Search results for " Cell"

showing 10 items of 14074 documents

Dendritic cell metabolism: moving beyond in vitro-culture-generated paradigms

2021

Dendritic cells (DCs) are key orchestrators of immunity and tolerance. It has become evident that DC function can be influenced by cellular metabolic programs. However, conclusions from early metabolic studies using in vitro GM-CSF DC cultures fail to correlate with bona fide DC populations. Here, we discuss the existing paradigms in the DC metabolism field, focusing on the limitations of the models utilized. Furthermore, we introduce alternative models to generate DCs in vitro that better emulate DCs found in vivo. Finally, we highlight new techniques to evaluate DC metabolism at the single-cell level. The combination of these two strategies could help advance the DC metabolism field towar…

0106 biological sciences0303 health sciencesBiomedical EngineeringCell DifferentiationBioengineeringDendritic CellsDendritic cellBiology01 natural sciencesIn vitro03 medical and health sciencesIn vivo010608 biotechnologyNeuroscienceFunction (biology)030304 developmental biologyBiotechnologyCurrent Opinion in Biotechnology
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Chenopodium album L. (Fat Hen): In Vitro Cell Culture, and Production of Secondary Metabolites (Phytosterols and Ecdysteroids)

1998

The name Chenopodium is derived from the Greek words chenos (goose) and podos (foot), because the leaves often resemble goose feet. This genus consists of ca. 120 species, widely distributed over the world, 45 of which have been described in India.

0106 biological sciences0303 health sciencesbiologyChenopodium[SDV]Life Sciences [q-bio]Mevalonic acidbiology.organism_classification01 natural sciences[SDV] Life Sciences [q-bio]03 medical and health scienceschemistry.chemical_compoundGoosechemistryGenusbiology.animalBotanyComputingMilieux_MISCELLANEOUSIn vitro cell culture030304 developmental biology010606 plant biology & botany
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Intracellular compartmentation and plant cell signalling

1997

Compartmentation is an essential feature of eukaryotic cells, and is crucial for the regulation of cell metabolism. Recent progress has significantly improved the understanding of signal transduction pathways in plants, including the activation of light-signalling networks and the tightly controlled generation of the calcium message. Cell compartmentation is important for the regulation and proliferation of these signalling processes.

0106 biological sciences0303 health scienceschemistry.chemical_elementPlant ScienceBiologyCalciumPlant cell01 natural sciencesIntracellular compartmentationElicitorCell biology03 medical and health sciencesSignallingCell metabolismBiochemistrychemistryCell Compartmentation[SDV.BV]Life Sciences [q-bio]/Vegetal Biology[SDV.BV] Life Sciences [q-bio]/Vegetal BiologySignal transduction030304 developmental biology010606 plant biology & botany
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Manipulating Individual Decisions and Environmental Conditions Reveal Individual Quality in Decision-Making and Non-Lethal Costs of Predation Risk

2012

Received: July 6, 2012; Accepted: November 13, 2012; Published: December 13, 2012

0106 biological sciencesAnimal breedingEcophysiology01 natural sciencesNesting BehaviorPredationSongbirdsBehavioral EcologyOrnithologyMolecular Cell BiologyCellular Stress ResponsesAnimal Managementmedia_common0303 health sciencesMultidisciplinaryEcologyAnimal BehaviorEcologyReproductionPhysiological conditionQRCommunity EcologyHabitatMedicineFemaleResearch ArticleOffspringSciencemedia_common.quotation_subjectDecision MakingEnvironmentBiology010603 evolutionary biologyBirds03 medical and health sciencesAnimalsQuality (business)BiologyCommunity StructureEcosystemSelection (genetic algorithm)030304 developmental biologyEvolutionary BiologyReproductive successHawksSpecies InteractionsEvolutionary EcologyPredatory Behaviorta1181Veterinary ScienceZoologyPLoS One
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Anti-Inflammatory and Cytoprotective Effect of Plant Sterol and Galactooligosaccharides-Enriched Beverages in Caco-2 Cells

