Search results for " Frailty"

showing 10 items of 79 documents

Longitudinal Association Between Physical Activity and Frailty Among Community-Dwelling Older Adults

2020

Objectives: To examine the longitudinal association between frequency of moderate physical activity (PA) and overall, physical, psychological, and social frailty among community-dwelling older adults older than 70 years. Second, we assessed the association between a 12-month change in frequency of moderate PA and frailty. Design: Longitudinal cohort study. Setting: Community settings in Spain, Greece, Croatia, the Netherlands, and the United Kingdom. Participants: A total of 1735 participants (61.1% female ; mean age = 79.6 years ; SD = 5.5 years). Measurements: The frequency of self-reported moderate PA was measured and classified into two categories: "regular frequency" and "low frequency…

MaleRegular Issue ContentFrail ElderlyPhysical activityClinical Investigationsphysical activityfrailtyphysical frailty03 medical and health sciences0302 clinical medicineBIOMEDICINA I ZDRAVSTVO. Javno zdravstvo i zdravstvena zaštita.Regular frequencySurveys and QuestionnairesMedicineHumanssocial frailty.030212 general & internal medicineClinical InvestigationLongitudinal StudiesLongitudinal cohortAssociation (psychology)Setting communityExerciseAgedbusiness.industryBIOMEDICINE AND HEALTHCARE. Public Health and Health Care.Mean ageConfidence intervalEuropefrailty ; physical activity ; physical frailty ; psychological frailty ; social frailty.psychological frailtyFemaleIndependent LivingSelf ReportGeriatrics and Gerontologysocial frailtybusiness030217 neurology & neurosurgeryDemographyJournal of the American Geriatrics Society
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Angiotensin-Converting Enzyme Inhibitor Use and Incident Frailty: A Longitudinal Cohort Study

2019

Introduction: Angiotensin-converting enzyme inhibitors (ACEI) may have several pleiotropic effects, but the literature regarding a possible relationship between ACEI use and frailty is limited. We investigated whether ACEI use is associated with lower risk of frailty in a cohort of North American individuals. Methods: Data from the Osteoarthritis Initiative, a cohort study with 8 years of follow-up including community-dwelling adults with knee osteoarthritis or at high risk for this condition, were analyzed. ACEI use was defined through self-reported information and confirmed by a trained interviewer. Frailty was defined using the Study of Osteoporotic Fracture (SOF) index as the presence o…

MaleRiskmedicine.medical_specialtyA Longitudinal Cohort Study.- Drugs & aging cilt.36 ss.387-393 2019 [VERONESE N. STUBBS B. SMITH L. MAGGI S. JACKSON S. Soysal P. DEMURTAS J. CELOTTO S. KOYANAGI A. -Angiotensin-Converting Enzyme Inhibitor Use and Incident Frailty]Angiotensin-Converting Enzyme InhibitorsLower riskCohort Studies03 medical and health sciencessymbols.namesake0302 clinical medicineInternal medicineWeight LossmedicineHumansPharmacology (medical)Longitudinal Studiescardiovascular diseases030212 general & internal medicinePoisson regressionPropensity ScoreAgedFrailtybusiness.industryConfoundingMiddle AgedOsteoarthritis KneeConfidence intervalcarboxypeptidasecaptoprilinhibitorRelative riskNorth AmericaPropensity score matchingCohortsymbolsFemaleIndependent LivingSelf ReportGeriatrics and Gerontologybusinessdipeptidyl030217 neurology & neurosurgeryCohort studyDrugs & Aging
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<p>Agreement of a Short Form of the Self-Administered Multidimensional Prognostic Index (SELFY-MPI-SF): A Useful Tool for the Self-Assessment o…

2020

Alberto Cella,1 Alberto Ferrari,2 Giuseppe Rengo,3 Vincenzo Solfrizzi,4 Nicola Veronese,5 Matteo Puntoni,6 Sabrina Zora,1 Alberto Pilotto,1,4 Filippo Fimognari7 On behalf of the SELFY-MPI SIGOT Investigators1Geriatric Unit, Department of Geriatric Care, Orthogeriatrics and Rehabilitation, EO Galliera Hospital, Genova, Italy; 2Geriatric Unit, Arcispedale S. Maria Nuova, AUSL Reggio Emilia, Reggio Emilia, Italy; 3Department of Translational Medical Sciences, Division of Geriatrics, Federico II University, Napoli, Italy; 4Department of Interdisciplinary Medicine, University of Bari, Bari, Italy; 5Primary Care Department, Azienda ULSS 3 Serenissima, Venice, Italy; 6Scientific Coordination Unit,…

