Search results for " Forensic"

showing 10 items of 1486 documents

A new resonant Laser-SNMS system for environmental ultra-trace analysis: Installation and optimization

2017

Abstract Localization, analysis and mobility of radioactive contaminated particles is of major concern for assessment of contamination threads and nuclear forensics. For this purpose, a new resonant Laser-SNMS system was developed and set up at the Institute for Radioecology and Radiation Protection for spatially resolved ultra-trace analysis of low concentrated radionuclides directly on environmental samples. This paper describes the adaption and combination of a dedicated Ti:sapphire laser system with a commercial TOF-SIMS instrument for resonant Laser-SNMS. The project includes computer simulations for optimization of the TOF analyzer. Results on synthetic uranium and technetium samples …

medicine.medical_specialtySpectrum analyzerNuclear forensicsNuclear engineeringchemistry.chemical_elementNanotechnology01 natural scienceslaw.inventionRadioecologylaw0103 physical sciencesmedicinePhysical and Theoretical Chemistry010306 general physicsInstrumentationSpectroscopyRadionuclideChemistrybusiness.industry010401 analytical chemistryUraniumContaminationCondensed Matter PhysicsLaser0104 chemical sciencesRadiation protectionbusinessInternational Journal of Mass Spectrometry
researchProduct

Telemedicine during Covid-19 pandemic: Advantage or critical issue?

2020

Telemedicine offers a support to traditional medicine, delivering clinical services when distance is a critical factor. Although this tool does not replace a medical examination, during Covid-19 pandemic, it reduces the spread of infection and avoids the need for a patient’s visit. It is useful in the management of chronic disorders or for patients undergoing palliative treatment. The University Hospital of Palermo has applied this in cases of chronic illness caring for patients who cannot stop their treatment, such as Department of Onco-Haematology, Internal Medicine, Dermatology, etc. The Department of Legal Medicine of Palermo, in particular, is also using telemedicine to manage medico-…

medicine.medical_specialtyTelemedicinePalliative careCoronavirus disease 2019 (COVID-19)Pneumonia ViralHealth Services AccessibilityPublic health serviceBetacoronavirus03 medical and health sciences0302 clinical medicineSettore MED/43 - Medicina LegalePandemicHumansMedicine030216 legal & forensic medicine030212 general & internal medicineDisease management (health)PandemicsSARS-CoV-2business.industryCommunicationPalliative CareMedical jurisprudenceCOVID-19Disease ManagementGeneral Medicinemedicine.diseaseTelemedicineTelemedicine covid 19 clinical servicesOutpatient visitsItalyChronic DiseaseMedical emergencyCoronavirus InfectionsbusinessMedico-Legal Journal
researchProduct

Short- and long-term effects of vinblastine on the rat adrenal medulla

1979

The effects of a single high dose (10mg/kg) of vinblastine (vb) sulfate (“Velbe”, Lilly) on the ultrastructure, catecholamine (CA) content and activity of CA-synthesizing enzymes of the rat adrenal medulla were studied for up to 120h after intravenous injection of the drug.

medicine.medical_specialtyTime FactorsHistologyChemical PhenomenaVinblastinePathology and Forensic MedicineInternal medicineSingle high doseEnterochromaffin CellsmedicineAnimalsCells Culturedchemistry.chemical_classificationCell BiologyMolecular medicineRatsVinblastineChemistryEnzymemedicine.anatomical_structureEndocrinologychemistryAdrenal MedullaUltrastructureCatecholamineFemaleAdrenal medullamedicine.drugCell and Tissue Research
researchProduct

p53 Involvement in the control of murine hair follicle regression.

2001

p53 is a transcription factor mediating a variety of biological responses including apoptotic cell death. p53 was recently shown to control apoptosis in the hair follicle induced by ionizing radiation and chemotherapy, but its role in the apoptosis-driven physiological hair follicle regression (catagen) remains to be elucidated. Here, we show that p53 protein is strongly expressed and co-localized with apoptotic markers in the regressing hair follicle compartments during catagen. In contrast to wild-type mice, p53 knockout mice show significant retardation of catagen accompanied by significant decrease in the number of apoptotic cells in the hair matrix. Furthermore, p53 null hair follicles…

medicine.medical_specialtyTumor suppressor genemedicine.medical_treatmentDown-RegulationApoptosisBiologyPathology and Forensic MedicineTelogen effluviumMiceBcl-2-associated X proteinDownregulation and upregulationInternal medicineProto-Oncogene ProteinsmedicineAnimalsbcl-2-Associated X ProteinMice Knockoutintegumentary systemGrowth factorAlopecia areatamedicine.diseaseHair follicleCell biologyUp-RegulationMice Inbred C57BLEndocrinologymedicine.anatomical_structureInsulin-Like Growth Factor Binding Protein 3Proto-Oncogene Proteins c-bcl-2Knockout mousebiology.proteinCommentaryFemaleTumor Suppressor Protein p53Hair FollicleThe American journal of pathology
researchProduct

