Search results for " Disease Outbreaks"

showing 8 items of 18 documents

Identification of Cpgp40/15 Type Ib as the Predominant Allele in Isolates of Cryptosporidium spp. from a Waterborne Outbreak of Gastroenteritis in So…

2006

ABSTRACT Cryptosporidium sp. isolates from a waterborne outbreak of diarrhea in France were analyzed by PCR-restriction fragment length polymorphism analysis and sequencing of the Cpgp40/15 locus. Ninety-one percent of the isolates were Cryptosporidium hominis type Ib. The results of this study and those of studies of other outbreaks suggest that the type Ib allele is the predominant allele associated with waterborne cryptosporidiosis.

MESH : France/epidemiologyEpidemiologyMESH : polymerase chain reactionMESH : molecular sequence dataProtozoan ProteinsCryptosporidiosisPolymerase Chain Reactionlaw.inventionDisease OutbreaksMESH : Cryptosporidium/geneticsMESH : water/parasitologylaw[ SDV.MP ] Life Sciences [q-bio]/Microbiology and ParasitologyMESH : gastroenteritis/parasitologyMESH : Polymorphism restriction fragment lengthwaterborne outbreakPolymerase chain reactionbiologyMESH : DNA Protozoan/analysisCryptosporidiumGastroenteritisDiarrheaMESH : Cryptosporidiosis/epidemiologyFrancemedicine.symptomMESH : Cryptosporidium/classificationCryptosporidium hominisMESH : Protozoan proteins/metabolismPolymorphism Restriction Fragment LengthMicrobiology (medical)MESH : Cryptosporidium/isolation&purificationMolecular Sequence DataCryptosporidiumLocus (genetics)MESH : Disease outbreaksMicrobiologyMESH : Cryptosporidiosis/parasitologymedicineAnimalsAlleleGenotyping[SDV.MP] Life Sciences [q-bio]/Microbiology and ParasitologyAllelesMESH : animalsMESH : sequence analysis DNAOutbreakWaterSequence Analysis DNADNA Protozoanbiology.organism_classificationMESH : protozoan proteins/geneticsVirologygenotypingMESH : Gastroenteritis/epidemiologyMESH : Alleles
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Multicentre Italian study of SARS-CoV-2 infection in children and adolescents, preliminary data as at 10 April 2020

2020

Data on features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents are scarce. We report preliminary results of an Italian multicentre study comprising 168 laboratory-confirmed paediatric cases (median: 2.3 years, range: 1 day–17.7 years, 55.9% males), of which 67.9% were hospitalised and 19.6% had comorbidities. Fever was the most common symptom, gastrointestinal manifestations were frequent; two children required intensive care, five had seizures, 49 received experimental treatments and all recovered.

