Search results for " Intensive care Unit"

showing 10 items of 139 documents

Outbreak of colonizations by extended-spectrum β-lactamase-producing Escherichia coli sequence type 131 in a neonatal intensive care unit, Italy

2013

Abstract Background Extended spectrum β-lactamases (ESBLs) often associated with resistance to aminoglycosides and fluoroquinolones have recently emerged in community-associated Escherichia coli. The worldwide clonal dissemination of E. coli sequence type (ST)131 is playing a prominent role. We describe an outbreak of colonizations by ESBL-producing E. coli (ESBL-E. coli) in the neonatal intensive care unit (NICU) of the University Hospital, Palermo, Italy. Methods An epidemiological investigation was conducted with the support of molecular typing. All children admitted to the NICU and colonized by ESBL-E. coli between January and June 2012, were included in the study. Cases were defined as…

Microbiology (medical)NICUmedicine.medical_specialtyNeonatal intensive care unitST131business.industryTransmission (medicine)EpidemiologyResearchPublic Health Environmental and Occupational HealthOutbreakDrug resistancemedicine.disease_causeMicrobiologyInfectious DiseasesMedical microbiologyEpidemiologymedicineInfection controlmulti-drug resistance E.coli ESBLPharmacology (medical)ESBL-Escherichia colibusinessEscherichia coliAntimicrobial Resistance and Infection Control
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Microsatellite-based genotyping of Candida parapsilosis sensu stricto isolates reveals dominance and persistence of a particular epidemiological clon…

2012

In this study, using multilocus microsatellite analysis, we report the genetic characterization of 27 Candida parapsilosis isolates recovered in two different periods of time (2007-2009 and 2011-2012) from infants hospitalized in the neonatal intensive care unit of a hospital in Messina, Italy. The results revealed the persistence and dominance of a particular infectious genotype among NICU patients and highlight the power of the used microsatellite markers in clarifying epidemiologic associations, detect micro-evolutionary variations and facilitating the recognition of outbreaks. © 2012 Elsevier B.V.

Microbiology (medical)medicine.medical_specialtyCandida parapsilosisNeonatal intensive care unitGenotypeSettore MED/17 - Malattie InfettiveInfectious DiseaseCandida parapsilosisMicrobiologyDisease OutbreaksCandida orthopsilosisGeneticCandida orthopsilosiIntensive Care Units NeonatalEpidemiologyGenotypeGeneticsmedicineHumansMolecular BiologyGenotypingEcology Evolution Behavior and SystematicsCandidaDominance (genetics)ITS-sequencingGeneticsCross InfectionDisease OutbreakbiologyCandidiasisInfant NewbornOutbreakCandida metapsilosisbiology.organism_classificationCandida parapsilosis; Candida orthopsilosis; Candida metapsilosis; Molecular epidemiology; ITS-sequencing; Microsatellite genotypingEcology Evolution Behavior and SystematicCandida metapsilosiInfectious DiseasesMolecular epidemiologyCandidiasiCandida parapsilosiMicrosatellite RepeatMicrosatelliteMicrosatellite genotypingMicrosatellite RepeatsHumanMultilocus Sequence TypingInfection, Genetics and Evolution
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Evaluation of microbiological screening in a neonatal intensive care unit to optimize empiric antibiotic use.

2019

Microbiology (medical)medicine.medical_specialtyNeonatal intensive care unitBacteriabusiness.industryMEDLINEInfant NewbornRectumGeneral MedicineBacterial InfectionsMicrobial Sensitivity TestsAnti-Bacterial AgentsTertiary Care CentersInfectious DiseasesIntensive Care Units NeonatalmedicineHumansMass ScreeningPharynxAntibiotic useIntensive care medicinebusinessMass screeningThe Journal of hospital infection
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Epidemic spread of ST1-MRSA-IVa in a neonatal intensive care unit, Italy

2012

Abstract Background Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has recently emerged as an important pathogen in neonatal intensive care units (NICUs). The purposes of this study were to characterize methicillin-resistant isolates from an outbreak in a NICU, to examine the genetic traits and clonality of CA-MRSA, and to review the characteristics and outcomes of the neonatal cases and investigate the routes of entry and transmission of the MRSA outbreak strain in the NICU under study. Methods The study NICU practiced an active surveillance program for multidrug-resistant organisms, including weekly cultures for detection of MRSA from nasal swabs among all the …