MaleSelf-assessmentGerontologySelf-AssessmentIndex (economics)Activities of daily livingInterpersonal RelationReproducibility of ResultNutritional StatusSample (statistics)Comorbidity03 medical and health sciencesCognition0302 clinical medicineRisk Factorsself assessmentActivities of Daily LivingHumansMedicineInterpersonal Relations030212 general & internal medicineGeriatric AssessmentAgedOriginal ResearchAged 80 and overFrailtybusiness.industryRisk FactorSelfReproducibility of ResultsCognitionGeneral MedicineMiddle AgedPhysical Functional Performancecomprehensive geriatric assessmentmedicine.diseaseComorbiditymultidimensional prognostic indexNutritional StatuClinical Interventions in AgingPolypharmacyFemaleIndependent LivingGeriatrics and GerontologybusinessOlder peoplecomprehensive geriatric assessment multidimensional prognostic index frailty self assessmen030217 neurology & neurosurgeryHumanClinical Interventions in Aging
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Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort…

2021

Abstract Background The Clinical Frailty Scale (CFS) is frequently used to measure frailty in critically ill adults. There is wide variation in the approach to analysing the relationship between the CFS score and mortality after admission to the ICU. This study aimed to evaluate the influence of modelling approach on the association between the CFS score and short-term mortality and quantify the prognostic value of frailty in this context. Methods We analysed data from two multicentre prospective cohort studies which enrolled intensive care unit patients ≥ 80 years old in 26 countries. The primary outcome was mortality within 30-days from admission to the ICU. Logistic regression models for…

MaleShort term mortalityCritical Care and Intensive Care MedicineCohort Studies0302 clinical medicinekwetsbaarheidMedicine and Health Sciences80 and overMedicine610 Medicine & healthProspective cohort studyCorrelation of Data11 Medical and Health SciencesAged 80 and overOUTCOMESIntensive care unitsFrailtyVIP1Aged&nbspMedical emergencies. Critical care. Intensive care. First aidScale (social sciences)Femaleprospectief onderzoekLife Sciences & BiomedicineCRITICALLY-ILL PATIENTS 80 and overStudy groupsmedicine.medical_specialtyAnestesi och intensivvård80 jaar en ouder610 Medicine & healthINTENSIVE-CAREBED AVAILABILITYNO03 medical and health sciencesCritical Care MedicineIntensive caresterfteGeneral & Internal MedicineHumansIntensive care units; Aged; 80 and over; Frailty; Prospective studies; MortalityIn patientddc:610Aged 80 and over; Frailty; Intensive care units; Mortality; Prospective studies; Aged 80 and over; Cohort Studies; Correlation of Data; Female; Frailty; Humans; Intensive Care Units; Logistic Models; Male; Mortality; Prospective StudiesMortalityAgedScience & TechnologyAnesthesiology and Intensive Carebusiness.industryRC86-88.9Research030208 emergency & critical care medicineADULTSAged 80 and over; Frailty; Intensive care units; Mortality; Prospective studies;Emergency & Critical Care MedicineLogistic Models030228 respiratory systemintensivecareafdelingenAged 80 and overCritical illnessEmergency medicineVIP2 study group&nbspCRITICAL ILLNESSbusinessProspective studies
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The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years)

2017

Purpose: Very old critical ill patients are a rapid expanding group in the ICU. Indications for admission, triage criteria and level of care are frequently discussed for such patients. However, most relevant outcome studies in this group frequently find an increased mortality and a reduced quality of life in survivors. The main objective was to study the impact of frailty compared with other variables with regards to short-term outcome in the very old ICU population. Methods: A transnational prospective cohort study from October 2016 to May 2017 with 30 days follow-up was set up by the European Society of Intensive Care Medicine. In total 311 ICUs from 21 European countries participated. Th…