MalePediatricsEpidemiologyProtease InhibitorComorbiditymedicine.disease_causeClinical Laboratory TechniqueSevere Acute Respiratory SyndromeDisease OutbreaksFeces0302 clinical medicineSettore MED/38 - Pediatria Generale E SpecialisticaCOVID-19 TestingRetrospective StudiePandemic030212 general & internal medicineViralChildCoronavirusPediatricDisease OutbreakCoinfectionHospitals PediatricSettore MED/38HospitalsDiarrheaTreatment OutcomeSARS-CoV-2 infection; children; covid-19; hydroxychloroquine; pneumonia; Adolescent; Antiviral Agents; Betacoronavirus; COVID-19; COVID-19 Testing; Child; Child Preschool; Chronic Disease; Clinical Laboratory Techniques; Coinfection; Comorbidity; Coronavirus; Coronavirus Infections; Diarrhea; Disease Outbreaks; Feces; Female; Fever; Hospitals Pediatric; Humans; Immunocompromised Host; Infant; Infant Newborn; Italy; Male; Noninvasive Ventilation; Pandemics; Pneumonia Viral; Protease Inhibitors; Retrospective Studies; SARS-CoV-2; Severe Acute Respiratory Syndrome; Treatment OutcomeItalyChild PreschoolCoinfectionFemalemedicine.symptomCoronavirus InfectionsRapid CommunicationHumanDiarrheamedicine.medical_specialtyCOVID-19; ItalyhydroxychloroquineAdolescentFeverCoronaviruPneumonia ViralAntiviral Agents03 medical and health sciencesBetacoronavirusImmunocompromised Hostchildren030225 pediatricsVirologyIntensive caremedicineHumanspneumoniaProtease InhibitorsPreschoolPandemicsRetrospective StudiesAntiviral Agentchildren; covid-19; hydroxychloroquine; pneumonia; SARS-CoV-2 infection; Adolescent; Antiviral Agents; Betacoronavirus; Child; Child Preschool; Chronic Disease; Clinical Laboratory Techniques; Coinfection; Comorbidity; Coronavirus; Coronavirus Infections; Diarrhea; Disease Outbreaks; Feces; Female; Fever; Hospitals Pediatric; Humans; Immunocompromised Host; Infant; Infant Newborn; Italy; Male; Noninvasive Ventilation; Pandemics; Pneumonia Viral; Protease Inhibitors; Retrospective Studies; Severe Acute Respiratory Syndrome; Treatment OutcomeNoninvasive VentilationBetacoronaviruPandemicbusiness.industryClinical Laboratory TechniquesCoronavirus InfectionSARS-CoV-2pneumonia.SARS-CoV-2 infectionPublic Health Environmental and Occupational HealthInfant NewbornCOVID-19InfantRetrospective cohort studymedicine.diseaseNewbornComorbidityCoronavirusPneumoniaChronic DiseaseFecebusiness
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Phylogenetic analysis in the clinical risk management of an outbreak of hepatitis C virus infection among transfused thalassaemia patients in Italy

2021

Background: Occurrence of hepatitis C virus (HCV) infection is reduced by effective risk management procedures, but patient-to-patient transmission continues to be reported in healthcare settings. Aim: To report the use of phylogenetic analysis in the clinical risk management of an HCV outbreak among 128 thalassaemia outpatients followed at a thalassaemia centre of an Italian hospital. Methods: Epidemiological investigation and root-cause analysis were performed. All patients with acute hepatitis and known chronic infection were tested for HCV RNA, HCV genotyping, and NS3, NS5A, and NS5B HCV genomic region sequencing. To identify transmission clusters, phylogenetic trees were built for each…

SofosbuvirClinical risk management Hepatitis C virus (HCV) Molecular epidemiology Nosocomial outbreak Phylogenetic analysis Antiviral Agents Bayes Theorem Disease Outbreaks Genotype Hepacivirus Humans Italy Phylogeny Risk Management Hepatitis C ThalassemiaHepacivirusHepacivirus030501 epidemiologySettore MED/42 - Igiene Generale E Applicatamedicine.disease_causeDisease OutbreaksSettore MED/07chemistry.chemical_compoundSettore BIO/13 - Biologia ApplicataEpidemiologyMedicinePhylogenySettore MED/12 - Gastroenterologia0303 health sciencesClinical risk managementPhylogenetic analysisbiologyTransmission (medicine)virus diseasesGeneral MedicineHepatitis CHepatitis C virus (HCV)Hepatitis CInfectious DiseasesItalyMolecular epidemiologyThalassemia0305 other medical sciencemedicine.drugMicrobiology (medical)Ledipasvirmedicine.medical_specialtyGenotypeHepatitis C virusAntiviral Agents03 medical and health sciencesPhylogenetic analysiInternal medicineHumansRisk Management030306 microbiologybusiness.industryNosocomial outbreakBayes Theorembiology.organism_classificationmedicine.diseasedigestive system diseasesChronic infectionchemistrybusiness
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Analysis of integrated virological and epidemiological reports of norovirus outbreaks collected within the Foodborne Viruses in Europe network from 1…

