Search results for " Formation"

Alternative pathway activation of T cells by binding of CD2 to its cell-surface ligand.

1987

Activation of resting T lymphocytes is initiated by the interaction of cell-surface receptors with their corresponding ligands. In addition to activation through the CD3 (T3)-Ti antigen-receptor complex1, recent experiments have demonstrated induction of T-cell proliferation through the CD2 (T11) molecule2–4, traditionally known as the erythrocyte(E)-receptor, through which T cells can bind red blood cells (RBC)5–7. This 'alternative pathway' of T-cell activation2 was observed in vitro in response to combinations of anti-CD2 monoclonal antibodies (mAbs) that bind to distinct epitopes of CD2, such as mAbs against T112 plus T113 (ref. 2). The physiological importance of this activation pathwa…

Functional role of the low-density lipoprotein receptor-related protein in Alzheimer's disease.

2006

Alzheimer’s disease (AD) is the most common age-related neurodegenerative disorder, characterized by neuronal loss, neurofibrillary tangle formation and the extracellular deposition of amyloid-β (Aβ) plaques. The amyloid precursor protein (APP) and the enzymes responsible for Aβ generation seem to be the base elements triggering the destructive processes. Initially, the low-density lipoprotein receptor-related protein (LRP) was genetically linked to AD and later it emerged to impact on many fundamental events related to this disease. LRP is not only involved in Aβ clearance but is also the major receptor of several AD-associated ligands, e.g. apolipoprotein E and α<sub>2</sub>-m…

Numerical Study of Blow-Up Mechanisms for Davey-Stewartson II Systems

2018

We present a detailed numerical study of various blow-up issues in the context of the focusing Davey-Stewartson II equation. To this end we study Gaussian initial data and perturbations of the lump and the explicit blow-up solution due to Ozawa. Based on the numerical results it is conjectured that the blow-up in all cases is self similar, and that the time dependent scaling is as in the Ozawa solution and not as in the stable blow-up of standard $L^{2}$ critical nonlinear Schr\"odinger equations. The blow-up profile is given by a dynamically rescaled lump.

On the number of solutions of a Duffing equation

1991

The exact number of solutions of a Duffing equation with small forcing term and homogeneous Neumann boundary conditions is given. Several bifurcation diagrams are shown.

Les procédures d'orientation dans le système scolaire et leurs implications dans la compréhension des relations entre la formation et l'emploi

1981

International audience; Le texte ci-après cherche à explorer en quoi les procédures d'orientation qui sont fondamentales dans la constitution de la segmentation de la population scolaire sont importantes pour la compréhension des phénomènes d'orientation. Il comprend trois parties. La première propose une réflexion d'ordre théorique sur l'orientation au niveau de la classe de 3ème et tente de poser des questions objectives, ayant un contenu empirique opératoire. La seconde partie donne des éléments empiriques sur l'orientation à la fin de La c lasse de 3ème. L'ensemble des questions posées dans la première partie aurait dû y trouver une réponse. Toutefois, des raisons techniques ont retardé…

Le procédures d'orientation dans le système scolaire et leurs implications dans la compréhension des relations entre la formation et l'emploi - 3ème …

1981

International audience

Étude sur les réformes curriculaires par l'approche par compétences en Afrique

2009

Cette étude vise trois objectifs : réaliser un état des lieux des processus de réformes curriculaires en éducation de base en Afrique pour identifier les problèmes rencontrés, les résultats positifs et les "bonnes pratiques", aider les responsables des systèmes éducatifs à prendre des mesures pertinentes et accompagner les réformes et enfin aider les bailleurs de fonds à mieux comprendre les effets de leur aide et à mieux cibler les projets de réforme en termes de coût et d'efficacité à tous les niveaux des systèmes éducatifs impliqués.

L'accompagnement au projet professionnel des demandeurs d'emploi éloignés de l'emploi au prisme du territoire

2023

Enthalpies of mixing of some nitriles aqueous solutions with dodecylsurfactants micellar solutions

1988

The enthalpies of mixing of some n-nitriles (from acetonitrile to valeronitrile) aqueous solutions with dodecyltzimethylammonium bromide, sodium dodecylsulfate and dodecyltzimethylammonium oxide micellar solutions were determined. The measurements were performed by systematically changing the surfactant concentration at a given solute concentration. The experimental enthalpies were rationalized in terms of the standard enthalpy of transfer of solute from the aqueous to the micellar phase and of the distribution constant between the two phase. Information on the effect of the nature of the surfactant on the standard thermodynamic quantities of transfer(ΔG t o , ΔH t o , TΔS t o ) is reported…

Protonation thermodynamics of 2,2'-bipyridyl in aqueous solution. Salt effects and weak complex formation

1993

Abstract Protonation constants of 2,2'-bipyridyl (bipy) have been determined potentiometrically, using (H + )-glass electrode, in different aqueous media (alkali and alkaline earth chlorides, tetramethylammonium chloride and tetramethylammonium iodide) at different temperatures and ionic strengths. The differences in log K H values are explained using a complex formation model. Formation thermodynamic parameters are given.