Search results for " INTERPRETATION"
showing 10 items of 555 documents
Translating Transculturality: Mediation of Identity in John Rabe’s Diaries
2019
Along with people’s movement and technology, local and foreign components in language and culture become interconnected. Hence translation and cultural studies need approaches, beyond the national, to fuzzy linguistic and cultural forms. One such case originates from the Nanking Massacre, which occurred in the East Asian theatre of WWII. John Rabe, a businessman from Hamburg and a foreign resident in Nanking, was elected by the International Committee for the Nanking Safety Zone to be its chairman. His humanitarian efforts eventually won him a special cultural identity, «the Living Buddha». This article focuses on mediation of identity. It presents «translating transculturality» as a new re…
Safety and Pharmacokinetics of Glecaprevir/Pibrentasvir in Adults With Chronic Genotype 1–6 Hepatitis C Virus Infections and Compensated Liver Disease
2019
Background: Untreated, chronic hepatitis C virus (HCV) infection may lead to progressive liver damage, which can be mitigated by successful treatment. This integrated analysis reports the safety, efficacy, and pharmacokinetics (PK) of the ribavirin-free, direct-acting, antiviral, fixed-dose combination of glecaprevir/pibrentasvir (G/P) in patients with chronic HCV genotype 1-6 infections and compensated liver disease, including patients with chronic kidney disease stages 4 or 5 (CKD 4/5). Methods: Data from 9 Phase II and III clinical trials, assessing the efficacy and safety of G/P treatment for 8-16 weeks, were included. The presence of cirrhosis was determined at screening using a liver …
New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology
2019
The American Society for Pharmacology and Experimental Therapeutics has revised the Instructions to Authors for Drug Metabolism and Disposition, Journal of Pharmacology and Experimental Therapeutics, and Molecular Pharmacology These revisions relate to data analysis (including statistical analysis) and reporting but do not tell investigators how to design and perform their experiments. Their overall focus is on greater granularity in the description of what has been done and found. Key recommendations include the need to differentiate between preplanned, hypothesis-testing, and exploratory experiments or studies; explanations of whether key elements of study design, such as sample size and …
A completely automated CAD system for mass detection in a large mammographic database.
2006
Mass localization plays a crucial role in computer-aided detection (CAD) systems for the classification of suspicious regions in mammograms. In this article we present a completely automated classification system for the detection of masses in digitized mammographic images. The tool system we discuss consists in three processing levels: (a) Image segmentation for the localization of regions of interest (ROIs). This step relies on an iterative dynamical threshold algorithm able to select iso-intensity closed contours around gray level maxima of the mammogram. (b) ROI characterization by means of textural features computed from the gray tone spatial dependence matrix (GTSDM), containing secon…
Exudate-based diabetic macular edema detection in fundus images using publicly available datasets
2010
International audience; Diabetic macular edema (DME) is a common vision threatening complication of diabetic retinopathy. In a large scale screening environment DME can be assessed by detecting exudates (a type of bright lesions) in fundus images. In this work, we introduce a new methodology for diagnosis of DME using a novel set of features based on colour, wavelet decomposition and automatic lesion segmentation. These features are employed to train a classifier able to automatically diagnose DME through the presence of exudation. We present a new publicly available dataset with ground-truth data containing 169 patients from various ethnic groups and levels of DME. This and other two publi…
La portada de la iglesia de las Escuelas Pías de Gandía. Su proceso constructivo y modulación arquitectónico-musical
2020
The facade of the church of the Pious Schools of Gandia has not attracted the attention of researchers. However, its conception has a great architectural culture and constitutes an essential work to understand its context, fundamentally, that of the theoretical treatises of the Renaissance. From this study it is wanted to value its architecture and that it is considered as an outstanding ingredient to know its period of construction in general and jesuit architecture in particular. For its understanding, its interpretation in the culture of contemporary architecture treaties and, especially, in the architectural-musical theory of Leon Battista Alberti will be necessary.. La portada de la ig…
An automated image analysis methodology for classifying megakaryocytes in chronic myeloproliferative disorders
2008
This work describes an automatic method for discrimination in microphotographs between normal and pathological human megakaryocytes and between two kinds of disorders of these cells. A segmentation procedure has been developed, mainly based on mathematical morphology and wavelet transform, to isolate the cells. The features of each megakaryocyte (e.g. area, perimeter and tortuosity of the cell and its nucleus, and shape complexity via elliptic Fourier transform) are used by a regression tree procedure applied twice: the first time to find the set of normal megakaryocytes and the second to distinguish between the pathologies. The output of our classifier has been compared to the interpretati…
Computer-aided system for morphometric mandibular index computation (Using dental panoramic radiographs)
2012
Objective: We propose and validate a computer—aided system to measure three different mandibular indexes: cortical width, panoramic mandibular index and, mandibular alveolar bone resorption index. Study Design: Repeatability and reproducibility of the measurements are analyzed and compared to the manual estimation of the same indexes. Results: The proposed computerized system exhibits superior repeatability and reproducibility rates compared to standard manual methods. Moreover, the time required to perform the measurements using the proposed method is negligible compared to perform the measurements manually. Conclusions: We have proposed a very user friendly computerized method to measure …
Novel technologies to detect atelectotrauma in the injured lung
2010
ABSTRACTCyclical recruitment and derecruitment of lung parenchyma (R/D) remains a serious problem in ALI/ARDS patients, defined as atelectotrauma. Detection of cyclical R/D to titrate the optimal respiratory settings is of high clinical importance. Image-based technologies that are capable of detecting changes of lung ventilation within a respiratory cycle include dynamic computed tomography (dCT), synchrotron radiation computed tomography (SRCT), and electrical impedance tomography (EIT). Time-dependent intra-arterial oxygen tension monitoring represents an alternative approach to detect cyclical R/D, as cyclical R/D can result in oscillations of PaO2 within a respiratory cycle. Continuous…
Revista española de educación comparada
2019
espanolEl objetivo de este trabajo consiste en aplicar la dialectica analogica desarrollada por Platon como una metodologia adecuada para comprender su pensamiento. En este sentido, abordare en primer lugar las aclaraciones terminologicas necesarias para delimitar el planteamiento de la cuestion y prestar una especial atencion a la nocion de symploke introducida por Platon y desarrollada posteriormente por Jesus G. Maestro como uno de los criterios hermeneuticos centrales que la Critica de la literatura debe tener en cuenta para evitar caer en el univocidad interpretativa o en la equivocidad propia de la postmodernidad. En segundo lugar, realizare una aproximacion metodologica a la lectura …