Search results for " Biochemistry"

showing 10 items of 5648 documents

Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance.

2000

AbstractPosttranscriptional gene silencing (PTGS) in plants results from the degradation of mRNAs and shows phenomenological similarities with quelling in fungi and RNAi in animals. Here, we report the isolation of sgs2 and sgs3 Arabidopsis mutants impaired in PTGS. We establish a mechanistic link between PTGS, quelling, and RNAi since the Arabidopsis SGS2 protein is similar to an RNA-dependent RNA polymerase like N. crassa QDE-1, controlling quelling, and C. elegans EGO-1, controlling RNAi. In contrast, SGS3 shows no significant similarity with any known or putative protein, thus defining a specific step of PTGS in plants. Both sgs2 and sgs3 mutants show enhanced susceptibility to virus, d…

0106 biological sciencesRNA-induced transcriptional silencingDNA PlantRNA-induced silencing complexTrans-acting siRNAMolecular Sequence DataPotyvirusArabidopsisRNA-dependent RNA polymerase[SDV.BC]Life Sciences [q-bio]/Cellular BiologyGenes Plant01 natural sciencesCucumovirusGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesSolanum lycopersicumRNA interferenceArabidopsisGene expressionGene silencingAmino Acid SequenceGene SilencingCloning MolecularRNA Processing Post-Transcriptional[SDV.BC] Life Sciences [q-bio]/Cellular BiologyComputingMilieux_MISCELLANEOUS030304 developmental biologyPlant DiseasesPlant ProteinsGenetics0303 health sciencesbiologyBase SequenceBiochemistry Genetics and Molecular Biology(all)Arabidopsis ProteinsfungiTobamovirusChromosome MappingGENETIQUEbiology.organism_classificationRNA-Dependent RNA PolymeraseMutagenesis010606 plant biology & botanyCell
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Gene flow relates to evolutionary divergence among populations at the range margin

2020

Background Morphological differentiation between populations resulting from local adaptations to environmental conditions is likely to be more pronounced in populations with increasing genetic isolation. In a previous study a positive clinal variation in body size was observed in isolated Roesel’s bush-cricket, Metrioptera roeselii, populations, but were absent from populations within a continuous distribution at the same latitudinal range. This observational study inferred that there was a phenotypic effect of gene flow on climate-induced selection in this species. Methods To disentangle genetic versus environmental drivers of population differences in morphology, we measured the size of …

0106 biological sciencesRange (biology)Climatelcsh:MedicineBody sizeBiology010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyGene flowEvolutionsbiologi03 medical and health sciencesAdaptive divergenceMargin (machine learning)GeneticsGenetikGenetic isolation030304 developmental biologyEvolutionary Biology0303 health sciencesEcologyMorphological differentiationGeneral Neurosciencelcsh:RVDP::Matematikk og Naturvitenskap: 400Body sizeGeneral MedicineEvolutionary StudiesEvolutionary biologyOrthopteraEvolutionary divergenceGeneral Agricultural and Biological SciencesEntomologyZoologyGenetic isolatePeerJ
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Quantifying and addressing the prevalence and bias of study designs in the environmental and social sciences

2020

Building trust in science and evidence-based decision-making depends heavily on the credibility of studies and their findings. Researchers employ many different study designs that vary in their risk of bias to evaluate the true effect of interventions or impacts. Here, we empirically quantify, on a large scale, the prevalence of different study designs and the magnitude of bias in their estimates. Randomised designs and controlled observational designs with pre-intervention sampling were used by just 23% of intervention studies in biodiversity conservation, and 36% of intervention studies in social science. We demonstrate, through pairwise within-study comparisons across 49 environmental da…

0106 biological sciencesResearch designScientific communitySCIENTIFIC COMMUNITYMedio ambiente naturalsosiaalitieteetPsychological interventionGeneral Physics and AstronomySocial SciencesQH7501 natural sciencesEnvironmental impact//purl.org/becyt/ford/1 [https]010104 statistics & probability/706/648CredibilityPrevalenceSocial scienceComputingMilieux_MISCELLANEOUSGEMultidisciplinaryEcologyQarticleSampling (statistics)Biodiversitynäyttöön perustuvat käytännötsatunnaistetut vertailukokeetENVIRONMENTAL IMPACTResearch designResearch DesignScale (social sciences)[SDE]Environmental SciencesH1ScienceEnvironment010603 evolutionary biologyGeneral Biochemistry Genetics and Molecular BiologySocial sciencesBiastutkimusmenetelmätQH541/704/172/4081Humans0101 mathematics//purl.org/becyt/ford/1.6 [https]ympäristötieteetpoliittinen päätöksentekoClinical study designmetodologia/706/689General Chemistry15. Life on landEcologíaLiteraturePairwise comparisonObservational study/631/158luotettavuusBias; Biodiversity; Ecology; Environment; Humans; Literature; Prevalence; Research Design; Social SciencesNature Communications
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Ecological dependencies make remote reef fish communities most vulnerable to coral loss

