Search results for " Chemical Engineering"
showing 10 items of 2965 documents
Synthesis, Characterization, and Cytotoxicity of New Spirooxindoles Engrafted Furan Structural Motif as a Potential Anticancer Agent
2022
A new series of spirooxindoles based on ethylene derivatives having furan aryl moiety are reported. The new hybrids were achieved via [3 + 2] cycloaddition reaction as an economic one-step efficient approach. The final constructed spirooxindoles have four contiguous asymmetric carbon centers. The structure of 3a is exclusively confirmed using X-ray single crystal diffraction. The supramolecular structure of 3a is controlled by O···H, H···H, and C···C intermolecular contacts. It includes layered molecules interconnected weak C–H···O (2.675 Å), H···H (2.269 Å), and relatively short Cl···Br interhalogen interactions [3.4500(11)Å]. Using Hirshfeld analysis, the percentages of these intermolecul…
Optimizing the SYBR green related cyanine dye structure to aim for brighter nucleic acid visualization
2022
In recent years, the studies of RNA and its use for the development of RNA based vaccines have increased drastically. Although cyanine dyes are commonly used probes for studying nucleic acids, in a wide range of applications, there is still a growing need for better and brighter dyes. To meet this demand, we have systematically studied the structure of SYBR green-related cyanine dyes to gain a deeper understanding of their interactions with biomolecules especially how they interact with nucleic acids and the structural components which makes them strongly fluorescent. Herein, five new dyes were synthesized, and their photophysical properties were evaluated. Observations of photophysical cha…
Sustainable Biomass-Derived Carbon Electrodes for Potassium and Aluminum Batteries: Conceptualizing the Key Parameters for Improved Performance
2023
The development of sustainable, safe, low-cost, high energy and density power-density energy storage devices is most needed to electrify our modern needs to reach a carbon-neutral society by ~2050. Batteries are the backbones of future sustainable energy sources for both stationary off-grid and mobile plug-in electric vehicle applications. Biomass-derived carbon materials are extensively researched as efficient and sustainable electrode/anode candidates for lithium/sodium-ion chemistries due to their well-developed tailored textures (closed pores and defects) and large microcrystalline interlayer spacing and therefore opens-up their potential applications in sustainable potassium and alumin…
Extraction of lapachol from Tabebuia avellanedae wood with supercritical CO2: an alternative to Soxhlet extraction?
2003
The solubility of lapachol in supercritical CO2 was determined at 40°C and pressures between 90 and 210 bar. Supercritical fluid extraction of lapachol and some related compounds by CO2 from Tabebuia avellanedae wood is compared to Soxhlet extraction with different solvents. A standard macroscale (100-200 g wood) and a microscale (~10 mg wood) experimental setup are described and their results are compared. The latter involved direct spectrophotometric quantification in a high-pressure autoclave with an integrated optical path and a magnetic stirrer, fitted directly into a commercial spectrophotometer. The relative amount of lapachol extracted by supercritical CO2 at 40°C and 200 bar was ab…
Electrochemical properties of graphite/nylon electrodes additively manufactured by laser powder bed fusion
2023
Nowadays, additive manufacturing, known as 3D printing, is vigorously employed at various enterprises due to the ability of industrial series production and customization in conjunction with geometry freedom. While, material design and fabrication of composite materials, meeting the desired architecture and properties, is another promising application of additive manufacturing. For instance, additive manufacturing of the material exhibiting electrochemical properties is beneficial for the development of freestanding electrodes that might be used in electrochemical energy storage systems. Herein, the graphite/nylon composite with a high carbon ratio of 30 wt% was produced by laser powder bed…
Layered Double Hydroxides: A Toolbox for Chemistry and Biology
2019
Layered double hydroxides (LDHs) are an emergent class of biocompatible inorganic lamellar nanomaterials that have attracted significant research interest owing to their high surface-to-volume ratio, the capability to accumulate specific molecules, and the timely release to targets. Their unique properties have been employed for applications in organic catalysis, photocatalysis, sensors, drug delivery, and cell biology. Given the widespread contemporary interest in these topics, time-to-time it urges to review the recent progresses. This review aims to summarize the most recent cutting-edge reports appearing in the last years. It firstly focuses on the application of LDHs as catalysts in re…
Advances and Perspectives of Supercritical Fluid Technology
2013
1 Dipartimento di Ingegneria Industriale, Universita di Salerno, Salerno, 84084 Fisciano, Italy 2 Departamento de Ingenieŕia Quimica, Universidad de Castilla-La Mancha, 13004 Ciudad Real, Spain 3 Department of Agricultural, Food & Nutritional Sciences, University of Alberta, Edmonton, AB, Canada T6G 2P5 4Dipartimento di Ingegneria Chimica, Gestionale, Informatica, Meccanica, Universita di Palermo, 90128 Palermo, Italy
Enzyme Inhibition Microassays on Blu-Ray Disks for Drug Discovery
2019
[EN] An enzyme inhibition-based assay for drug discovery developed by microarraing on Blu-ray disks is presented. As a proof-of-concept, the system screens a selected molecule library of potential chemical inhibitors against the glycoenzyme peroxidase, identifying the promising lead compounds with high selectivity using standard Blu-ray disks and drives. In order to face the first drug discovery stages, we establish the bases for a high-throughput screening assay and a methodology based on hypersurfaces suitable to manage a high number of data as well.
Thermal energy storage in granular deposits
2017
Energy storage technology is crucial for the development of the use of renewable energy sources. This is a substantial constraint, however it can, to some extent, be solved by storing energy in its various forms: electrical, mechanical, chemical and thermal. This article presents the results of research in thermal properties of granular deposits. Correlation between temperature changes in the stores over a period of time and their physical properties has been studied. The results of the research have practical application in designing thermal stores based on bulk materials and ground deposits. Furthermore, the research results are significant for regeneration of the lower ground sources for…
Internal heat gain from different light sources in the building lighting systems
2017
EU directives and the Construction Law have for some time required investors to report the energy consumption of buildings, and this has indeed caused low energy consumption buildings to proliferate. Of particular interest, internal heat gains from installed lighting affect the final energy consumption for heating of both public and residential buildings. This article presents the results of analyses of the electricity consumption and the luminous flux and the heat flux emitted by different types of light sources used in buildings. Incandescent light, halogen, compact fluorescent bulbs, and LED bulbs from various manufacturers were individually placed in a closed and isolated chamber, and t…