NICUMaleMethicillin-Resistant Staphylococcus aureusPediatricsmedicine.medical_specialtyMRSA intensive care unitNeonatal intensive care unitEpidemiologyCA-MRSAMicrobial Sensitivity Testsmedicine.disease_causeStaphylococcal infectionslaw.inventionDisease OutbreakslawIntensive careIntensive Care Units NeonatalmedicineInfection controlHumansPediatrics Perinatology and Child HealthCross InfectionInfection ControlTransmission (medicine)business.industrylcsh:RJ1-570Infant NewbornOutbreaklcsh:PediatricsStaphylococcal Infectionsmedicine.diseaseIntensive care unitMethicillin-resistant Staphylococcus aureusBacterial Typing TechniquesCommunity-Acquired InfectionsItalyPediatrics Perinatology and Child HealthEmergency medicineFemalebusinessResearch ArticleBMC Pediatrics
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The parent-nurse relationship in the neonatal intensive care unit context - closeness and emotional involvement

2008

Aim and background:  Family-centred care, which acknowledges parents as partners in care, is a desirable and essential part of neonatal nursing. There has been extensive research on parents’ experiences of parenting in neonatal intensive care units (NICU), but there is little research on nurses’ experiences of being in these enduring close relationships. The aim of this paper is to explore parents’ and nurses’ experiences of the close parent–nurse relationship when a premature child is hospitalized. Method:  The design was exploratory with a hermeneutic approach. The methods used were participant observation and in-depth interviews with six mothers, six fathers and six nurses in a Norwegian…

Neonatal intensive care unitClosenessPublic Health Environmental and Occupational HealthContext (language use)Participant observationNorwegianlanguage.human_languageDevelopmental psychologyNursingIntensive carelanguageNeonatal nursingPsychologyDeclaration of HelsinkiScandinavian Journal of Caring Sciences
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Nurses' experiences by using heated humidified high flow cannula to premature infants versus nasal continuous positive airway pressure

2016

Abstract Background Some premature infants are now being treated with heated humidified high flow nasal cannula (HHHFNC) instead of nasal continuous positive airway pressure (nCPAP). Purpose To explore nurses' experiences of using HHHFNC compared with nCPAP for premature infants. Method Six qualitative in-depth interviews were completed with nurses at two different newborn intensive care units. Results Preterm infants showed greater satisfaction with HHHFNC than nasal continuous positive airway pressure. HHHFNC was also associated with fewer pressure injuries and less facial discomfort, and an increased bonding between baby and parent. However, HHHFNC gave less ventilation support than nCPA…

Neonatal intensive care unitbusiness.industrymedicine.medical_treatmentmedicine.disease_causePediatricsCannulalaw.invention03 medical and health sciences0302 clinical medicinelaw030225 pediatricsAnesthesiaVentilation (architecture)medicine030212 general & internal medicineContinuous positive airway pressureHigh flowbusinessNasal cannulaJournal of Neonatal Nursing
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Bedside surgery in the newborn infants: Survey of the Italian society of pediatric surgery

2020

Abstract Introduction This is the report of the first official survey from the Italian Society of Pediatric Surgery (ISPS) to appraise the distribution and organization of bedside surgery in the neonatal intensive care units (NICU) in Italy. Methods A questionnaire requesting general data, staff data and workload data of the centers was developed and sent by means of an online cloud-based software instrument to all Italian pediatric surgery Units. Results The survey was answered by 34 (65%) out of 52 centers. NICU bedside surgery is reported in 81.8% of the pediatric surgery centers. A lower prevalence of bedside surgical practice in the NICU was reported for Southern Italy and the islands …

