Search results for " DIP"
showing 10 items of 1273 documents
Considerations on the dipole moment of molecules forming the twisted intramolecular charge transfer state
1992
Several derivatives of dual-fluorescing dimethylaminobenzonitrile (DMABN) are compared regarding their ground and excited-state dipole moments extracted from electro-optical emission and solvatochromic measurements. The comparison includes bridged model compounds as well as compounds with different degrees of steric hindrance to planarity, as well as ester and carbazolyl derivatives. The results are discussed on the basis of the twisted intramolecular charge transfer (TICT) model, the most widely accepted model. They show that (i) the dipole moment of the A (TICT) state (long-wavelength band) shows only little solvent sensitivity (polarizability), (ii) this observed small dependence of the …
Delivering all in one: Antigen-nanocapsule loaded with dual adjuvant yields superadditive effects by DC-directed T cell stimulation
2018
Therapeutic vaccination is and remains a major challenge, particularly in cancer treatment. In this process, the effective activation of dendritic cells by a combination of distinctly acting adjuvants and an antigen is crucial for success. While most common vaccine formulations lack the efficiency to trigger sufficient T cell responses in a therapeutic tumor treatment, nanovaccines offer unique properties to tackle that challenge. Here, we report the stepwise development of a nanocapsule for vaccination approaches, comprising a shell consisting of antigen and loaded with a superadditive adjuvant combination. In a first initial step, we identified the combination of resiquimod (R848) and mur…
ANALISI ARCHEOMETRICHE DELLA CERAMICA A DECORAZIONE GEOMETRICA DIPINTA E A VERNICE NERA
2018
Di seguito vengono esposti i risultati derivanti dalla caratterizzazione petrografica e chimica di 20 reperti ceramici costituiti da scodelle, bacini, tazze, coppe, brocche a decorazione geometrica dipinta datati dalla fine del VII sec. alla metà del V sec. a.C. (campioni siglati da ER-1 a ER-10) e da coppe/skiphoi decorati a vernice nera (campioni siglati da ER-11 a ER-20), datati dalla fine del VI al V sec. a.C.. Tutti i campioni analizzati provengono dal contesto di fondazione delle mura arcaiche di Erice (TP). L’approccio metodologico ha previsto la caratterizzazione degli impasti ceramici in termini tessiturali (addensamento e distribuzione dimensionale degli inclusi, natura ed omogene…
Lung deposition of extrafine vs non-extrafine triple therapies in patients with COPD using Functional Respiratory Imaging (FRI)
2019
Introduction: FRI is a validated computational fluid dynamics (CFD)-based technique using aerosol delivery performance profile, patients’ high-resolution lung CT scans and patient-derived inhalation profiles to simulate aerosol lung deposition. Aims and Objectives: To evaluate lung deposition patterns of extrafine beclometasone dipropionate/formoterol fumarate/glycopyrronium [BDP/FF/G; TRIMBOW®] pressurized metered dose inhaler (pMDI) and non-extrafine fluticasone furoate/vilanterol/umeclidinium [FluF/VI/UMEC; TRELEGY® ELLIPTA®] dry powder inhaler (DPI) in patients with stable COPD and moderate to very severe airflow obstruction. Methods: Intrathoracic depositions of the inhaled corticoster…
Stronger proprioceptive BOLD-responses in the somatosensory cortices reflect worse sensorimotor function in adolescents with and without cerebral pal…
2020
Graphical abstract
Les Actes privés grecs de l'Archivo Ducal de Medinaceli (Tolède). II. La Vallée du Tuccio (Calabre XIIe-XIIIe siècles)
2011
Secondo volume di una ricerca sulla documentazione greca medievale in Italia meridionale, il libro è lo studio diplomatico, storico e linguistico di un fondo d'archivio proveniente dal monastero greco del San Salvatore di Messina e ora conservato negli archivi del duca di Medinaceli a Toledo. Nell'introduzione si tratta della storia economica sociale e linguistica della Calabria post bizantina, dal regno Normanno fino al primo periodo Aragonese. Seguono l'edizione diplomatica analisi e commento di 53 atti privati, un indice dei nomi e dei luoghi, in greco e in francese, un indice delle parole notevoli in alcuni casi sconosciute ai lessici medievali e moderni. Un cd-rom con la riproduzione d…
Pratique juridique grecque et économie dans la Calabre post-byzantine (XIIe-XIIIe s.)
2014
Fonti recentemente edite conservate nell'Archivio Ducal de Medinaceli consentono di studiare sotto l'aspetto linguistico, sociale ed economico una zona della Calabria meridionale che nel regno normanno-svevo mantenne una popolazione di lingua rito e diritto privato bizantino. Recently published sources preserved in the Archivio Ducal de Medinaceli allow to study a linguistic, social and economic aspect of an area of southern Calabria that in the Norman-Swabian kingdom maintained a population of rite and Byzantine private language. À partir des nouvelles sources, disponibles suite à la publication des actes privés grecs de l’Archivo Ducal de Medinaceli, on étudie ici la société rurale de l…
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
2015
Goodson, William H. et al.
DFT calculation of 1J(119Sn,13C) and 2J(119Sn,1H) coupling constants in di- and trimethyltin(IV) compounds
2008
We have tested several computational protocols, at the nonrelativistic DFT level of theory, for the calculation of 1J(119Sn, 13C) and 2J(119Sn, 1H) spin-spin coupling constants in di- and trimethyltin(IV) derivatives with various ligands. Quite a good agreement with experimental data has been found with several hybrid functionals and a double-zeta basis set for a set of molecules comprising tetra-, penta-, and hexa-coordinated tin(IV). Then, some of the protocols have been applied to the calculation of the 2J(119Sn, 1H) of the aquodimethyltin(IV) ion and dimethyltin(IV) complex with D-ribonic acid and to the calculation of 1J(119Sn, 13C) and 2J(119Sn, 1H) of the dimethyltin(IV)-glycylglycin…
Pressure–volume relationship by pharmacological stress cardiovascular magnetic resonance
2021
Abstract Background. The variation between rest and peak stress end-systolic pressure-volume relation (ΔESPVR) is an index of myocardial contractility, easily obtained during routine stress echocardiography and never tested during dipyridamole stress-cardiac magnetic resonance (CMR). We assessed the ΔESPVR index in patients with known/suspected coronary artery disease (CAD) who underwent dipyridamole stress-CMR.Methods. One-hundred consecutive patients (24 females, 63.76±10.17 years) were considered. ESPVR index was evaluated at rest and stress from raw measurement of systolic arterial pressure and end-systolic volume by biplane Simpson’s method. Results. The ΔESPVR index showed a good inte…