Search results for " Contri"

showing 10 items of 169 documents

Associations of non-Hodgkin Lymphoma (NHL) risk with autoimmune conditions according to putative NHL loci.

2015

Autoimmune conditions and immune system-related genetic variations are associated with risk of non-Hodgkin lymphoma (NHL). In a pooled analysis of 8,692 NHL cases and 9,260 controls from 14 studies (1988-2007) within the International Lymphoma Epidemiology Consortium, we evaluated the interaction between immune system genetic variants and autoimmune conditions in NHL risk. We evaluated the immunity-related single nucleotide polymorphisms rs1800629 (tumor necrosis factor gene (TNF) G308A), rs1800890 (interleukin-10 gene (IL10) T3575A), rs6457327 (human leukocyte antigen gene (HLA) class I), rs10484561 (HLA class II), and rs2647012 (HLA class II)) and categorized autoimmune conditions as prim…

LymphomaEpidemiologyOriginal Contributionstumor necrosis factorFollicular lymphomaNon-HodgkininteractionSingle-nucleotide polymorphismHuman leukocyte antigenmedicine.disease_causePolymorphism Single NucleotideAutoimmune DiseaseMedical and Health SciencesMathematical SciencesAutoimmunityAutoimmune DiseasesRare Diseasesimmune system diseasesHLA Antigenshuman leukocyte antigenhemic and lymphatic diseasesGenotypemedicineGeneticsHumans2.1 Biological and endogenous factorsPolymorphismAetiologyCancerbusiness.industryTumor Necrosis Factor-alphaLymphoma Non-HodgkinInflammatory and immune systemautoimmune conditionsOdds ratioSingle NucleotideHematologymedicine.diseaseAutoimmune conditions - risk of non-Hodgkin lymphoma (NHL)LymphomaInterleukin-10Case-Control StudiesImmunologyHIV/AIDSbusinessDiffuse large B-cell lymphomaenvironment
researchProduct

Evidence of a significant vitamin D deficiency among 9–13-year-old Polish children: results of a multicentre study

2018

Purpose To evaluate the extent to which the population of Polish preadolescents is vitamin D deficient and to assess seasonal variations in vitamin D status. Participants and methods A total of 720 healthy children aged 9–13 years (409 girls, 311 boys) residing in 6 representative geographical locations in Poland were studied. A parental-assisted questionnaire provided data on nutritional habits, vitamin D supplements and sun exposure. Serum concentration of 25-hydroxyvitamin was determined twice, after the winter in March and after the summer in October. Results In March, vitamin D deficiency (25–50 nmol/L) was found in 64%, and severe deficiency (< 25 nmol/L) in 20.2% of children. In Octo…

Male0301 basic medicinePediatricsmedicine.medical_specialtyAdolescentPopulationMedicine (miscellaneous)030209 endocrinology & metabolismPreadolescentsvitamin D deficiency03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesVitamin D and neurologyHumansMedicineChildeducationChildreneducation.field_of_study030109 nutrition & dieteticsNutrition and DieteticsVitamin D deficiencybusiness.industryOriginal ContributionSeasonalitySerum concentrationmedicine.disease25-Hydroxyvitamin D concentrationFish <Actinopterygii>FemalePolandSeasonsSun exposurebusinessEuropean Journal of Nutrition
researchProduct

Heterogeneity of executive functions among preschool children with psychiatric symptoms

2019

The aim of the present study was to investigate associations between internalizing and externalizing symptoms and deficits in executive functions (EF) as well as to examine the overall heterogeneity of EFs in a sample of preschool children attending a psychiatric clinic (n = 171). First, based on cut-off points signifying clinical levels of impairment on the parent-completed Child Behavior Checklist (CBCL), children were assigned into groups of internalizing, externalizing, combined or mild symptoms and compared to a reference group (n = 667) with regard to day care teacher ratings of EFs on the Attention and Executive Function Rating Inventory-Preschool (ATTEX-P). Second, latent profile an…