Neonatal intensive care unitmedicine.medical_treatmentPractice PatternsReviewBedside surgeryNeonatal intensive care unit Bedside surgery Operative room Intrahospital transport Critically ill neonates0302 clinical medicineInformed consentNeonatalSurveys and QuestionnairesPediatric surgeryPractice Patterns Physicians'Societies MedicalBedside surgery; Critically ill neonates; Intrahospital transport; Neonatal intensive care unit; Operative roomlcsh:RJ1-570Operative roomOperativeCritically ill neonatesIntensive Care UnitsPneumothoraxItaly030220 oncology & carcinogenesisSurgical Procedures OperativeCentral venous catheterInfant Prematuremedicine.medical_specialtyPerforation (oil well)Critically ill neonate03 medical and health sciencesNeonatal intensive care unitMedical030225 pediatricsIntensive careIntensive Care Units NeonatalmedicineHumansPrematureContraindicationPhysicians'Surgical Proceduresbusiness.industryBedside surgery Critically ill neonates Intrahospital transport Neonatal intensive care unit Operative room Humans; Infant Newborn Infant Premature Italy Practice Patterns Physicians' Societies Medical Surveys and Questionnaires Intensive Care Units Neonatal Surgical Procedures OperativeInfant NewbornInfantlcsh:PediatricsIntrahospital transportNewbornmedicine.diseaseSurgeryOperative room.Settore MED/20Societiesbusiness
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Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure : the DIANA study

2020

© 2020 The Author(s).

OriginalDELPHI METHODCritical Care and Intensive Care MedicineGUIDELINESlaw.invention0302 clinical medicineAnti-Infective Agents[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseaseslawEpidemiologyMedicine and Health SciencesAntimicrobial de-escalationEPIDEMIOLOGYComputingMilieux_MISCELLANEOUS[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseasesVentilator-associated pneumoniaIntensive care unitAnti-Bacterial Agents3. Good healthIntensive Care UnitsSTEWARDSHIP PROGRAM[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/VirologyCohortAntimicrobial de-escalation; Bacterial infection; Clinical cure; Empirical therapy; Intensive care unit;Clinical cureAntimicrobial de-escalation; Bacterial infection; Clinical cure; Empirical therapy; Intensive care unitAdultmedicine.medical_specialtyCombination therapyCritical IllnessANTIBIOTIC-THERAPYNO03 medical and health sciences[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemBETA-LACTAMInternal medicineSettore MED/41 - ANESTESIOLOGIAmedicineHumans[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyIntensive care unitVENTILATOR-ASSOCIATED PNEUMONIAbusiness.industrySEPTIC SHOCKR-PACKAGEbacterial infectionIntensive care unit.030208 emergency & critical care medicinemedicine.disease[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyEmpirical therapyDiscontinuationSEVERE SEPSISlnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]Carbapenems030228 respiratory systemRelative riskBacterial infectionbusinessDe-escalation
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An international perspective on hospitalized patients with viral community-acquired pneumonia

2019

Background Who should be tested for viruses in patients with community acquired pneumonia (CAP), prevalence and risk factors for viral CAP are still debated. We evaluated the frequency of viral testing, virus prevalence, risk factors and treatment coverage with oseltamivir in patients admitted for CAP. Methods Secondary analysis of GLIMP, an international, multicenter, point-prevalence study of hospitalized adults with CAP. Testing frequency, prevalence of viral CAP and treatment with oseltamivir were assessed among patients who underwent a viral swab. Univariate and multivariate analysis was used to evaluate risk factors. Results 553 (14.9%) patients with CAP underwent nasal swab. Viral CA…

