Search results for " DOM"

La protección de los derechos individuales: el Pacto internacional de derechos civiles y políticos de 16 de diciembre de 1966

2020

I. Introducción. II. Caracteres generales del Pacto internacional de derechos civiles y políticos. 1. Ámbito de aplicación. 2. Compromisos de los Estados partes. 3. Suspensión de las obligaciones. 4. Derechos protegidos. III. Órgano competente y técnicas de control. 1. El Comité de Derechos Humanos. 2. La aprobación de las Observaciones generales sobre los artículos del Pacto y de los Protocolos Facultativos. 3. Los Informes periódicos presentados por los Estados. 4. Las Comunicaciones estatales. 5. Las Comunicaciones individuales. IV. Referencia especial a la República Dominicana.

Los derechos del niño

2020

I. Introducción. II. La Convención de los Derechos del Niño de 1989. 1. Dificultades previas a su entrada en vigor. 2. Características principales del Convenio. 3. Derechos objeto de protección. III. El órgano internacional de control y las técnicas de control. 1. Informes. 2. Denuncias interestatales. 3. Denuncias individuales. IV. La participación de niños en conflictos armados. V. Referencia especial a la República Dominicana. Capítulo del libro "La República Dominicana y el Derecho Internacional de los Derechos Humanos",

Detergent Properties Influence the Stability of the Glycophorin A Transmembrane Helix Dimer in Lysophosphatidylcholine Micelles

2012

AbstractDetergents might affect membrane protein structures by promoting intramolecular interactions that are different from those found in native membrane bilayers, and fine-tuning detergent properties can be crucial for obtaining structural information of intact and functional transmembrane proteins. To systematically investigate the influence of the detergent concentration and acyl-chain length on the stability of a transmembrane protein structure, the stability of the human glycophorin A transmembrane helix dimer has been analyzed in lyso-phosphatidylcholine micelles of different acyl-chain length. While our results indicate that the transmembrane protein is destabilized in detergents w…

Le determinanti della produttività: fattori di offerta e fattori di domanda

2014

Models Versus Model Descriptions

2021

In the development of computer-based systems, modelling is often advocated in addition to programming, in that it helps in reflecting the application domain and that it makes the design and experiment activities of development more efficient. However, there is disagreement about what models are and how they can be used in software systems development. In this paper, we present the Scandinavian approach to modelling, which makes a clear distinction between models and model descriptions. This paper explains the connections between models, descriptions, systems, and executions. Combining the Scandinavian approach with the Kiel notion of model, we establish that both descriptions and executions…

Monitoring of the action of drugs in melanoma cells by dynamic laser speckle

2014

Abstract. This work presents the development of a protocol based on the dynamic laser speckle designed tomonitor the reaction of cancer cells of line MEL-RC08 to the application of the drug Colcemid in two differentconcentrations: 0.2 and 0.4 μg∕mL. The protocol was designed using the forward scattering approach with anHe-Ne laser of 632.8 nm illuminating the samples, a control, and two variations of Colcemid, being monitoredalong 8 h. The data were analyzed numerically in the time and in the frequency domain, and the results pre-sented the ability of the technique to monitor the action of the drug, particularly Colcemid (0.4 μg∕mL). © 2014Society of Photo-Optical Instrumentation Engineers …

Novel group A rotavirus G8 P[1] as primary cause of an ovine diarrheic syndrome outbreak in weaned lambs

2011

International audience; Rotavirus is a worldwide major cause of diarrhea outbreaks in neonatal ruminants. An outbreak of ovine diarrheic syndrome (ODS) in 50-75 days-old lambs (weaned lambs) is described. Fecal immunochromatography and intestinal immunohistochemistry for rotavirus group A were performed. In addition, semi-nested multiplex RT-PCR for G and P rotavirus genotyping in combination with sequencing were performed, to support the diagnosis and identify the viral strain. A novel ovine rotavirus group A G8 P[1] strain was determined as the main cause of the ODS observed, whereas other pathogens were ruled out.

Mediterraneo in diaspora. Soggetti plurali e nuove pratiche del domestico

2013

The sensor kinase DcuS of Escherichia coli: two stimulus input sites and a merged signal pathway in the DctA/DcuS sensor unit

2012

Abstract The membrane-integral sensor kinase DcuS of Escherichia coli consists of a periplasmically located sensory PASP domain, transmembrane helices TM1 and TM2, a cytoplasmic PASC domain and the kinase domain. Stimulus (C4-dicarboxylate) binding at PASP is required to stimulate phosphorylation of the kinase domain, resulting in phosphoryl transfer to the response regulator DcuR. PASC functions as a signaling device or a relay in signal transfer from TM2 to the kinase. Phosphorylated DcuR induces the expression of the target genes. Sensing by DcuS requires the presence of the C4-dicarboxylate transporter DctA during aerobic growth. DctA forms a sensor unit with DcuS, and a short C-termina…

Gaussian and non-Gaussian stochastic sensitivity analysis of discrete structural systems

2000

Abstract The derivatives of the response of a structural system with respect to the system parameters are termed sensitivities. They play an important role in assessing the effect of uncertainties in the mathematical model of the system and in predicting changes of the response due to changes of the design parameters. In this paper, a time domain approach for evaluating the sensitivity of discrete structural systems to deterministic, as well as to Gaussian or non-Gaussian stochastic input is presented. In particular, in the latter case, the stochastic input has been assumed to be a delta-correlated process and, by using Kronecker algebra extensively, cumulant sensitivities of order higher t…