MaleCHILDHOODCBCLDay careExecutive functionsExecutive FunctionCOGNITIVE CONTROLDevelopmental and Educational PsychologyChild and adolescent psychiatryEFFORTFUL CONTROLTEACHER RATINGSChild Behavior ChecklistChildReference groupinternalizing symptomsPsychopathologyATTENTION-DEFICIT/HYPERACTIVITY DISORDERMental Disorders05 social sciencesExternalizing symptomsGeneral MedicineOriginal ContributionlastenpsykiatriaExecutive functionsexecutive functionspsychopathologyPsychiatry and Mental healthChild PreschoolInternalizing symptomsFemalePsychologypsykopatologia050104 developmental & child psychologyPsychopathologymedicine.medical_specialtytoiminnanohjaus (psykologia)PERFORMANCE-BASED MEASURES515 PsychologyINHIBITION050105 experimental psychologypreschoolexternalizing symptomsWORKING-MEMORYmedicineHumans0501 psychology and cognitive sciencesPsychiatrySet (psychology)PreschoolSELF-REGULATIONesikouluikäisetPediatrics Perinatology and Child Health
researchProduct

Early adolescent aggression predicts antisocial personality disorder in young adults : a population-based study

2018

Modestly prevalent in the general population (~ 4%), but highly prevalent in prison populations (> 40%), the diagnosis of antisocial personality disorder (ASPD) involves aggression as one of several possible criteria. Using multiple informants, we aimed to determine if general aggression, as well as direct and indirect subtypes, assessed in early adolescence (ages 12, 14) predict young adulthood ASPD in a population-based sample. Using data from a Finnish population-based longitudinal twin cohort study with psychiatric interviews available at age 22 (N = 1347), we obtained DSM-IV-based ASPD diagnoses. Aggression measures from ages 12 (parental and teacher ratings) and 14 (teacher, self, and…

MaleaggressiivisuusCHILDHOODALCOHOLAntisocial personality disorderPopulation-based3124 Neurology and psychiatryCohort Studies0302 clinical medicineantisocial personality disordernuoretDevelopmental and Educational PsychologyChild and adolescent psychiatryYoung adultChildeducation.field_of_study05 social sciencesaggressionPSYCHIATRIC-DISORDERSPSYCHOPATHOLOGYOriginal ContributionGeneral Medicine16. Peace & justicePREVALENCEDiagnostic and Statistical Manual of Mental DisordersAggressionPsychiatry and Mental healthConduct disorderFemalemedicine.symptomPsychologyBEHAVIOR050104 developmental & child psychologyPsychopathologyClinical psychologypsychiatric predictionmedicine.medical_specialtyAdolescent515 PsychologyPopulationTWINNATIONAL EPIDEMIOLOGIC SURVEY03 medical and health sciencesmielenterveyshäiriötmental disordersPsychiatric predictionmedicineHumans0501 psychology and cognitive scienceseducationnuoret aikuisetAggressionAntisocial personality disorderennusteetOdds ratiomedicine.diseaseELEMENTARY-SCHOOL030227 psychiatrypopulation-basedadolescentCONDUCT DISORDERPediatrics Perinatology and Child Healthpoikkeava käyttäytyminen
researchProduct

Identification of calcium sensing receptor (CaSR) mRNA-expressing cells in normal and injured rat brain

2009

Calcium sensing receptor (CaSR), isolated for the first time from bovine and human parathyroid, is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expr…

Malemedicine.medical_specialtyTime FactorsCentral nervous systemHippocampusCell CountSettore BIO/11 - Biologia MolecolareBiologySettore BIO/09 - Fisiologiachemistry.chemical_compoundSeizuresInternal medicineSettore BIO/10 - BiochimicaCaSRmedicineAnimalsRNA MessengerRats WistarIbotenic AcidMolecular BiologyIn Situ HybridizationNeuronsKainic AcidGeneral NeuroscienceDentate gyrusBrainColocalizationImmunohistochemistryRatsOligodendrogliamedicine.anatomical_structureEndocrinologynervous systemchemistryBrain InjuriesNeurogliaNeurology (clinical)Pyramidal cellCaSR; BrainCalcium sensing receptor (CaSR) isolated for the first time from bovine and human parathyroid is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expression in neurons and oligodendrocytes whereas it was not found expressed both in the microglia and in astrocytes. One week after kainate-induced seizure CaSR was found in the injured CA3 region of the hippocampus and very interestingly it was found up-regulated in the neurons of CA1-CA2 and dentate gyrus. Similarly 1 week following ibotenic acid injection in the hippocampus CaSR mRNA expression was increased in oligodendrocytes both in the lesioned area and in the contralateral CA1-CA3 pyramidal cell layers and dentate gyrus. One week after needle-induced mechanical lesion an increase of labeled cells expressing CaSR mRNA was observed along the needle track. In conclusion the present results contribute to extend available data on cell type-expressing CaSR in normal and injured brain and could spur to understand the role of CaSR in repairing processes of brain injury.Receptors Calcium-SensingIbotenic acidDevelopmental BiologyAstrocyte
researchProduct