PNEUMONIAMaleMultivariate analysisInternationalityPCV13 pneumococcal conjugate vaccineDatabases FactualHospitalized patientsmedicine.medical_treatmentvirusesCAD coronary artery diseaseTesting030204 cardiovascular system & hematologyMRSA methicillin resistant Staphylococcus aureusPneumònia adquirida a la comunitatRT-PCR reverse transcriptase polymerase chain reactionchemistry.chemical_compound0302 clinical medicineCommunity-acquired pneumoniaTaverne80 and overCommunity-Acquired InfectionViral030212 general & internal medicineProspective StudiesAged 80 and overRIDT rapid influenza diagnostic testCAP community-acquired pneumoniaRSV Respiratory Syncytial virusMiddle AgedICU intensive care unitCommunity-Acquired InfectionsHospitalizationNasal SwabInfectious diseasesFemaleViral swabHumanOseltamivirmedicine.medical_specialtyLogistic ModelCommunity-acquired pneumoniaViral pneumoniaCommunity acquired pneumonia; Influenza; Oseltamivir; Testing; Viral pneumonia; Viral swab; Aged; Aged 80 and over; Antiviral Agents; Community-Acquired Infections; Cross-Sectional Studies; Databases Factual; Female; Hospitalization; Humans; Influenza Human; Internationality; Logistic Models; Male; Medication Adherence; Middle Aged; Oseltamivir; Pneumonia Viral; Prospective StudiesPneumonia ViralAdmissionSettore MED/10 - Malattie Dell'Apparato RespiratorioInfluenzavirusAntiviral AgentsVirusArticleMedication AdherenceHMPV human MetapneumovirusDatabases03 medical and health sciencesLRTI lower respiratory tract infectionOseltamivirInternal medicineInfluenza HumanInternal MedicinemedicineInfluenza virusesHumansHIV Human Immunodeficiency virusPPSV23 pneumococcal polysaccharide vaccineIn patientFactualAgedMechanical ventilationAntiviral AgentCross-Sectional Studiebusiness.industryFEV1 forced expiratory volume in one secondGLIMP global initiative for methicillin-resistant Staphylococcus aureus pneumoniaESBL extended-spectrum beta-lactamasesPneumoniamedicine.diseaseInfluenzaCommunity acquired pneumoniaCI confidence intervalOR odds ratioCross-Sectional StudiesLogistic ModelschemistryCOPD chronic obstructive pulmonary diseasebusinessCommunity acquired pneumonia ; Influenza ; Oseltamivir ; Testing ; Viral pneumonia ; Viral swab
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Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis.

2020

Abstract Background Throughout the 5000-year history of China, more than 300 epidemics were recorded. Traditional Chinese herbal medicine (TCM) has been used effectively to combat each of these epidemics’ infections, and saved many lives. To date, there are hundreds of herbal TCM formulae developed for the purpose of prevention and treatment during epidemic infections. When COVID-19 ravaged the Wuhan district in China in early January 2020, without a deep understanding about the nature of COVID-19, patients admitted to the TCM Hospital in Wuhan were immediately treated with TCM and reported later with >90% efficacy. Approach We conducted conduct a systematic survey of various TCM herbal pre…

PTGS2 Prostaglandin-endoperoxide synthase 2BattleAIV avian influenza virusCoV coronavirusPharmaceutical ScienceiNOS nitric oxide synthaseViral infection0302 clinical medicinePA patchouli alcoholSARS Severe Acute Respiratory SyndromeSMD Sheganmahuang decoctionDrug DiscoveryPandemicIL InterleukinMedicine Chinese TraditionalALI acute lung injuriesmedia_commonCOVID-19 coronavirus disease 2019MXSG Ma xing shi gan decoction0303 health sciencesTNF tumor necrosis factorClinical Trials as TopicCCL2 CC chemokine ligand 2FM1 FM1 coronavirusICU intensive care unitc-AMP cyclic adenosine phosphateHIV human immunodeficiency virus030220 oncology & carcinogenesisCOX-2 cyclooxygenase-2Molecular MedicineHerbal preparationsMedicinal herbsAbbreviations: ACE2 angiotensin-converting enzyme IITCM traditional Chinese medicineHSV-1 herpes simplex virus 1CASP3 caspase 3medicine.medical_specialtyChinaCoronavirus disease 2019 (COVID-19)Systematic surveymedia_common.quotation_subjectJEV Japanese encephalitis virusNF-κB nuclear factor kappa B cellsAntiviral AgentsArticleWHO World Health Organization03 medical and health sciencesIEC-6 rat intestinal epithelial cell line 6SOD superoxide dismutaseCDC Center for Disease Control and PreventionmedicineAVP arginine vasopressinPGE2 prostaglandin E2HumansIntensive care medicineLH Lianhuaqingwen capsule030304 developmental biologyPharmacologyMedicinal herbMDA malondialdehydeGCGJ Gancao ganjiang decoctionNO nitric oxidePlants Medicinalbusiness.industrySARS-CoV-2COVID-19CXCL C-X-C- motif chemokineMDCK Madin-Darby Canine Kidney cellsTLR-4 Toll-like receptor-4COVID-19 Drug TreatmentComplementary and alternative medicineViral infectionLPS lipopolysaccharidesRSV respiratory syncytial virusQFPD Qingfeipaidu decoctionbusinessLung congestionECMO extracorporeal membrane oxygenationMAPK mitogen-activated protein kinasePhytotherapyDrugs Chinese HerbalPhytomedicine : international journal of phytotherapy and phytopharmacology
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