Search results for " DIAGNOSIS"

Detección precoz de la hipoacusia, influencia en el diagnóstico y en el tratamiento temprano

2021

Detección precoz de la hipoacusia, influencia en el diagnóstico y en el tratamiento temprano. INTRODUCCIÓN: La hipoacusia es el déficit sensorial mas frecuente en los países desarrollados. La prevalencia de cualquier grado de hipoacusia es de un 2-3 % de la población infantil y el 80% de las mismas, está presente al nacimiento. Los programa de screening auditivo (SA) se justifican por la alta incidencia de la hipoacusia y sus consecuencias devastadoras para el lenguaje cuando no se detecta precozmente. OBJETIVO: Establecer el número de niños diagnosticados de hipoacusia congénita gracias al SA en el hospital Universitario La Fe. Analizamos las técnicas utilizadas en el cribado, los parámetr…

Clinical and MRI measures to identify non-acute MOG-antibody disease in adults

2022

Abstract MRI and clinical features of myelin oligodendrocyte glycoprotein (MOG)-antibody disease may overlap with those of other inflammatory demyelinating conditions posing diagnostic challenges, especially in non-acute phases and when serologic testing for MOG antibodies is unavailable or shows uncertain results. We aimed to identify MRI and clinical markers that differentiate non-acute MOG-antibody disease from aquaporin 4 (AQP4)-antibody neuromyelitis optica spectrum disorder and relapsing remitting multiple sclerosis, guiding in the identification of patients with MOG-antibody disease in clinical practice. In this cross-sectional retrospective study, data from 16 MAGNIMS centres were i…

New Light on Parasorex Depereti (Erinaceomorpha: Erinaceidae: Galericini) from the Late Messinian (MN 13) of the Monticino Quarry (Brisighella, Faenz…

2019

Abstract A large-sized species of Parasorex is common in the MN 13 mammal assemblages from the uppermost Messinian sandy-marly fissure fillings within the Gessoso Solfifera Formation at Brisighella (Northern Apennine). This erinaceid has been classified as Galerix sp. in the first papers on the Brisighella fauna. Later, it was described in detail in an unpublished Ph.D. dissertation by Fanfani (1999), who referred it to Galerix depereti. Van den Hoek Ostende (2001) included G. depereti in the genus Parasorex, Parasorex depereti has been described by Crochet (1986) on scarce material from a few Early Pliocene (MN 14–15) localities of southern France and Spain. Parasorex cf. depereti has been…

Brenneria quercina and Serratia spp. isolated from Spanish oak trees Molecular characterization and development of PCR primers

2008

Brenneria quercina has been reported as one of the causal agents of oak decline in Spain. To investigate the bacterial variability of this pathogen from different Spanish oak forests, a collection of 38 bacterial isolates from seven geographic locations and from different oak species was analysed by sequencing 16S rDNA and rep-PCR fingerprinting. All Spanish isolates of B. quercina were grouped by rep-PCR into a homogenous cluster that differed significantly from B. quercina reference strains from California. 16S rDNA analysis revealed that 34 out of 38 isolates were Brenneria. However, four isolates belonged to the genus Serratia, suggesting that this bacterium could cause cankers in oak t…

Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample…

2022

This work was supported by funding from the European Community’s Seventh Framework Programme under grant agreement No. HEALTH-F2-2010-241909 (Project EU-GEI). (...) CA was supported by the Spanish Ministry of Science and Innovation; Instituto de Salud Carlos III (SAM16PE07CP1, PI16/02012, PI19/024), co-financed by ERDF Funds from the European Commission, ‘A way of making Europe’, CIBERSAM. Madrid Regional Government (B2017/BMD-3740 AGES-CM-2), Fundación Familia Alonso and Fundación Alicia Koplowitz. MB was supported by the Ministry of Economy and Competitivity (PI08/0208; PI11/00325; PI14/00612), Instituto de Salud Carlos III – ERDF Funds from the European Commission, ‘A way of making Europ…

A perioperative uncontrollable bleeding in an elderly patient with acquired hemophilia A: a case report

2013

Key Clinical Message Acquired hemophilia A should be taken into account in the differential diagnosis of perioperative bleeding in patients without any apparent reason for activated partial thromboplastin time prolongation.

Comparative Study of Feature classification Methods for Mass Lesion Recognition in Digitized Mammograms

2007

In this work a comparison of different classification methods for the identification of mass lesions in digitized mammograms is performed. These methods, used in order to develop Computer Aided Detection (CAD) systems, have been implemented in the framework of the MAGIC-5 Collaboration. The system for identification of mass lesions is based on a three-step procedure: a) preprocessing and segmentation, b) region of interest (ROI) searching, c) feature extraction and classification. It was tested on a very large mammographic database (3369 mammographic images from 967 patients). Each ROI is characterized by eight features extracted from a co-occurrence matrix containing spatial statistics inf…

Lipome du lobe profond de la glande parotide : à propos d'un cas rarissime

2006

The incidence of lipoma in the parotid gland is very low, and lipomas in the deep lobe of the parotid are extremely rare and seldom considered in the differential diagnosis of deep lobe parotid gland tumours. A deep lobe parotid gland lipoma is presented and discussed.

Isolated left ventricular non-compaction: A larger part of submerged iceberg with criteria for diagnosis to the limits of standard

2010

Implementation of a gene panel for the genetic diagnosis of primary ciliary dyskinesia

2020

Background: Primary ciliary dyskinesia (PCD) is a disease characterized by an alteration in the ciliary structure that causes an abnormal clearance of respiratory secretions. Its diagnosis is complex and is based on a combination of different techniques. The objective of this study was to design a gene panel including all known caustive genes, and to verify the utility for diagnostic in a cohort of Spanish patients. Methods: Multicenter cross-sectional study of patients with high suspicion of PCD, applying the criteria of the European Respiratory Society. Design a gene panel for mass sequencing with SeqCap EZ technology, including 44 PCD-related genes. Results: 79 patients were included, 53…