6533b7dafe1ef96bd126e407

RESEARCH PRODUCT

Composition of a Neuromere and Its Segmental Diversification under the Control ofHoxGenes in the Embryonic CNS ofDrosophila

Oliver BirkholzChristof RickertChristian BergerAna Rogulja-ortmannGerhard M. Technau

subject

Central Nervous SystemNervous systemGeneticsbiologyGenes HomeoboxCell lineagebiology.organism_classificationNeuromereEmbryonic stem cellCellular and Molecular Neurosciencemedicine.anatomical_structureBody axisEvolutionary biologyGeneticsmedicineAnimalsDrosophila ProteinsDrosophilaDrosophila (subgenus)Hox geneFunction (biology)Body Patterning

description

Studies performed at the level of single, identified cells in the fruitfly Drosophila have decisively contributed to our understanding of the mechanisms underlying the development and function of the nervous system. This review highlights some of the work based on single-cell analyses in the embryonic/larval CNS that sheds light on the principles underlying formation and organization of an entire segmental unit and its divergence along the anterior/posterior body axis.

https://doi.org/10.3109/01677063.2013.868459