Search results for " Editor"

Quelques aspects de la contradiction et de la remise en cause dans le genre Letters to the editor

2001

Cette communication se fixe comme objectif de repérer quelques stratégies discursives de deux communautés de chercheurs et de comparer leur matérialisation linguistique dans un corpus de Letters to the Editor composé à partir de deux revues : The American Journal of Clinical Nutrition et de The Lancet. La stratégie de remise en cause est analysée comme le mode explicite ou implicite de la contradiction apportée à un fait scientifique établi. Ce discours, identifié comme un genre, se situe dans la logique de véridiction du discours scientifique. The aim of this study is to pick out a few discursive strategies in two research communities and to perform a comparative analysis of their linguist…

Les éditorialistes : auteurs scientifiques ou acteurs sociaux

2007

Les éditoriaux peuvent être perçus comme une interface entre la recherche scientifique et l'opinion publique. Nous avons cherché à savoir si l'objectif des éditorialistes scientifiques n'est que de poursuivre une tradition journalistique, ou de mettre en œuvre des stratégies idéologiques ou sociétales, justifiant ainsi leur raison d'être dans la société au sens large. Cette étude présente les thèmes sélectionnés dans deux revues médicales britanniques de grande réputation sur une période de deux ans, ainsi que les liens potentiels avec les articles de recherche publiés dans les mêmes journaux scientifiques. Le but et l'utilisation même des éditoriaux sont analysés tant à l'intérieur qu'à l'…

Dyslexia—Early Identification and Prevention: Highlights from the Jyväskylä Longitudinal Study of Dyslexia

2015

Over two decades of Finnish research, monitoring children born with risk for dyslexia has been carried out in the Jyvaskyla Longitudinal Study of Dyslexia (JLD). Two hundred children, half at risk, have been assessed from birth to puberty on hundreds of measures. The aims were to identify measures of prediction of later reading difficulty and to instigate appropriate and earliest diagnosis and intervention. We can identify at-risk children from newborn electroencephalographic brain recordings (Guttorm et al., J Neural Transm 110:1059–1074, 2003). Predictors are also apparent from late-talking infants who have familial background of dyslexia (Lyytinen and Lyytinen, Appl Psycolinguistics 25:3…

Reply to the letter to the editor ‘How much evidence isn't in evidence-based guidelines?’ by Johnson et al.

2015

ABSTRACT ESMO produces pan-European, multidisciplinary, peer-reviewed and updatable guidelines with global impact on current clinical practice, with the intention of providing the practising health professional in cancer care with an easy to use, evidence-based tool for optimal patient management. Levels of evidence and strength of recommendation metrics are provided. In the Dyspnoea ESMO CPG, we strove to fulfill these targets, though we accept any productive criticism that will contribute to the improvement of the product.

La idea del poder prevalece en los medios de comunicación

2008

Pyridoxine dependent epilepsies: new therapeutical point of view

2017

Abstract Pyridoxine dependent epilepsies (PDEs) are rare autosomal recessive disorders with onset in neonatal period. Seizures are typically not responsive to conventional antiepileptic drugs, but they cease after parental pyridoxine administration. Atypical forms are characterized partly response to pyridoxine and a late onset of symptoms (up to the age of three years). Prevalence is variable and it has rarely been described. The genes involved in PDEs are the gene encoding for the Alpha-aminoadipic-semialdehyde dehydrogenase (ALDH7A1) and PROSC gene, which encodes a pyridoxal-5-phosphate binding protein. Mutations in the gene encoding for the pyridoxal-5′-phosphate oxidase enzyme (PNPO) a…

''Limits in endurance performance of octogenarian athletes''

2013

TO THE EDITOR: A recent study of Trappe et al. (3) showed that the aerobic power of octogenarian lifelong endurance athletes was approximately double that of untrained octogenarians (38 vs. 21 ml·kg 1 ·min 1 ). These remarkable aerobic capacities are the highest ever recorded in this age group. However, the impact of the identified physiological capacities on actual endurance performances has not been addressed, as no running performance indicators of the octogenarian athletes were provided in this study. We hereby suggest that, although trained octogenarian athletes can achieve levels of aerobic fitness well above their untrained counterpart, as a group they actually have not yet reached t…

Clinical and demographic characteristics of patients dying from COVID-19 in Italy vs China.

2020

Abstract Coronavirus disease 2019 (COVID‐19), an infectious outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2),1 has now progressed to global pandemic.2 Besides the compelling need to understand the novel biological pathways underlying the virulence and pathogenicity of SARS‐CoV‐2 in humans to enable the development of appropriate interventions and therapies,3,4 the noticeable difference in mortality rates between Asian and European populations is one of the most significant issues demanding the attention of biologists, epidemiologists and clinicians around the world. This article is protected by copyright. All rights reserved.

Early effects of unfractionated heparin on clinical and radiological signs and D-dimer levels in patients with COVID-19 associated pulmonary embolism…

2021

Immunophenotype and molecular characterisation of adenocarcinoma of the small intestine

2009

Background: Despite having a dramatically larger surface area than the large intestine, the small intestine is an infrequent site for the development of adenocarcinoma. To better understand the molecular abnormalities in small bowel adenocarcinoma (SBA), we characterised a number of candidate oncogenic pathways and the immunophenotype of this rare cancer. Methods: Tissue microarrays were constructed from tumour samples from 54 patients with all stages of the disease. Immunohistochemistry and microsatellite instability (MSI) testing were conducted. Results: The profile of cytokeratin 20 and 7 coexpression was variable, but expression of caudal type homeobox transcription factor 2 (CDX2) was …