MaleTime FactorsOutcome AssessmentFrail Elderly/statistics & numerical data[SDV]Life Sciences [q-bio]HSJ UCIPassiveCritical Care and Intensive Care MedicineFrailty/classification/diagnosis/mortality/therapySeverity of Illness IndexSeverity of illneElderly0302 clinical medicineQuality of lifeElderly; Frailty; ICU; Mortality; Octogenarians; Severity of illness; Aged 80 and over; Critical Illness; Europe; Euthanasia Passive; Female; Frail Elderly; Frailty; Geriatric Assessment; Humans; Intensive Care Units; Length of Stay; Male; Outcome Assessment Health Care; Proportional Hazards Models; Prospective Studies; Quality of Life; Severity of Illness Index; Time Factors; Hospital MortalityOutcome Assessment Health Care80 and overProspective StudiesHospital Mortality030212 general & internal medicineProspective cohort studyAged 80 and overeducation.field_of_studyddc:617FrailtyMortality rate[SDV] Life Sciences [q-bio]EuropeIntensive Care UnitsLength of Stay/statistics & numerical dataCohortIntensive Care Units/statistics & numerical dataCritical IllneFemaleSOFA scoreHumanmedicine.medical_specialtyOctogenariansTime FactorCritical IllnessFrail ElderlyIntensive Care UnitPopulationINTENSIVE-CARESeverity of illnessEurope/epidemiologyOutcome Assessment (Health Care)03 medical and health sciencesOctogenarianIntensive careSeverity of illnessJournal ArticlemedicineHumansCOHORTMortalityOctogenarinansIntensive care medicineeducationGeriatric AssessmentAgedProportional Hazards ModelsOLDEREuthanasiabusiness.industry030208 emergency & critical care medicineLength of StayEuthanasia PassiveHealth CareProspective StudieCritical Illness/mortalityUNITICUEmergency medicineProportional Hazards ModelQuality of LifebusinessIntensive Care Medicine
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Three Decades of Comprehensive Geriatric Assessment: Evidence Coming From Different Healthcare Settings and Specific Clinical Conditions

2017

Comprehensive geriatric assessment (CGA) is a multidisciplinary diagnostic and treatment process that identifies medical, psychosocial, and functional capabilities of older adults to develop a coordinated plan to maximize overall health with aging. Specific criteria used by CGA programs to evaluate patients include age, medical comorbidities, psychosocial problems, previous or predicted high healthcare utilization, change in living situation, and specific geriatric conditions. However, no universal criteria have been agreed upon to readily identify patients who are likely to benefit from CGA. Evidence from randomized controlled trials and large systematic reviews and meta-analyses suggested…

Maleendocrine systemmedicine.medical_specialtyHistory 21st Centurylaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled trialMultidisciplinary approachlawemergency medicineHealth careHumansMedicinecancerCognitive DysfunctionMusculoskeletal Diseases030212 general & internal medicineIntensive care medicineGeriatric AssessmentGeneral NursingHealth policyNursing (all)2901 Nursing (miscellaneous)Agedcognitive impairmentAged 80 and overGeriatricsgeriatricsFrailtybusiness.industrycancer; cognitive impairment; emergency medicine; Frailty; geriatrics; orthopedics; Nursing (all)2901 Nursing (miscellaneous); Medicine (all); Health PolicyMedicine (all)Health PolicyGeriatric assessmentGeneral MedicineHistory 20th CenturySystematic reviewFrailty cancer cognitive impairment emergency medicine geriatrics orthopedicsPhysical therapyorthopedicsFemaleHealth FacilitiesGeriatrics and GerontologybusinessPsychosocial030217 neurology & neurosurgery
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THE RELATIONSHIP BETWEEN THE DIETARY INFLAMMATORY INDEX AND INCIDENT FRAILTY: A LONGITUDINAL COHORT STUDY

2017

Objective:\ud \ud Inflammation is key risk factor for several conditions in the elderly. However, the relationship between inflammation and frailty is still unclear. We investigated whether higher dietary inflammatory index (DII) scores were associated with higher incidence of frailty in a cohort of North Americans.\ud \ud Design:\ud \ud Longitudinal, with a follow-up of 8 years.\ud \ud Setting:\ud \ud Osteoarthritis Initiative.\ud \ud Participants:\ud \ud A total of 4421 participants with, or at high risk of, knee osteoarthritis.\ud \ud Measurements:\ud \ud DII scores were calculated using the validated Block Brief 2000 Food-Frequency Questionnaire and categorized into sex-specific quartil…

