Search results for " Bone"
showing 10 items of 933 documents
Mathematical modeling of fetal limb growth
1989
Using ultrasound measurements of the femur, tibia, humerus, radius (N = 515), and fibula and ulna (N = 385) from normal fetuses between 12 and 40 completed weeks of gestation, growth models were determined for each bone by computer analysis. On the basis of residual analysis, growth of fetal limb bones could best be expressed as a function of tangens hyperbolicus. Growth profiles and growth data are shown with 5th, 10th, 50th, 90th, and 95th percentiles. These results are compared with previous investigations of limb bone measurements.
High-Temperature Sintering of Xenogeneic Bone Substitutes Leads to Increased Multinucleated Giant Cell Formation: In Vivo and Preliminary Clinical Re…
2014
The present preclinical and clinical study assessed the inflammatory response to a high-temperature–treated xenogeneic material (Bego-Oss) and the effects of this material on the occurrence of multinucleated giant cells, implantation bed vascularization, and regenerative potential. After evaluation of the material characteristics via scanning electron microscopy, subcutaneous implantation in CD-1 mice was used to assess the inflammatory response to the material for up to 60 days. The clinical aspects of this study involved the use of human bone specimens 6 months after sinus augmentation. Established histologic and histomorphometric analysis methods were applied. After implantation, the mat…
Foreign Body Giant Cell–Related Encapsulation of a Synthetic Material Three Years After Augmentation
2016
Bone substitute materials of different origin and chemical compositions are frequently used in augmentation procedures to enlarge the local bone amount. However, relatively little data exist on the long-term tissue reactions. The presented case reports for the first time histological and histomorphometrical analyses of a nanocrystaline hydroxyapatite–based bone substitute material implanted in the human sinus cavity after an integration period of 3 years. The extracted biopsy was analyzed histologically and histomorphometrically with focus on the tissue reactions, vascularization, new bone formation, and the induction of a foreign body reaction. A comparably high rate of connective tissue (…
Advanced Glycation End Products: Do They Impair Bone Health in Diabetes?
2022
AbstractIn diabetes mellitus (DM), there is increased formation and accumulation of advanced glycation end products (AGEs), which represent a heterogeneous class of molecules produced by non-enzymatic glycation of various molecules during long-term hyperglycaemia. Several studies have examined the role of AGEs in DM complications. Accumulating evidence suggests that AGEs affect bone metabolism. New knowledge indicates that they may play a role in bone disease among DM subjects. More data are now needed to clarify their role and to explore new AGEs-based therapeutic options for optimal bone health in DM.
What grafting materials produce greater alveolar ridge preservation after tooth extraction? A systematic review and network meta-analysis
2021
Abstract A systematic review and network meta-analysis was conducted to compare different bone-substitute materials used for alveolar ridge preservation after tooth extraction. The electronic search was carried out on Embase, PubMed, Cochrane Library, Web of Science, Scopus, LILACS, and grey literature up to March 22, 2020 (registration number INPLASY202030005). Only randomized controlled trials were included to answer the following PICOS question: ‘What grafting materials produce greater alveolar ridge preservation after tooth extraction?’ The primary outcomes were the alveolar width resorption 1 mm below the alveolar crest and buccal height resorption in millimeters. Of the 4379 studies i…
NEW GUIDED BONE REGENERATION PROCEDURE USING LEUKOCYTE AND PLATELET RICH FIBRIN (L PRF) IN ORAL SURGERY
2021
Non-transfusional hemocomponents are autogenous products used in several surgical fields obtained by the centrifugation of a blood sample from a patient and able to promote hard and soft tissue regeneration, local haemostasis, and the acceleration of wound healing. The aim of this PhD thesis was the validation of an innovative protocol for the Guided Bone Regeneration (GBR) technique using second-generation autologous platelet concentrates, Leukocytes and Platelet-rich Fibrin (L-PRF), in post-extraction sockets of patients in need of dental avulsions and successive implant prosthetic rehabilitation, evaluating its ability to prevent alveolar bone resorption and promote bone regeneration. Th…
Coded Excitation of the Fundamental Flexural Guided Wave in Coated Bone Phantoms
2017
There is an increasing interest of using ultrasonic guided waves to assess long cortical bones. In particular, a method of ultrasonic estimation of cortical thickness based on the fundamental flexural guided wave (FFGW), generally consistent with the A0 Lamb mode, has proven to be promising in vitro and modeling studies. Soft-tissue coating on top of the bone makes, however, the related in vivo application challenge. Visibility of FFGW on top of the soft tissue is not good due to the characteristic displacement profile of this mode, and due to its relatively high attenuation in the bone and surrounding tissue. Moreover, the soft tissue provides a direct propagation path for ultrasonic modes…
Adherence to Guidelines among Italian Urologists on Imaging Preoperative Staging of Low-Risk Prostate Cancer: Results from the MIRROR (Multicenter It…
2011
Objective. A number of evidence-based guidelines for diagnosis and management of prostate cancer have been published. The aim of this study is to evaluate the adherence of Italian urologists to the guidelines concerning the preoperative imaging staging of prostate cancer.Methods. In October 2007 a multicentric observational perspective study called Multicentric Italian Report on Radical prostatectomy Outcome and Research (MIRROR) was started in 135 Italian urology centers. Recruitment was closed in December 2008 and 2,408 cases were collected. In this paper we have taken into consideration all examinations carried out for preoperative imaging staging, evaluating compliance with the recommen…
Ein Beitrag zur metrischen Geschlechtsdiagnose verbrannter und unverbrannter menschlicher Knochenreste?ausgearbeitet an der Pars petrosa ossis tempor…
1981
Die vorliegende Arbeit prasentiert eine neue Methode zur Geschlechtsdiagnose, eine uni-, di- und multivariate Analyse der Pars petrosa, eines Teiles des Schlafenbeines — angeregt durch das haufige Auftreten dieser Struktur in Leichenbranden. Wie der Vergleich der Irrtumswahrscheinlichkeiten zweier Diskriminanzfunktionen zeigt, erweist sich die Einbeziehung aller erhobenen Variablen als vorteilhaft. Schon die Berucksichtigung von nur drei Masen fuhrt zu einer geringeren Fehlerquote bei der Geschlechtszuweisung als bei einigen konventionellen Verfahren. Abschliesend wird das Problem der Schrumpfung fur die Ubertragbarkeit der Methode auf Leichenbrandmaterial erortert, und schrumpfungskorrigie…
Mortalit�t, Morbidit�t und funktionelles Endergebnis nach "Open-book-Verletzungen" und lateralen Kompressionsverletzungen des Beckenringes
2003
In einer retrospektiven Studie wurden die Begleitverletzungen, Behandlungsmerkmale, Morbiditat, Mortalitat und das radiologische und funktionelle Endergebnis von 222 Patienten mit einer Beckenringverletzung vom Typ B oder vom Typ C nach der Klassifikation von M.Tile eruiert. 52 Patienten wiesen eine "Open-book-Verletzung" auf (Typ B1), 48 Patienten eine laterale Kompressionsverletzung (Typ B2/B3), 122 Patienten wiesen eine C-Verletzung auf. Die Zahl der neurologischen bzw.urologischen Begleitverletzungen lag bei den B1-Patienten mit 21% bzw. 9,6% deutlich hoher als bei den B2/B3 Patienten mit 12% bzw.2,1%.66% der Patienten mit einer B-Verletzung wurden mit einem Fixateur externe entversorgt…