2021

Ecosystems face both local hazards, such as over-exploitation, and global hazards, such as climate change. Since the impact of local hazards attenuates with distance from humans, local extinction risk should decrease with remoteness, making faraway areas safe havens for biodiversity. However, isolation and reduced anthropogenic disturbance may increase ecological specialization in remote communities, and hence their vulnerability to secondary effects of diversity loss propagating through networks of interacting species. We show this to be true for reef fish communities across the globe. An increase in fish-coral dependency with the distance of coral reefs from human settlements, paired with…

0106 biological sciencesRichnessconservation biologyekologiset verkostotGeneral Physics and Astronomy01 natural sciencesConservation of Natural ResourceAnthropogenic EffectmeriekologiaPatterns0303 health sciencesDiversityMultidisciplinaryConservation biologyCoral ReefsAnthropogenic EffectsQClimate-change ecologyFishesBiodiversityAnthozoaHabitat1181 Ecology evolutionary biologyCoral ReefHumanclimate-change ecologyConservation of Natural Resources[SDE.MCG]Environmental Sciences/Global ChangesScienceClimate ChangeBiotic interactions010603 evolutionary biologyGeneral Biochemistry Genetics and Molecular BiologyArticlekoralliriutat03 medical and health sciencesAnimals; Anthozoa; Anthropogenic Effects; Biodiversity; Climate Change; Conservation of Natural Resources; Coral Bleaching; Fishes; Humans; Spatial Analysis; Coral ReefsFood-webAnimalsHumansecological networks14. Life underwater030304 developmental biologySpatial AnalysisCoral BleachingAnimalkalakannatGeneral ChemistryDisturbanceSpatial Analysiilmastonmuutokset15. Life on landbiodiversiteetti13. Climate actionEcological networks[SDE.BE]Environmental Sciences/Biodiversity and EcologyFisheNature Communications
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Effect of temperature on pollen germination for several Rosaceae species: influence of freezing conservation time on germination patterns

2019

[EN] Between February 2018 and April 2018, flowers were collected from eight Rosaceae species. Flowers were kept in a freezer at -20 degrees C for three freezing times (Treatment 1, two months; Treatment 2, four months; Treatment 3, six months). After extracting pollen, in vitro germination was induced in a culture medium and incubated at six different temperatures for 72 h. The percentage of pollen germination, average pollen tube length and maximum pollen tube length were measured. Pollen germination was maximum for all species between 15 degrees C and 30 degrees C. Cydonia oblonga, Malus sylvestris, Prunus avium, Prunus domestica, Prunus dulcis, Prunus persica and Pyrus communis obtained…

0106 biological sciencesRosaceaePlumBOTANICAlcsh:MedicinePlant ScienceAlmondmedicine.disease_cause010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyPrunus cerasiferaPrunusPollenPollen tube lengthotorhinolaryngologic diseasesmedicineCherryAgricultural SciencebiologyGeneral NeuroscienceQuincelcsh:RApplefood and beveragesGeneral Medicinebiology.organism_classificationPeachPrunus dulcisHorticultureGerminationPollen germinationPearPollen tubeGeneral Agricultural and Biological Sciences010606 plant biology & botanyPyrus communis
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Adaptation in response to environmental unpredictability

2017

Understanding how organisms adaptively respond to environmental fluctuations is a fundamental question in evolutionary biology. The Mediterranean region typically exhibits levels of environmental unpredictability that vary greatly in habitats over small geographical scales. In cyclically parthenogenetic rotifers, clonal proliferation occurs along with occasional bouts of sex. These bouts contribute to the production of diapausing eggs, which allows survival between growing seasons. Here, we studied two diapause-related traits in rotifers using clones from nine Brachionus plicatilis natural populations that vary in the degree of environmental unpredictability. We tested the hypothesis that …

0106 biological sciencesRotiferaZoologyGrowing seasonEnvironmentDiapause010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyLife history theoryGenetic variationAnimalsOvumGeneral Environmental ScienceLocal adaptationEcologyGeneral Immunology and MicrobiologybiologyHatchingReproduction010604 marine biology & hydrobiologyGeneral MedicineBrachionusbiology.organism_classificationBiological EvolutionDiapauseAdaptationGeneral Agricultural and Biological SciencesProceedings of the Royal Society B: Biological Sciences
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Can video playback provide social information for foraging blue tits?

2017

Video playback is becoming a common method for manipulating social stimuli in experiments. Parid tits are one of the most commonly studied groups of wild birds. However, it is not yet clear if tits respond to video playback or how their behavioural responses should be measured. Behaviours may also differ depending on what they observe demonstrators encountering. Here we present blue tits (Cyanistes caeruleus) videos of demonstrators discovering palatable or aversive prey (injected with bittertasting Bitrex) from coloured feeding cups. First we quantify variation in demonstrators’ responses to the prey items: aversive prey provoked high rates of beak wiping and head shaking. We then show tha…