Malemedicine.medical_specialtyAged; dietary inflammatory index; frailty; inflammationFrail Elderly030209 endocrinology & metabolismfrailtyRisk AssessmentArticleCohort Studies03 medical and health sciencesSex Factors0302 clinical medicineWeight lossInternal medicinemedicineHumans030212 general & internal medicineLongitudinal StudiesRisk factorGeriatric AssessmentGeneral NursingProportional Hazards ModelsAgedAged 80 and overFrailtybusiness.industryIncidenceHealth PolicyIncidence (epidemiology)Hazard ratioConfoundingAge FactorsGeneral MedicineOsteoarthritis KneePrognosisConfidence intervalDietQuartileinflammationNorth AmericaCohortPhysical therapydietary inflammatory indexFemaleIndependent LivingGeriatrics and Gerontologymedicine.symptombusinessOsteoporotic Fractures
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Frailty and Risk of Cardiovascular Diseases in Older Persons: The Age, Gene/Environment Susceptibility-Reykjavik Study

2017

Frailty is a risk factor for cardiovascular diseases (CVD), but the studies available have not considered the presence of subclinical atherosclerotic disease as potential confounders. We investigated the association between frailty and the onset of CVD independently of subclinical atherosclerotic disease. For this reason, a sample of 3818 older participants participating in the Age, Gene/Environment Susceptibility-Reykjavik Study without CVD at baseline was followed for a median of 8.7 years. Frailty was defined as the presence of ≥3 among five Fried's criteria (unintentional weight loss, low physical activity level, weakness, exhaustion, and slow gait speed). Incident CVD was defined as on…

Malemedicine.medical_specialtyFrail Elderlyaging; cardiovascular disease; frailty; risk factorfrailty030204 cardiovascular system & hematologyCoronary artery disease03 medical and health sciences0302 clinical medicineWeight lossRisk Factorscardiovascular diseaseInternal medicinemedicineHumanscardiovascular disease risk factor aging frailtyGenetic Predisposition to Disease030212 general & internal medicinecardiovascular diseasesRisk factorStrokeSubclinical infectionAgedbusiness.industryIncidence (epidemiology)IncidenceagingOriginal Articlesmedicine.disease3. Good healthIntima-media thicknessrisk factorCardiovascular DiseasesHeart failurePhysical therapyFemaleGene-Environment InteractionGeriatrics and Gerontologymedicine.symptombusinessFollow-Up Studies
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Relationship between multidimensional prognostic index and incident depressive symptoms in older people: Findings from the Irish Longitudinal Study o…

2020

Objectives: The multidimensional prognostic index (MPI) is a useful prognostic tool for evaluating adverse health outcomes in older individuals. However, the association between MPI and depressive symptoms has never been explored, despite depression being a common condition in older people. We therefore aimed to evaluate whether MPI may predict incident depressive symptoms. Methods: Longitudinal, cohort study, with 2 years of follow-up (W1: October 2009-February 2011; W2: April 2012-January 2013), including people aged ≥65 years without depressive symptoms at baseline. A comprehensive geriatric assessment including information on functional, nutritional, cognitive status, mobility, comorbid…

Malemedicine.medical_specialtyLongitudinal studyAgingfrailtyLogistic regressionCohort StudiesInternal medicineEpidemiologyMedicineHumansLongitudinal StudiesGeriatric AssessmentDepression (differential diagnoses)AgedAged 80 and overbusiness.industryDepressionOdds ratioPrognosismultidimensional prognostic indexConfidence intervalPsychiatry and Mental healthAgeingdepressiondepression frailty Ireland multidimensional prognostic index.FemaleGeriatrics and GerontologybusinessIrelandCohort studyInternational journal of geriatric psychiatryREFERENCES
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“Ageism” Is Associated With Self-Reported Multidimensional Frailty in Community-Dwelling Older Subjects: A Population-Based Study

2022

Ageism is a stereotyping, prejudice and discrimination against people, based on age. Ageism may impact the quality of life and the care of older people, a problem that can be greater when the older person is “frail.” However, few studies explored the role of frailty as a factor related to ageism. The aim of this study was to assess the association between perceived age discrimination (PAD), i.e., ageism, and multidimensional frailty in a cohort of community-dwelling older adults. We enrolled 1,337 community-dwelling subjects over-65 years that filled out a structured questionnaire to collect psycho-socio-economic and behavioral information. Multidimensional frailty was assessed by the SELFY…

Medicine (General)frailtyGeneral MedicineAgeism; frailty; older people; Inequalityperceived age discrimination self-assessed frailty multidimensional prognostic index older epidemiologymultidimensional prognostic indexAgeismolder peopleR5-920Inequalityself-assessed frailtyolderperceived age discriminationepidemiologyFrontiers in Medicine
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