2019

Plant sterol (PS) (1 g/100 mL) enriched milk-based fruit beverages with or without galactooligosaccharides (GOS) (1.8 g/100 mL) were used in differentiated Caco-2 cells. Their potential cytopreventive effect against oxidative stress induced by cholesterol oxidation products (COPs) and their anti-inflammatory properties were evaluated. Preincubation (24 h) with bioaccessible fractions from beverages without and with GOS (MfB and MfB-G) completely prevented the COPs (60 μM/4 h) induced oxidative stress independent to GOS presence with exception to calcium influx and GSH content, where a partial protective effect was observed. Besides, MfB produced a significant (p < 0.05) reduction of IL-8 (4…

0106 biological sciencesAntioxidantmedicine.drug_classmedicine.medical_treatmentInterleukin-1betaAnti-Inflammatory AgentsOligosaccharidesChromosomal translocationProtective Agentsmedicine.disease_cause01 natural sciencesAnti-inflammatoryBeverageschemistry.chemical_compoundmedicineHumansFood scienceCholesterol010401 analytical chemistryTranscription Factor RelAPhytosterolsGeneral ChemistryGlutathionePlant sterol0104 chemical sciencesOxidative StresschemistryCytoprotectionCaco-2Caco-2 CellsGeneral Agricultural and Biological SciencesOxidative stress010606 plant biology & botanyJournal of Agricultural and Food Chemistry
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Involvement of the glutamate receptor AtGLR3.3 in plant defense signaling and resistance toHyaloperonospora arabidopsidis

2013

Like their animal counterparts, plant glutamate receptor-like (GLR) homologs are intimately associated with Ca(2+) influx through plasma membrane and participate in various physiological processes. In pathogen-associated molecular patterns (PAMP)-/elicitor-mediated resistance, Ca(2+) fluxes are necessary for activating downstream signaling events related to plant defense. In this study, oligogalacturonides (OGs), which are endogenous elicitors derived from cell wall degradation, were used to investigate the role of Arabidopsis GLRs in defense signaling. Pharmacological investigations indicated that GLRs are partly involved in free cytosolic [Ca(2+)] ([Ca(2+)]cyt) variations, nitric oxide (N…

0106 biological sciencesArabidopsis thaliana[SDV]Life Sciences [q-bio]ArabidopsisOligosaccharidesPlant Science01 natural sciencesCALCIUM SIGNATURESchemistry.chemical_compoundGene Expression Regulation PlantSYSTEMIC ACQUIRED-RESISTANCEArabidopsisPlant defense against herbivoryArabidopsis thalianaPlant ImmunityGENE-EXPRESSIONCalcium signaling0303 health sciencesIMMUNE-RESPONSESTOBACCO CELLSfood and beveragesCYTOSOLIC CALCIUMElicitorOomycetesReceptors GlutamateBiochemistryHost-Pathogen Interactions[SDE]Environmental SciencesoligogalacturonidesSignal transductionSignal Transductionglutamate receptorHyaloperonospora arabidopsidisBiologyNitric Oxidecalcium signaling03 medical and health sciencesplant defenseGeneticsDNQX[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyBOTRYTIS-CINEREA030304 developmental biologyHyaloperonospora arabidopsidisNITRIC-OXIDEArabidopsis ProteinsCell Biologybiology.organism_classificationSALICYLIC-ACIDchemistryPLASMA-MEMBRANEReactive Oxygen Species010606 plant biology & botanyThe Plant Journal
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Interspecific comparison of the performance of soaring migrants in relation to morphology, meteorological conditions and migration strategies.

2012

This is an open-access article distributed under the terms of the Creative Commons Attribution License.-- et al.

0106 biological sciencesAtmospheric PhenomenaAtmospheric ScienceBiologialcsh:MedicineComputingMilieux_LEGALASPECTSOFCOMPUTING01 natural sciences010605 ornithologyBehavioral EcologyOrnithologyAfrica NorthernZoologiaMeteorological conditionsMigration strategiesSpatial and Landscape EcologyZoologíaBiomechanicsAtmospheric Dynamicslcsh:ScienceMultidisciplinarybiologyEcologyAnimal BehaviorEcologyPhysicsFlight speedBird flightSeasonsResearch ArticleEagleMorphologyeducationBiophysics010603 evolutionary biologyAltitudeMeteorologybiology.animalAtmospheric StructuresAnimalsBiologyVultureMigratory performance of birdsGlobal wind patternsRaptorslcsh:RInterspecific competitionEarth Sciences1182 Biochemistry cell and molecular biologyAnimal Migrationlcsh:QPhysical geographyScale (map)Zoology
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Anhydrobiosis in yeasts: Psychrotolerant yeasts are highly resistant to dehydration.