0106 biological sciencesSELECTIONForage (honey bee)Computer scienceForagingsocial information uselcsh:MedicineCommon methodECOLOGY010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyPredationMECHANISMSSYSTEMS0501 psychology and cognitive sciences050102 behavioral science & comparative psychologySocial informationCommunicationblue titsbiologyAnimal Behaviorbusiness.industryGeneral Neuroscience05 social sciencesCyanisteslcsh:RANIMALSGeneral MedicineSocial cuebiology.organism_classificationEvolutionary StudiesGALLUS-GALLUSBeakSTIMULI1181 Ecology evolutionary biologyZEBRA FINCHESMATEta1181General Agricultural and Biological Sciencesbusinessvideo-playbackBEHAVIORPeerJ
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Reducing the effect of beauvericin on neuroblastoma SH-SY5Y cell line by natural products

2020

Abstract In the present work, different natural compounds from coffee by-product extracts (coffee silverskin and spent coffee) rich in polyphenols, was investigated against beauvericin (BEA) induced-cytotoxicity on SH-SY5Y cells. Spent coffee arise as waste products through the production of instant coffee and coffee brewing; while the silverskin is a tegument which is removed and eliminated with toasting coffee grains. First of all, polyphenol extraction methods, measurement of total polyphenols content and its identification were carried out. Afterwards evaluating in vitro effects with MTT assay on SH-SY5Y cells of coffee by-product extracts and mycotoxins at different concentrations and …

0106 biological sciencesSH-SY5YToxicologyCoffee01 natural sciencesAntioxidantsNeuroblastoma03 medical and health scienceschemistry.chemical_compoundChlorogenic acidCell Line TumorDepsipeptidesHumansMTT assayFood scienceMycotoxinBiological Products0303 health sciencesPlant ExtractsChemistrybusiness.industry010604 marine biology & hydrobiology030302 biochemistry & molecular biologyfood and beveragesMycotoxinsBeauvericinCell culturePolyphenolBrewingbusinessToxicon
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Simultaneous determination of nine phytohormones in seaweed and algae extracts by HPLC-PDA.

2016

An RP-HPLC-PDA method for the simultaneous analysis of 9 compounds deriving from the phytohormones class was developed and optimized, namely indoleacetic acid (IAA), indolebutyric acid (IBA), phenyleacetic acid (PAA), naphtyleacetic acid (NAA), trans-zeatin (TZ), kinetin (KA), isopentenyladenine (IA), 6-benzylaminopurine (6-BA) and abscisic acid (ABA). Validation of the method was performed on the SFE-CO2 extract made out of the mixture of Baltic algae. The regression coefficients for plant hormones were in the range from 0.997 to 0.999. The LOD and LOQ were on the levels from 0.05–0.29 and 0.15–0.88 mg/L, respectively. Developed method was used for the separation and determination plant ho…

0106 biological sciencesSeaweed extractsClinical Biochemistry01 natural sciencesBiochemistryAnalytical ChemistrySFE-CO2 seaweed extractchemistry.chemical_compoundAlgaePlant Growth RegulatorsChlorophytaCladophora glomerataSpirulinaHplc pdaBiomassOrganic ChemicalsAbscisic acidChromatography High Pressure LiquidChromatography Reverse-PhaseChromatographybiology010401 analytical chemistryHormones levelsSolid Phase ExtractionSupercritical fluid extractionRP-HPLC-PDACell BiologyGeneral Medicinebiology.organism_classificationSeaweed0104 chemical sciencesPhytohormoneschemistryRegression AnalysisKinetinIndolebutyric Acid010606 plant biology & botanyJournal of chromatography. B, Analytical technologies in the biomedical and life sciences
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Effect of pH on malolactic fermentation in southern Italian wines

2018

This study investigated the influence of pH on malolactic fermentation (MLF) in white wines (adjusted to pH 3.2, 3.4 and 3.8, respectively) from Falanghina grapes and red wines (adjusted to pH 3.4 and 3.8, respectively) from Tintilia grapes. The wines were inoculated with Oenococcus oeni and Lactobacillus plantarum strains, and a mix of them (50:50), in red Tintilia only. The time required to complete MLF in wines from white Falanghina grapes at pH 3.4 and 3.8 was lower with O. oeni, while MLF did not occur at pH 3.2. In red Tintilia, MLF was always completed within 35 days; at high pH (3.8) a significant increase in histamine was detected, while the decrease in citric acid concentration ca…

0106 biological sciencesSensorial analysisOrganolepticBerry01 natural sciencesBiochemistryIndustrial and Manufacturing Engineeringchemistry.chemical_compoundCitric acid0404 agricultural biotechnology010608 biotechnologyCitric acid; Histamine; Malolactic fermentation; pH; Sensorial analysis; Biotechnology; Food Science; Chemistry (all); Biochemistry; Industrial and Manufacturing EngineeringMalolactic fermentationFood scienceOenococcus oenibiologyChemistrypHMalolactic fermentationChemistry (all)food and beverages04 agricultural and veterinary sciencesGeneral ChemistrySettore AGR/15 - Scienze E Tecnologie Alimentaribiology.organism_classificationSensorial analysi040401 food scienceCitric acidLactobacillus plantarumHistamineBiotechnologyFood Science
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