The physiological impact of proinsulin C-peptide

1999

Abstract The proinsulin C-peptide fulfills an important function in the biosynthesis of insulin by facilitating the formation of the correct secondary and tertiary structure of the hormone. C-peptide and insulin are released in equimolar amounts to the circulation but C-peptide has generally been considered to be biologically inert. However, recent studies indicate that C-peptide administration to type 1 diabetes patients is accompanied by improved renal function, amelioration of autonomic dysfunction, stimulated tissue glucose utilization and augmented skin and muscle blood flow. The cellular mechanisms underlying these effects may be related to C-peptide's capacity to stimulate both Na + …

medicine.medical_specialtyType 1 diabetesbiologyC-peptideInsulinmedicine.medical_treatmentATPasebiology.organism_classificationmedicine.diseasePathology and Forensic Medicinechemistry.chemical_compoundEndocrinologychemistryEnosPhysiology (medical)Internal medicinemedicinebiology.proteinNa+/K+-ATPaseHormoneProinsulinPathophysiology
researchProduct

The effect of L-thyroxine on the metamorphosis of Ascidia malaca

1981

Larvae of Ascidia malaca, both before and after hatching, were treated with L-thyroxine solutions. The effect of the thyroid hormone was to induce the onset of metamorphosis and then to cause the rate at which body reorganization occurred to increase. In treated larvae the resorption of the tail occurred only few hours after hatching, and a beating heart appeared form 10 to 15 h earlier than in the control larvae. These results are discussed in the context of a probable relationship between the occurrence of a hormonal metamorphic factor and the button cells of the trunk.

medicine.medical_specialtyanimal structuresHistologygenetic structuresmedia_common.quotation_subjectContext (language use)Pathology and Forensic MedicineInternal medicinemedicineAnimalsUrochordataMetamorphosismedia_commonLarvabiologyHatchingfungiThyroidMetamorphosis BiologicalCell Biologybiology.organism_classificationResorptionAscidiaThyroxineEndocrinologymedicine.anatomical_structureLarvaHormoneCell and Tissue Research
researchProduct

Death caused by a chain saw – homicide, suicide or accident?

1999

A 31-year-old farm worker was found dead beside a chain saw. Based on the testimony of a colleague and because of the situation at the site, the police very soon presupposed an accident. It was assumed that the victim had slipped on the sodden ground and had been killed by the subsequent swerving of the saw when starting the engine. The body presented with a deep lacerated wound at the right side of the nape of the neck, including the first cervical vertebra, the medullary canal and the right mandible as well as multiple fissures of the occipital bone, which were attributed to repeated forceful use of the chain by another person. A second wound with relatively sharp edges and a tangential f…

medicine.medical_specialtybusiness.industryGeneral surgeryOccipital boneMandiblePoison controlSuicide preventionPathology and Forensic MedicineSurgeryAccident (fallacy)Skullmedicine.anatomical_structureHomicidemedicineHomicide suicidebusinessLawForensic Science International
researchProduct

Endokarditische Restzust�nde und Klappenfehler

1954

medicine.medical_specialtybusiness.industryInternal medicineValvular defectsmedicineCardiologyCell BiologyGeneral MedicineResidualbusinessMolecular BiologyPathology and Forensic MedicineVirchows Archiv f�r Pathologische Anatomie und Physiologie und f�r Klinische Medizin
researchProduct

The role of the microcirculation in multiple organ dysfunction syndrome (MODS): a review and perspective

1996

Major advances in intensive care medicine during the past two decades have altered the spectrum of disease encountered by intensive care physicians, anaesthesiologists, traumatologists and pathologists. One of the most important manifestations of severe trauma or infections is the multiple organ dysfunction syndrome (MODS), a life-threatening condition that often ends in multiple organ failure (MOF) and death. Evidence gathered from clinical and morphological observations in humans, taken together with experimental animal studies and a vast accumulation of in vitro data, clearly indicate that the microcirculation lies at the centre of this complex process, which results in peripheral vascul…

medicine.medical_specialtybusiness.industryMicrocirculationMultiple Organ FailureOrgan dysfunctionCell BiologyGeneral MedicineDiseasemedicine.diseasePathology and Forensic MedicineMicrocirculationSepsisExperimental animalSevere traumaIntensive careAnimalsHumansMedicinemedicine.symptombusinessMultiple organ dysfunction syndromeIntensive care medicineMolecular BiologyVirchows Archiv
researchProduct

Is It a Metastatic Disease: A Case Report and New Understanding of Rosai-Dorfman Disease?

2017

medicine.medical_specialtybusiness.industryNeoplasms Second PrimaryDermatologyGeneral MedicineDiseasemedicine.diseaseDermatologyPathology and Forensic MedicineDiagnosis Differential030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesisNeoplasmsMedicineHumansHistiocytosis SinusbusinessRosai–Dorfman diseaseThe American Journal of dermatopathology
researchProduct