2008

ABSTRACT The Foodborne Viruses in Europe network has developed integrated epidemiological and virological outbreak reporting with aggregation and sharing of data through a joint database. We analyzed data from reported outbreaks of norovirus (NoV)-caused gastroenteritis from 13 European countries (July 2001 to July 2006) for trends in time and indications of different epidemiology of genotypes and variants. Of the 13 countries participating in this surveillance network, 11 were capable of collecting integrated epidemiological and virological surveillance data and 10 countries reported outbreaks throughout the entire period. Large differences in the numbers and rates of reported outbreaks pe…

Veterinary medicineEpidemiologyMESH : Genotypemedicine.disease_causeDisease OutbreaksFoodborne DiseasesMESH: GenotypeEpidemiologyMedicineMESH: Disease OutbreaksMESH: Caliciviridae InfectionsCaliciviridae Infections0303 health sciencesFood poisoningbiologyTransmission (medicine)Incidence (epidemiology)Gastroenteritis3. Good healthEuropeMESH : GastroenteritisDisease Notification[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/VirologyMESH : Caliciviridae InfectionsMicrobiology (medical)MESH: Norovirusmedicine.medical_specialtyGenotypeMESH: Disease NotificationMESH : Europe[ SDV.MP.VIR ] Life Sciences [q-bio]/Microbiology and Parasitology/VirologyMESH: Multivariate Analysis03 medical and health sciencesEnvironmental healthHumansMESH : Disease OutbreaksMESH : Foodborne DiseasesMESH: Foodborne DiseasesDisease Notification030304 developmental biologyMESH: Humans030306 microbiologybusiness.industryMESH : NorovirusNorovirusMESH : HumansOutbreakMESH : Multivariate AnalysisMESH : Disease Notificationmedicine.diseasebiology.organism_classificationCaliciviridaeMESH: GastroenteritisMultivariate AnalysisNorovirusMESH: Europebusiness
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Distinct Clones of Yersinia pestis Caused the Black Death

2010

From AD 1347 to AD 1353, the Black Death killed tens of millions of people in Europe, leaving misery and devastation in its wake, with successive epidemics ravaging the continent until the 18th century. The etiology of this disease has remained highly controversial, ranging from claims based on genetics and the historical descriptions of symptoms that it was caused by Yersinia pestis to conclusions that it must have been caused by other pathogens. It has also been disputed whether plague had the same etiology in northern and southern Europe. Here we identified DNA and protein signatures specific for Y. pestis in human skeletons from mass graves in northern, central and southern Europe that …

Yersinia pestis[SDV]Life Sciences [q-bio]Sequence HomologyDiseaseMESH: Base SequenceMESH: Genetic Markers[SHS]Humanities and Social SciencesDisease OutbreaksInfectious Diseases/Bacterial InfectionsMESH: GenotypeGenotypeMass ScreeningBiology (General)MESH: Disease OutbreaksMESH: PhylogenyCladePhylogenyGenetics0303 health sciencesMicrobiology/Microbial Evolution and GenomicsbiologyClones; Yersinia pestis; Black DeathBacterialGenetics and Genomics/Microbial Evolution and Genomics3. Good healthEuropeEvolutionary Biology/Human EvolutionInfectious DiseasesResearch ArticleDNA BacterialGenetic MarkersGenotypeQH301-705.5Molecular Sequence DataImmunologyMESH: Yersinia pestisZoologyMolecular Biology/Molecular EvolutionPlague (disease)MESH: PlagueMESH: Sequence Homology Nucleic AcidMicrobiologyNO03 medical and health sciencesPhylogeneticsSequence Homology Nucleic AcidVirologyGeneticsHumansMESH: Mass ScreeningEpidemicsMolecular BiologyMESH: EpidemicsMass screening030304 developmental biologyPlagueEvolutionary BiologyMESH: HumansMESH: Molecular Sequence DataNucleic AcidBase Sequence030306 microbiologyGenetics and GenomicsDNARC581-607biology.organism_classificationMESH: DNA BacterialYersinia pestisBase Sequence; DNA Bacterial; Disease Outbreaks; Epidemics; Europe; Genetic Markers; Genotype; Humans; Mass Screening; Molecular Sequence Data; Phylogeny; Plague; Sequence Homology Nucleic Acid; Yersinia pestisEtiologyParasitologyMESH: EuropeImmunologic diseases. Allergy
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Import of norovirus infections in the Netherlands and Ireland following pilgrimages to Lourdes, 2008--preliminary report.

