Search results for " CYTOGENETICS"

Preliminary data on cytogenetics and cytotaxonomy of Cercopithecus albogoularis labiatus (Samango monkey)

2010

Preliminary data on cytogenetics and cytotaxonomy of Cercopithecus albogoularis labiatus (Samango monkey) L. Sineo1, M. Roccella1, B. Picone1, R. Stanyon2, F. Genin3 and J. Masters 3 1Dipartimento di Biologia animale, Università di Palermo, Italia; 2Dipartimento di Biologia evoluzionistica, Università di Firenze, Italia; 3Department of Zoology and Entomology, University of Fort Hare, Alice, South Africa The systematic status and phylogenetic relationships of the C. mitis “species group” are contentious. The species group effectively includes very different species (C. nictitans, C. mitis, and C. albogularis) with wide, reciprocally remote distribution in Africa, and high regional variabilit…

The Evolution of Human Chromosome 7 Syntenies in Eutheria, with Special Attention to Primates

2004

Genetic and cytogenetic comparison in between man and non-human primates has largely contributed to the knowledge of the evolution of the Order Primates, and in particular of man. Recently, the "Chromosome painting" approach indicated a strong conservation of syntenies in Eutheria. At present, a more precise identification of breakpoints and evolutionary related rearrangements can be obtained by BAC and locus specific in situ hybridi- sation. In spite to this situation the evolutionary history of different human autosomes remains a dilemma; at the same time, high resolution banded chromosome analysis confirms to be a valuable tool for the preliminary detection of fine rearrangements. This r…

Chromosome painting of the pygmy tree shrew shows that no derived cytogenetic traits link primates and scandentia.

2012

We hybridized human chromosome paints on metaphases of the pygmy tree shrew (<i>Tupaia minor</i>, Scandentia). The lack of the ancestral mammalian 4/8 association in both Primates and Scandentia was long considered a cytogenetic landmark that phylogenetically linked these mammalian orders. However, our results show that the association 4/8 is present in <i>Tupaia </i>along with not previously reported associations for 1/18 and 7/10. Altogether there are 11 syntenic associations of human chromosome segments in the pygmy tree shrew karyotype: 1/18, 2/21, 3/21, 4/8, 7/10, 7/16, 11/20, 12/22 (twice), 14/15 and 16/19. Our data remove any cytogenetic evidence that Scandent…

Testing the uncertain phylogenetic position of Daubentonia madagascariensis (Strepsirhines) using chromosomes

2011

Exploring Evolution in Ceboidea (Platyrrhini, Primates) by Williams-Beuren Probe (HSA 7q11.23) Chromosome Mapping

2007

The ancestral platyrrhine karyotype was characterised by a syntenic association of human 5 and a small segment of human 7 orthologues. This large syntenic association has undergone numerous rearrangements in various phylogenetic lines. We used a locus-specific molecular cytogenetic approach to study the chromosomal evolution of the human 7q11.23 orthologous sequences (William-Beuren syndrome, WS) in various Ceboidea (Platyrrhini) species. The fluorescent in situ hybridisation of the WS probe revealed a two-way pattern of chromosomal organisation that suggests various evolutionary scenarios. The first pattern (seen in Callimico and Saimiri ) includes a fairly simple disruption of the 7/5 syn…

Centromeric enrichment of LINE-1 retrotransposon in two species of South American monkeys Alouatta belzebul and Ateles nancymaae (Platyrrhini, Primat…

2022

LINE-1 sequences have been linked to genome evolution, plasticity and speciation; however, despite their importance, their chromosomal distribution is poorly known in primates. In this perspective, we used fluorescence in situ hybridization (FISH) to map LINE-1 probes onto two representative platyrrhine species, Aotus nancymaae (Cebidae) and Alouatta belzebul (Atelidae), both characterized with highly rearranged karyotypes, in order to investigate their chromosomal distribution and role and to better characterize the two genomes. We found centromeric enrichment of LINE-1 sequences on all biarmed and acrocentric chromosomes co-localized with heterochromatin C-positive bands. This distributio…

L’IMPIEGO DELLA MORFOMETRIA GEOMETRICA E IL CONTRIBUTO DELLA CITOGENETICA NELLO STUDIO DELLA TRIBÙ CERCOPITHECINI (ORDINE PRIMATES)

The tribe Cercopithecini is a large and colourful taxon of African primates. Together with the tribe Papionini, it belongs to the subfamily Cercopithecinae (Gray, 1821). Despite several studies carried on the present species of Cercopithecini (guenons and sister genera), up to date a strong and clear systematics is missing. The evolutionary relationships inside the tribe are controversial, as are the numbers of genera and species. This lack prevents our full comprehension of the evolution of the tribe. We decided to investigate the tribe Cercopithecini through the use of two methodologies: geometric morphometrics and cytogenetics. The geometric morphometric survey was conducted on 1126 cran…

Mapping the Wolf-Hirschhorn (wp 4p16.3) Locus on non-human primates

2008

MOLECULAR CYTOGENETIC APPROACH BY WOLF-HIRSCHHORN PROBE-MAPPING AND OTHERS BAC PROBES TO STUDY GENOME EVOLUTION IN PRIMATES

2009

Burkitt lymphoma with a granulomatous reaction: an M1/Th1‐polarised microenvironment is associated with controlled growth and spontaneous regression

2021

Aims Burkitt lymphoma (BL) is an aggressive B-cell lymphoma that, in some instances, may show a granulomatous reaction associated with a favourable prognosis and occasional spontaneous regression. In the present study, we aimed to define the tumour microenvironment (TME) in four such cases, two of which regressed spontaneously. Methods and results All cases showed aggregates of tumour cells with the typical morphology, molecular cytogenetics and immunophenotype of BL surrounded by a florid epithelioid granulomatous reaction. All four cases were Epstein-Barr virus (EBV)-positive with type I latency. Investigation of the TME showed similar features in all four cases. The analysis revealed a p…