Search results for " Flow velocity"

The effects of linearly increasing flip angles on 3D inflow MR angiography

1994

As recently demonstrated, spin saturation effects in 3D time-of-flight (TOF) MR angiography (MRA) can be reduced by using RF pulses with linearly increasing flip angles (ramp pulses) in the main direction of flow. We developed a model for calculating the signal distribution of proton flow within the excitation volume (slab) for different ramp slopes and compared the results with the measured distribution for the lower-leg arteries. The ramp pulses were generated using the Fourier transformation of the desired excitation profiles. With a bandwidth of 6 kHz and a pulse length of 2.56 ms satisfactory ramps with variable slopes were generated and applied in a standard flow-compensated 3D FISP s…

Regional blood flow in deep structures of the brain measured in acute cat experiments by means of a new beta-sensitive semiconductor needle detector.

1967

Regional cerebral blood flow was measured by means of isotope clearance with a new type of solid state beta-sensitive needle detector (diameter 0.9 mm) introduced into the brain tissue in acute cat experiments. The flow values obtained within the cortex were compared with values recorded above the same cortical region with the same needle detector, or with a small GM-tube. The insertion of the needle detector into the brain tissue gave rise to injury (checked histologically) which deformed the clearance curves in a manner suggesting that the normal circulation had been destroyed within the tissue from which the measurements were made.

Investigation of the hemodynamic flow conditions and blood-induced stresses inside an abdominal aortic aneurysm by means of a SPH numerical model.

2019

The estimation of blood flow-induced loads occurring on the artery wall is affected by uncertainties hidden in the complex interaction of the pulsatile flow, the mechanical parameters of the artery, and the external support conditions. To circumvent these difficulties, a specific tool is developed by combining the aorta displacements measured by an electrocardiogram-gated-computed tomography angiography, with the blood velocity field computed by a smoothed particle hydrodynamics (SPH) numerical model. In the present work, the SPH model has been specifically adapted to the solution of the 3D Navier-Stokes equations inside a domain with boundaries of prescribed motion. Images of the abdominal…

Experimental investigation on the “horizontal” turbulence and the bed deformation: preliminary results

2005

Oxygen diffusion in tissues supplied by capillaries.

1968

(1968). Oxygen Diffusion in Tissues Supplied by Capillaries. Scandinavian Journal of Clinical and Laboratory Investigation: Vol. 21, No. sup102, pp. II-B-II-B.

Automated Measurement of Microcirculatory Blood Flow Velocity in Pulmonary Metastases of Rats

2014

Because the lung is a major target organ of metastatic disease, animal models to study the physiology of pulmonary metastases are of great importance. However, very few methods exist to date to investigate lung metastases in a dynamic fashion at the microcirculatory level, due to the difficulty to access the lung with a microscope. Here, an intravital microscopy method is presented to functionally image and quantify the microcirculation of superficial pulmonary metastases in rats, using a closed-chest pulmonary window and automated analysis of blood flow velocity and direction. The utility of this method is demonstrated to measure increases in blood flow velocity in response to pharmacologi…

In vivo investigations on microcirculatory disturbances induced by crenated erythrocytes following norepinephrine application

1974

Using a special apparatus for high resolution cinephotomicrography, which allows simultaneous observation and recording of microcirculatory changes, alterations in blood flow patterns and in red cell shape during norepinephrine acting have been studied. Under physiological conditions, and during slowing of capillary blood flow due to gradual removing of 20–25% of the circulating blood volume, the normal red cells are extremely deformable while passing through mesenteric capillaries. After application of norepinephrine a general arteriolar constrictive response in the bowel wall occurs, causing a further slowing of the capillary blood flow in the mesentery. Under these circumstances the eryt…

Entropic approach to estimate the mean flow velocity: experimental investigation in laboratory flumes

2015

The paper deals with the linear entropic relationship between the maximum velocity, u max , and the mean flow velocity, u m , through a dimensionless parameter Φ(M), in open-channel flow. The analysis is conducted with the aid of experimental data collected in straight laboratory flumes under different bed and side-walls roughness conditions. In particular, rough/vegetated beds and smooth/rough side-walls conditions have been investigated. The results show that, in the investigated conditions (with exception of low-submergence vegetated bed—h/k v  < 2), Φ(M) can be assumed equal to a value that is very close to that found in natural channels. This demonstrates that Φ(M) is able to implicitl…

Hemodilution in isolated tumor perfusion.

1984

Experiments are performed to study the influence of local hemodilution on tumor blood flow, oxygen availability in tumor tissue and O2 consumption of cancer cells. The results obtained clearly show that hemodilution in isolated tumor perfusion can distinctly improve nutritive blood flow through solid tumors. This can be utilized to enhance pharmacokinetics of antitumor drugs. Due to the improved metabolic status, the pharmacodynamics of some antitumor drugs should also be enhanced. To achieve a maximum improvement of the O2 supply to the tumor, hematocrit values should not be decreased below 0.20.

Hyper-concentrated flow and surface velocity estimation by digital imaging technique: a study case

2015

This paper investigates the utility of digital imaging technique for performing surface velocity measurements of hyper-concentrated flows. The analysis is conducted with the aid of data collected in a scale laboratory flume constructed at the Hydraulic laboratory of the Department of Civil, Environmental, Aerospatial and of Materials Engineering (DICAM) – University of Palermo (Italy). In particular the present paper describes the setup of a laboratory test and the applicability of a fully digital imaging approach.