Search results for " Direct"
showing 10 items of 943 documents
Assessment of building energy modelling studies to meet the requirements of the new Energy Performance of Buildings Directive
2020
Abstract The cost optimal method (COM) as applied in the Energy Performance of Buildings Directive (EPBD) uses “non-calibrated deterministic reference buildings (RBs)”. Such RBs are defined with single envelope and equipment parameter values, for which calibration with actual building stock energy performance (EP) is not undertaken. Thus, it is not possible to visualise the effect of uncertainties or diversity in the input parameters on cost-optimal level benchmarks and to verify the choice of RBs. The paper proposes an update to the COM via use of “Probabilistic Bayesian calibrated RBs” to handle uncertainties and produce more realistic cost optimal levels to support policy makers in devis…
La responsabilità degli amministratori di srl. Dalla diligenza del mandatario alla ragionevolezza delle scelte gestionali
2011
This Book deals with the duties of directors in the Italian “società a responsabilità limitata” (s.r.l.), corresponding to a limited liability company without shares, in order to focus on the logic and limits of the directors’ liability and to combat any abusive bringing of the remedies laid down to enforce the above-mentioned duties. For such a purpose, the Book contains: an analysis of the interests involved, both in a s.r.l. “in bonis” and in a s.r.l. in crisis; a comparison with the same issues and solutions in the USA, England, Germany and Switzerland; and the idea to interpret the legal framework in the light of a concept of reasonableness which is more elaborate than that employed by…
Current Account Adjustment and Retained Earnings
2018
This paper develops a formal strategy to calculate current accounts with retained earnings (RE) on equity investment and analyzes their adjustment during the global financial crisis. RE are the part of companies' profits which are reinvested and not distributed to shareholders as dividends. International statistical standards treat RE on foreign direct investment and RE on portfolio investment differently: while the former enter the current and financial account, the latter do not. We show that this differential treatment strongly affects current accounts of several advanced economies, frequently referred to as financial centers, with large positions in equity (portfolio) investment. Our em…
¿Cui prodest?
1999
[Recommendations for end-of-life care in patients with chronic obstructive pulmonary disease].
2009
Over the last 20 years, advances in the treatment of patients with chronic obstructive pulmonary disease (COPD) have improved survival even among patients in the most advanced stages of the disease, such as those requiring domiciliary oxygen therapy.1,2 This improvement—in principle a positive development—has given rise to considerable clinical problems associated with the establishment of a therapeutic ceiling and the difficulty of determining prognosis in some of these patients. In this situation, the clinician should consider introducing palliative care, that is, care aimed at improving symptom control, communication, physical activity, and emotional support, in order to achieve the best…
Le manuel Corso di Lingua francese a base intuitiva de Romeo Lovera
2020
We analyze the three volumes of Romeo Lovera’s manual, Corso di Lingua francese a base intuitiva, which were intended for teaching French in secondary schools. The manual was first published in 1902 in Venice by Libreria editrice del Bollettino di Filologia Moderna, and there will be many reissues. Romeo Lovera is Italy's biggest supporter of methodological reform in the teaching of foreign languages ; it discloses, through the Bollettino di Filologia Moderna, new theories, scientific methods and their didactic applications. In their manuals, from the first lesson, through the direct and indirect intuition of the foreign language, the student learns to speak the French language by studying …
Direct RNA Nanopore Sequencing of SARS-CoV-2 Extracted from Critical Material from Swabs
2022
In consideration of the increasing prevalence of COVID-19 cases in several countries and the resulting demand for unbiased sequencing approaches, we performed a direct RNA sequencing (direct RNA seq.) experiment using critical oropharyngeal swab samples collected from Italian patients infected with SARS-CoV-2 from the Palermo region in Sicily. Here, we identified the sequences SARS-CoV-2 directly in RNA extracted from critical samples using the Oxford Nanopore MinION technology without prior cDNA retrotranscription. Using an appropriate bioinformatics pipeline, we could identify mutations in the nucleocapsid (N) gene, which have been reported previously in studies conducted in other countri…
Spillovers de la Inversion Extranjera Directa y sus efectos en las empresas colombianas
2018
El desarrollo de esta tesis gira entorno a investigar acerca de las contribuciones de la IED y sus impactos en las empresas colombianas, sobre todo, en aquellas que vienen teniendo una importante presencia con sus ventas en los mercados internacionales. Se trata de valorar a nivel cuantitativo y cualitativo el papel de los spillovers o de externalidades causadas por los flujos de inversión directa que recibe el país, sobre algunas de las actividades importantes que permiten impulsar la competitividad de las empresas colombianas con alta vocación exportadora y con presencia internacional. En especial, la posibilidad de tener acceso a nuevas tecnologías, el incentivo a buscar la eficiencia en…
Cell cycle studies on the mode of action of yeast K28 killer toxin.
1996
The virally encoded K28 killer toxin of Saccharomyces cerevisiae kills sensitive cells by a receptor-mediated process. DNA synthesis is rapidly inhibited, cell viability is lost more slowly and cells eventually arrest, apparently in the S phase of the cell cycle with a medium-sized bud, a single nucleus in the mother cell and a pre-replicated (1n) DNA content. Cytoplasmic microtubules appear normal, and no spindle is detectable. Arrest of a sensitive haploid yeast strain by alpha-factor at START gave complete protection for at least 4 h against a toxin concentration that killed non-arrested cells at the rate of one log each 2.5 h. Cells released from alpha-factor arrest were killed by toxin…