Search results for " Form"
showing 10 items of 4997 documents
685 Food Allergy - Gastro-Esophageal Reflux Disease Association in Infants
2012
Background Cow’s milk allergy is considered to be the first and most common type of allergy during early infancy. Gastro-esophageal reflux disease and cow’s milk allergy are two different diseases with common clinical features. The aim of the study was to evaluate the clinical data in relation with gastroesophageal reflux and cow’s milk allergy in infants. Material and Methods The prospective study includes 36 infants aged between 2–6 months who attended at Pediatric Clinic during the year 2011 for the clinical evocative manifestations of gastroesophageal reflux. Study protocol includes: clinical criteria, familial/personal atopic features, mother diet, duration of breastfeeding, infant for…
Recensione a Romano Alquati, Sulla riproduzione della capacità attiva vivente. L’industrializzazione della soggettività, Roma, DeriveApprodi, 2021, p…
2022
Recensione a Romano Alquati, Sulla riproduzione della capacità attiva vivente. L’industrializzazione della soggettività, Roma, DeriveApprodi, 2021, pp. 218
Electromechanical Numerical Analysis of an Air-Core Pulsed Alternator via Equivalent Network Formulation
2017
In this paper, the numerical analysis on an air-core pulsed alternator is presented. Since compulsators are characterized by very fast electromechanical transients, their accurate analysis requires strong coupling between the equations governing the electrical and the mechanical behaviors. The device is investigated by using a dedicated numerical code capable to take into account eddy currents, compensating windings, as well as the excitation/control circuits. Furthermore, the code is capable of modeling centrifugal forces and vibrations acting on the shaft due to electric and mechanical unbalances or to misalignments of the shaft from its centered position. This makes the code a very power…
Targeting Alzheimer’s disease with multimodal polypeptide-based nanoconjugates
2021
LRP1-targeted St-Cl–polyglutamate conjugates as multivalent neuroprotective/neurotrophic therapeutics for Alzheimer’s disease.
On the formation of inclusion complexes at the solid/liquid interface of anchored temperature-responsive PNIPAAM diblock copolymers with γ-cyclodextr…
2017
The thermal responsive behavior of adsorbed layers of diblock copolymers of poly(N-isopropylacrylamide) (PNIPAAM) and poly((3-acrylamidopropyl)trimethylammonium chloride) (PAMPTMA(+)) with γ-cyclodextrin (γ-CD) at the solid/liquid interface has been investigated using three in situ techniques: null ellipsometry, quartz–crystal microbalance with dissipation monitoring, and neutron reflectometry. The measurements provided information about the adsorbed amounts, the layer thickness, hydration and viscoelastic properties, and the interfacial structure and composition. The copolymers adsorb to silica with the cationic PAMPTMA(+) blocks sitting as anchors in a flat conformation and the PNIPAAM ch…
Negative Staining and Cryo-negative Staining: Applications in Biology and Medicine
2013
Negative staining is widely applicable to isolated viruses, protein molecules, macromolecular assemblies and fibrils, subcellular membrane fractions, liposomes and artificial membranes, synthetic DNA arrays, and also to polymer solutions and a variety of nanotechnology samples. Techniques are provided for the preparation of the necessary support films (continuous carbon and holey/perforated carbon). The range of suitable negative stains is presented, with some emphasis on the benefit of using ammonium molybdate and of negative stain-trehalose combinations. Protocols are provided for the single droplet negative staining technique (on continuous and holey carbon support films), the floating a…
On Combinatorial Generation of Prefix Normal Words
2014
A prefix normal word is a binary word with the property that no substring has more 1s than the prefix of the same length. This class of words is important in the context of binary jumbled pattern matching. In this paper we present an efficient algorithm for exhaustively listing the prefix normal words with a fixed length. The algorithm is based on the fact that the language of prefix normal words is a bubble language, a class of binary languages with the property that, for any word w in the language, exchanging the first occurrence of 01 by 10 in w results in another word in the language. We prove that each prefix normal word is produced in O(n) amortized time, and conjecture, based on expe…
Stimulated emission and optical properties of pyranyliden fragment containing compounds in PVK matrix
2017
This work has been supported by National Research program “Multifunctional materials and composites, photonics and nanotechnology (IMIS2)”. Financial support provided by Scientific Research Project for Students and Young Researchers No. SJZ2015/12 realised at the Institute of Solid State Physics, University of Latvia is greatly acknowledged.
Emerging contributions of formyl peptide receptors to neurodegenerative diseases.
2021
Abstract Inflammation is a central element of many neurodegenerative diseases. Formyl peptide receptors (FPRs) can trigger several receptor-dependent signal transduction pathways that play a key role in neuroinflammation and neurodegeneration. They are chemotactic receptors that help to regulate pro- and anti-inflammatory responses in most mammals. FPRs are primarily expressed in the immune and nervous systems where they interact with a complex pattern of pathogen-derived and host-endogenous molecules. Mounting evidence points towards a contribution of FPRs – via neuropathological ligands such as Amyloid beta, and neuroprotective ligands such as Humanin, Lipoxin A4, and Annexin A1 – to mult…
Polysorbate 80 controls Morphology, structure and stability of human insulin Amyloid-Like spherulites
2022
AbstractAmyloid protein aggregates are not only associated with neurodegenerative diseases and may also occur as unwanted by-products in protein-based therapeutics. Surfactants are often employed to stabilize protein formulations and reduce the risk of aggregation. However, surfactants alter protein-protein interactions and may thus modulate the physicochemical characteristics of any aggregates formed. Human insulin aggregation was induced at low pH in the presence of varying concentrations of the surfactant polysorbate 80. Various spectroscopic and imaging methods were used to study the aggregation kinetics, as well as structure and morphology of the formed aggregates. Molecular dynamics s…