L’inclusione vista dagli alunni: costruzione e validazione del questionario per rilevare la qualità inclusiva della scuola

2018

Molti studi nazionali e internazionali si sono concentrati sulla valutazione e sulla promozione della qualità inclusiva della scuola. Si tratta di un argomento complesso, che ha stimolato un ampio dibattito e una varietà di contributi che mettono in luce la necessità di uno strumento in grado di misurare la qualità inclusiva delle nostre scuole, per determinare l’evidenza empirica riguardo a questo tema. L’articolo presenta i risultati di una sperimentazione finalizzata alla redazione di un questionario per la rilevazione della qualità inclusiva del sistema scolastico percepita dagli alunni. Il questionario si pone come uno strumento di valutazione e autovalutazione che permette la misurazi…

Many national and international studies have concentrated on the evaluation and promotion of the inclusive qualities of schools. It is a complex issue which has led to wide debate and a variety of contributions which in turn highlight the need for a tool capable of measuring the inclusive quality of our schools in order to determine the empirical evidence regarding this topic. This article presents the results of an experiment in drafting a questionnaire in order to measure the inclusive quality of the school system perceived by its pupils. The questionnaire is intended as an evaluation and selfevaluation tool that enables the inclusive quality generated by the context to be measured as it is perceived by pupils. At the same time the tool allows reflection processes amongst teachers to be promoted so that they can implement educational activities which contribute to the planning and control of inclusive teaching practices. This contribution puts forward an original tool for measuring the inclusive quality of the school system perceived by pupils attending primary school in several Sicilian towns. It was administered in its definitive version to a sample of 1652 children. The psychometric properties of the tool and the significance it can hold in the areas of planning in research and of educational design are presented in this paper.Settore M-PED/03 - Didattica E Pedagogia Speciale
researchProduct

Plasmon Excitations in Mixed Metallic Nanoarrays

2019

Features of the surface plasmon from macroscopic materials emerge in molecular systems, but differentiating collective excitations from single-particle excitations in molecular systems remains elusive. The rich interactions between single-particle electron-hole and collective electron excitations produce phenomena related to the chemical physics aspects within the atomic array. We study the plasmonic properties of atomic arrays of noble (Au, Ag, and Cu) and transition-metal (Pd, Pt) homonuclear chains using time-dependent density functional theory and their Kohn-Sham transition contributions. The response to the electromagnetic radiation is related to both the geometry-dependent confinement…

Materials scienceGeneral Physics and AstronomyFOS: Physical sciences02 engineering and technologyElectronoptiset ominaisuudet01 natural sciencesMolecular physicsElectromagnetic radiationHomonuclear moleculeplasmonicsnanorakenteet0103 physical sciencesMesoscale and Nanoscale Physics (cond-mat.mes-hall)Physics::Atomic and Molecular Clusterstransition contribution mapsGeneral Materials ScienceSurface plasmon resonance010306 general physicsPlasmonCondensed Matter - Materials ScienceCondensed Matter - Mesoscale and Nanoscale Physicsta114Surface plasmontiheysfunktionaaliteoriaGeneral EngineeringMaterials Science (cond-mat.mtrl-sci)molecular plasmonics021001 nanoscience & nanotechnologytime-dependent density-functional theorytime-dependent density functional theorycollective excitationQuasiparticleDensity functional theory0210 nano-technology
researchProduct

Photovoltaic facade: Comparison of actual technologies

2017

This article aims to establish the economic contribution of a photovoltaic system placed on a façade of a building, replacing traditional elements such as windows and glass-cement walls with active elements. The aim is to compare the behavior of next-generation systems, which favor architectonical integration, with traditional ones. Two novel systems have been taken into account: a dye sensitized solar cell (DSSC) and blue and grey thin film silicon panels. Different generation systems have been tested and compared in terms of efficiency and fill factor.

