational diffusion coefficients, Dt, in the supercooled van der Waals liquids, orthoterphenyl, phenolphthaleindimethylether, and salol, have a weaker temperature dependence than the shear viscosity, η, at T ≲ 1.2Tg and can be described by Dt ∼ η−χ with χ < 1 whereas Dr ∼ η−1 applies for the mean rotational diffusion coefficients, Dr, down to the glass transition temperature, Tg. This apparent decoupling of translational and rotational motion has been discussed in relation with possible anomalous short time diffusion, spatial heterogeneity, and cooperative molecular motions close to Tg.
Immunological Aspects of Von Hippel-Lindau Disease: A Focus on Neuro-Oncology and Myasthenia Gravis
2022
Von Hippel-Lindau (VHL) disease is an autosomal dominant condition that predisposes affected individuals to a variety of malignant and benign neoplasms. The pathogenetic turning point of this illness is the accumulation of hypoxia-inducible factor (HIF)-1α, a transcription factor of several genes involved in oncogenesis, angiogenesis, tissue regeneration, metabolic regulation, hematopoiesis, and inflammatory responses. From an oncological perspective, increased awareness of the molecular pathways underlying this disease is bringing us closer to the development of specific and targeted therapies. Meanwhile, on the surgical side, improved understanding can help to better identify the patients…
Designing an innovative system for sea wave utilization
2018
For the sea wave energy exploitation, the department of Energy of Palermo University is investigating a new approach based on the mechanical motion conversion from a linear motion into a unidirectional rotary motion. This mechanical output can be used to run alternators, producing electrical power with a very simplified energy conversion chain. First preliminary tests have been realized in laboratory using a small-scale prototype.
An innovative mechanical motion converter for sea wave applications
2018
The paper shows an innovative system designed and developed by University of Palermo. The device is based on a simple mechanical converter able to transform a variable bidirectional linear motion into a unidirectional rotary motion. This technology can be successful used in sea wave applications, producing a mechanical output usable for the electrical energy production.
An Alternative to Medial Axis for the 3D Reconstruction of Unorganized Set of Points Using Implicit Surfaces
2006
Rebuilding three-dimensional objects represented by a set of points is a classical problem in computer graphics. Multiple applications like medical imaging or industrial techniques require finding shape from scattered data. Therefore, the reconstruction of a set of points that represents a shape has been widely studied, depending on data source and reconstruction's objectives. This purpose of this paper is to provide an automatic reconstruction from an unorganized cloud describing an unknown shape in order to provide a solution that will allow to compute the object's volume and to deform it with constant volume. The main idea in this paper consists in filling the object's interior with an e…
Topology guaranteeing manifold reconstruction using distance function to noisy data
2006
Given a smooth compact codimension one submanifold S of Rk and a compact approximation K of S, we prove that it is possible to reconstruct S and to approximate the medial axis of S with topological guarantees using unions of balls centered on K. We consider two notions of noisy-approximation that generalize sampling conditions introduced by Amenta & al. and Dey & al. Our results are based upon critical point theory for distance functions. For the two approximation conditions, we prove that the connected components of the boundary of unions of balls centered on K are isotopic to S. Our results allow to consider balls of different radii. For the first approximation condition, we also prove th…