2008

International audience; Between mid-September and 19 October 2008, nine clusters of norovirus infection involving around 90 primary cases and over a hundred secondary cases were identified in patients from the Netherlands, Ireland, Italy and France, linked to pilgrimage to Lourdes, France.

[SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/VirologyMESH : NetherlandsMESH : NorovirusMESH : HumansMESH : Risk Factors[ SDV.MP.VIR ] Life Sciences [q-bio]/Microbiology and Parasitology/VirologyMESH : IncidenceMESH : GastroenteritisMESH : TravelMESH : Population SurveillanceMESH : Creutzfeldt-Jakob SyndromeMESH : Disease OutbreaksMESH : Caliciviridae InfectionsMESH : Risk AssessmentMESH : FranceMESH : Ireland
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Face mask use in the Community for Reducing the Spread of COVID-19: a systematic review

2021

ABSTRACTBackgroundEvidence is needed on the effectiveness of wearing face masks in the community to prevent SARS-CoV-2 transmission.MethodsSystematic review and meta-analysis to investigate the efficacy and effectiveness of face mask use in a community setting and to predict the effectiveness of wearing a mask. We searched MEDLINE, EMBASE, SCISEARCH, The Cochrane Library and pre-prints from inception to 22 April 2020 without restriction by language. We rated the certainty of evidence according to Cochrane and GRADE approach.FindingsOur search identified 35 studies, including 3 randomised controlled trials (RCTs) (4017 patients), 10 comparative studies (18984 patients), 13 predictive models,…

disease outbreak0301 basic medicinemedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)face maskSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PopulationMEDLINEpandemicsCochrane LibraryCOVID−19law.invention03 medical and health sciences0302 clinical medicinenursingsystematic reviewRandomized controlled triallawprevention and control [MeSH]Health careMedicine030212 general & internal medicineIntensive care medicineeducationlcsh:R5-920education.field_of_studySARS—CoV−2business.industrypandemicGeneral MedicineSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheSurgical mask030104 developmental biologySystematic reviewdisease outbreaksPhysical therapyMedicinecommunityObservational studycommunity; COVID−19; disease outbreaks; face mask; pandemics; prevention and control [MeSH]; SARS—CoV−2; systematic reviewlcsh:Medicine (General)business
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Reduced Admissions for Cerebrovascular Events during COVID-19 Outbreak in Italy

2020

Supplemental Digital Content is available in the text.

disease outbreakMalemedicine.medical_treatment030204 cardiovascular system & hematologyItaly; cerebral hemorrhage; disease outbreaks; incidence; ischemic attack transient0302 clinical medicineEpidemiology80 and overMedicineischemic attack transientThrombolytic Therapy10178Acute ischemic stroke10177ThrombectomyAged 80 and overIschemic AttackTransientIncidence (epidemiology)Endovascular ProceduresMiddle AgedHospitalization1006210183ItalyComputingMethodologies_DOCUMENTANDTEXTPROCESSINGSettore MED/26 - NeurologiaFemaleCardiology and Cardiovascular Medicinecerebral hemorrhage; disease outbreaks; incidence; ischemic attack transient; Italy; Aged; Aged 80 and over; COVID-19; Cerebral Hemorrhage; Endovascular Procedures; Female; Hospitalization; Humans; Ischemic Attack Transient; Ischemic Stroke; Italy; Male; Middle Aged; Thrombectomy; Thrombolytic Therapymedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)RevascularizationSettore MED/261015203 medical and health sciencesHumansAgedIschemic StrokeAdvanced and Specialized Nursingcerebral hemorrhagebusiness.industryOutbreakCOVID-19Emergency medicinedisease outbreaksincidenceBrief ReportsNeurology (clinical)business030217 neurology & neurosurgery
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