Search results for " Dermatitis"
showing 10 items of 131 documents
S3 Guidelines: Epicutaneous patch testing with contact allergens and drugs – Short version, Part 2
2019
Epicutaneous patch testing is the diagnostic standard for the detection of allergic contact dermatitis. The present guidelines are aimed at residents and board-certified physicians in the fields of dermatology and allergology as well as other medical specialties involved in establishing the indication for patch testing and its execution in patients with contact dermatitis and other forms of delayed-type hypersensitivity. The target audience also includes other health care providers and insurance funds. Based on a systematic literature search and a formal consensus process (S3), the guidelines were developed by dermatologists in collaboration with pediatricians, occupational medicine physici…
S3 guidelines: Epicutaneous patch testing with contact allergens and drugs – Short version, Part 1
2019
Epicutaneous patch testing is the diagnostic standard for the detection of allergic contact dermatitis. The present guidelines are aimed at residents and board-certified physicians in the fields of dermatology and allergology as well as other medical specialties involved in establishing the indication for patch testing and its execution in patients with contact dermatitis and other forms of delayed-type hypersensitivity. The target audience also includes other health care providers and insurance funds. Based on a systematic literature search and a formal consensus process (S3), the guidelines were developed by dermatologists in collaboration with pediatricians, occupational medicine physici…
Recurrent wheezing during the first 3 years of life in a birth cohort of moderate-to-late preterm infants.
2019
Background Data addressing short- and long-term respiratory morbidity in moderate-late preterm infants are limited. We aim to determine the incidence of recurrent wheezing and associated risk and protective factors in these infants during the first 3 years of life. Methods Prospective, multicenter birth cohort study of infants born at 32+0 to 35+0 weeks' gestation and followed for 3 years to assess the incidence of physician-diagnosed recurrent wheezing. Allergen sensitization and pulmonary function were also studied. We used multivariate mixed-effects models to identify risk factors associated with recurrent wheezing. Results A total of 977 preterm infants were enrolled. Rates of recurrent…
Contact hypersensitivity to disodium hexachloroplatinate in mice.
1998
Complex platinum (Pt) compounds are known as occupational respiratory sensitizers whereas their role in skin exposure is unclear. In this study, both skin irritation and induction of contact hypersensitivity by halide Pt salts were characterized in mice. Repeated application of Na2[PtCl6] (5% in acetone) to both ears of naive BALB/c mice induced activation of the draining auricular lymph nodes. Flow cytometric analysis revealed a striking increase in the number of lymph node cells expressing proliferating cell nuclear antigen. In separate experiments, Na2[PtCl6] or acetone were applied only to the right ear of mice on 4-8 consecutive days and the animals were challenged on the left ear 6 da…
Papulo-purpuric dermatitis of childhood: a distinct PLEVA-like eruption associated to SARS-CoV-2 infection. Clinical, histopathological and immunohis…
2021
Abstract We observed ten children with a papular eruption with purpuric features during the SARS‐CoV‐2 pandemic in Northern Italy (May‐December 2020). Histological examination showed signs of SARS‐CoV‐2‐related dermatosis. Evidence of nucleocapsid viral proteins using SARS‐CoV‐2 (2019‐nCoV) nucleocapsid antibody revealed cuticular staining of the deep portion of the eccrine glands in all cases.
Assessment of prurigo of pregnancy in patients without atopic background
2020
Highlights • PP can develop in patients without atopic background. • Onset: late 2nd to early 3rd trimester; can persist until delivery. • Patient should be counseled accordingly. • These findings should be considered when classifying specific pregnancy dermatoses.
Transient suppression of atopy in early childhood is associated with high vaccination coverage.
2003
Objective. To analyze prevalences of allergic sensitization and atopic disease in relation to vaccination coverage. Methods. A German atopy risk-enhanced birth cohort of 1314 neonates who were born in 1990 in 5 German cities was studied. A total of 943 children participated in the follow-up visit at 5 years of age. Atopic symptoms and diagnoses (derived from structured interviews), total serum immunoglobulin E, and specific immunoglobulin E against 9 common allergens (CAP Radio-Allergo-Sorbent Test Fluoro-Enzyme Immunoassay) were evaluated. Children were grouped into dose percentiles according to cumulative doses of any vaccine given up to 5 years of age (<10%, 0–11 doses; 10%–50%, 1…
Effects of Natural Products on Contact Dermatitis
2005
Some medicinal plants, which are known to produce allergic reactions, are also specifically used as anti- inflammatory agents. Among the more relevant plants, we report species with cinnamaldehyde, cinnamic alcohol, geraniol, hydroxycitronellal, eugenol and isoeugenol are all potential allergens. In addition, fragrances, which are mixtures of small-molecul ar-weight compounds, may induce allergic contact dermatitis due to fragrance-spe cific CD4 + and CD8 + T lymphocytes. Plants from the Asteraceae family used in folk medicine as anti-inflamma tories can cause allergic contact dermatitis because of its content in sesquiterpene lactones, which have been reported as the anti- inflammatory pri…
Natural Products as Modulators of Apoptosis and their Role in Inflammation
2006
ABSTRACT: Modifications in apoptosis, a programmed form of cell death that participates in a wide variety of physiological processes, can contribute to many diseases, principally those associated with cell accumulation, such as inflammation. One hallmark of inflammation is the infiltration of leukocytes, which are programmed to undergo apoptosis at inflamed tissues. Resolution of inflammation thus involves the elimination of excess inflammatory cells by physiological cell death and the subsequent removal of apoptotic cells by phagocytes. Controlling this process may therefore be useful in the treatment of pathologies, which include an inflammatory component. Interestingly, while in some cas…
Chronic rhinosinusitis with nasal polyps impact in severe asthma patients: Evidences from the Severe Asthma Network Italy (SANI) registry
2020
Abstract Background The clinical and laboratory features of patients enrolled in the Severe Asthma Network in Italy (SANI) registry, a web-based observatory collecting demographic, clinical, functional and inflammatory data of patients with severe asthma were evaluated, with a special emphasis to chronic rhinosinusitis with nasal polyposis (CRSwNP). Methods For each eligible patients the following information has been collected: demographic data, clinical features, asthma control in the previous month according to the GINA (Global INitiative for Asthma) Guidelines and standardized questionnaires, concomitant regular and on demand treatments and inflammatory markers. Results 695 patients wit…