2018

Yeast cells are able to transition into a state of anhydrobiosis (temporary reversible suspension of metabolism) under conditions of desiccation. One of the most efficient approaches for understanding the mechanisms underlying resistance to dehydration-rehydration is to identify yeasts, which are stable under such treatments, and compare them with moderately resistant species and strains. In the current study, we investigated the resistance to dehydration-rehydration of six psychrotolerant yeast strains belonging to two species. All studied strains of Solicoccozyma terricola and Naganishia albida were found to be highly resistant to dehydration-rehydration. The viability of S. terricola str…

0106 biological sciencesBioengineeringBiology01 natural sciencesApplied Microbiology and BiotechnologyBiochemistryPermeabilityCell membrane03 medical and health sciences010608 biotechnologyYeastsGeneticsmedicinedehydration–rehydrationViability assayDesiccationCryptobiosis030304 developmental biology0303 health sciencesMicrobial ViabilityMicrobial ViabilityDehydrationCell MembraneMetabolismanhydrobiosisYeastanhydrobiosis; dehydration–rehydration; plasma membrane permeability; resistance to desiccation; Cell Membrane; Desiccation; Permeability; Yeasts; Dehydration; Microbial ViabilityMembranemedicine.anatomical_structureBiochemistryDesiccationplasma membrane permeabilityresistance to desiccationBiotechnologyYeast (Chichester, England)
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Characterization of MRNP34, a novel methionine-rich nacre protein from the pearl oysters

2012

9 pages; International audience; Nacre of the Pinctada pearl oyster shells is composed of 98% CaCO(3) and 2% organic matrix. The relationship between the organic matrix and the mechanism of nacre formation currently constitutes the main focus regarding the biomineralization process. In this study, we isolated a new nacre matrix protein in P. margaritifera and P. maxima, we called Pmarg- and Pmax-MRNP34 (methionine-rich nacre protein). MRNP34 is a secreted hydrophobic protein, which is remarkably rich in methionine, and which is specifically localised in mineralizing the epithelium cells of the mantle and in the nacre matrix. The structure of this protein is drastically different from those …

0106 biological sciencesBiomineralizationCalcifying mantleMethionine-richMolecular Sequence DataClinical BiochemistryGene ExpressionBiologyMatrix (biology)engineering.materialProteomics010603 evolutionary biology01 natural sciencesBiochemistryLow complexity03 medical and health sciencesPaleontologychemistry.chemical_compoundCalcification PhysiologicMethionineAnimalsAmino Acid SequencePinctada[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsNacre030304 developmental biology0303 health sciencesMethionineViral matrix proteinOrganic ChemistryProteinsEpithelial Cells[ SDV.IB.BIO ] Life Sciences [q-bio]/Bioengineering/Biomaterialsbiology.organism_classificationProtein Structure TertiarychemistryBiochemistryengineeringMolluscMatrix proteinPearlBiomineralizationPinctada
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Calcium homeostasis in plant cell nuclei

2009

International audience; In plant cells, calcium-based signaling pathways are involved in a large array of biological processes, including cell division, polarity, growth, development and adaptation to changing biotic and abiotic environmental conditions. Free calcium changes are known to proceed in a nonstereotypical manner and produce a specific signature, which mirrors the nature, strength and frequency of a stimulus. The temporal aspects of calcium signatures are well documented, but their vectorial aspects also have a profound influence on biological output. Here, we will focus on the regulation of calcium homeostasis in the nucleus. We will discuss data and present hypotheses suggestin…

0106 biological sciencesCELL NUCLEUSHOMEOSTASISAUTONOMYCell divisionPhysiologyAequorinchemistry.chemical_elementPlant ScienceCalcium01 natural sciencesCALCIUM03 medical and health sciencesCytosolPlant CellsOrganellemedicineCalcium SignalingCELLULE VEGETALE030304 developmental biologyCalcium metabolism0303 health sciencesbiologyAEQUORINEAEQUORINCell biology[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacymedicine.anatomical_structurechemistryHOMEOSTASIEbiology.proteinSignal transductionNucleusHomeostasis010606 plant biology & botanySignal Transduction
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