Materials scienceSilicon020209 energyPhotovoltaic systemEnergy Engineering and Power Technologychemistry.chemical_elementbuilding integrated photovoltaic02 engineering and technologySettore ING-INF/01 - ElettronicaEngineering physicsDye-sensitized solar cellchemistryPhotovoltaic module0202 electrical engineering electronic engineering information engineeringEconomic contributionFacadeFill factorDSSCElectrical and Electronic EngineeringThin filmthin film silicon2017 IEEE International Telecommunications Energy Conference (INTELEC)
researchProduct

The role of thermal contribution in the design of AA2024 friction stir welded butt and lap joints: mechanical properties and energy demand

2022

Although in recent times the use of solid-state welding processes as friction stir welding (FSW) has become increasingly widespread, for some joint morphologies, as lap joints, there are still signifcantly less data available on both process parameters optimization and energy consumption. In the present paper, the authors investigated the possibility of enhancing the joint quality in two diferent confgurations, i.e. lap and butt joints, taking into account specifc thermal contribution (STC) conferred to the weld. Strength, micro-hardness and microstructure were evaluated on the produced AA2024 aluminum alloys butt and lap joints. The surface response method (RSM) was used to investigate the…

Mechanical EngineeringFriction stir welding (FSW) · Response-surface methodology (RSM) · Specifc thermal contribution (STC) · Specifc energy consumption (SEC)Industrial and Manufacturing EngineeringProduction Engineering
researchProduct

I traffici illeciti nel Mediterraneo. Persone, stupefacenti, tabacco

2019

Attraverso la combinazione di ricerca criminologica e giuridico-normativa, e grazie anche alla collaborazione con esperti esterni (studiosi, magistrati, rappresentanti di istituzioni italiane e straniere), la ricerca da cui scaturisce il volume ha indagato le interazioni tra i diversi traffici illeciti e la criminalità organizzata nel bacino del Mediterraneo. In tale area, storicamente cruciale per la mobilità di persone e di beni, l’attenzione si è rivolta in particolare ai fenomeni del traffico e della tratta di persone, del traffico di stupefacenti e del contrabbando di sigarette. I contributi raccolti – unitamente al rapporto criminologico e ai cinque rapporti nazionali accessibili su w…

Mediterranean - Illicit Traffics - Smuggling of migrants - sostanze stupefacentiSettore IUS/16 - Diritto Processuale PenaleEste volumen es el resultado de la investigación bienal (2017-2019) "El nuevo Era del contrabando en el Mar Mediterráneo" financiado por el programa PYME - Impacto y gestionado por un equipo del Departamento de Derecho de la Universidad de Palermo compuesta por Vincenzo Militello (responsable de la científico) Alessandro Spena (coordinador) Annalisa Mangiaracina y Lycia syracuse. Mediante la combinación de investigaciones criminológicas y jurídico-normativas y gracias también a la colaboración con expertos externos (académicos magistrados representantes de instituciones italianas y extranjeras) la El proyecto investigó las interacciones entre los diferentes tipos de tráfico y de delito organizada en la cuenca del Mediterráneo. En esta área históricamente crucial para la movilidad de personas y bienes se ha prestado atención en particular a la los fenómenos de la trata y el contrabando de personas el tráfico de drogas y de contrabando de cigarrillos. Las contribuciones recogidas - junto con el informe criminológico y los cinco informes nacionales accesibles en www.unipa.it/nesmes.pmi y dedicado a los sistemas penales que se están investigando (Italia Alemania España Portugal Grecia) - pretenden proporcionar una visión profunda y variada del tema estudiado: el análisis y la reflexión socio-criminológica coexisten en él. legal (esto a su vez es tanto sustantivo como procesal) el estudio de las normas italianas y su colocación en una más amplio (europeo internacional pero también comparativo) el punto de vista del erudito y del magistrado. Surge la idea de que entre los tres tipos de tráfico considerado puede haber relaciones pragmáticas y estructurales a las que el los estados deberían dedicar más atención con vistas a un mayor contraste justo y eficaz como parte de un equilibrio entre la movilidad y la seguridad adecuado a la relevancia de la zona del Mediterráneo a nivel europeo y internacional.Settore IUS/17 - Diritto Penale
researchProduct