Search results for " Learning"
showing 10 items of 5299 documents
Acute effects of fluoxetine on inhibitory avoidance consolidation in male and female OF1 mice
2001
The effects of acute administration of fluoxetine on memory consolidation using an inhibitory avoidance task were investigated in male and female OF1 mice. Several doses of this antidepressant (5, 10, and 20 mg/kg) were intraperitoneally administered immediately after the training session. The test session was carried out four days later and response latencies were measured in both sessions. The results showed that the highest dose of fluoxetine significantly increased response latencies of inhibitory avoidance compared with the lowest dose and the control group. Sex differences in this task were observed, females showing a better performance. But the drug's effects were not sexually dimorp…
Machine learning of reverse transcription signatures of variegated polymerases allows mapping and discrimination of methylated purines in limited tra…
2020
AbstractReverse transcription (RT) of RNA templates containing RNA modifications leads to synthesis of cDNA containing information on the modification in the form of misincorporation, arrest, or nucleotide skipping events. A compilation of such events from multiple cDNAs represents an RT-signature that is typical for a given modification, but, as we show here, depends also on the reverse transcriptase enzyme. A comparison of 13 different enzymes revealed a range of RT-signatures, with individual enzymes exhibiting average arrest rates between 20 and 75%, as well as average misincorporation rates between 30 and 75% in the read-through cDNA. Using RT-signatures from individual enzymes to trai…
The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent
2015
The combination of Reverse Transcription (RT) and high-throughput sequencing has emerged as a powerful combination to detect modified nucleotides in RNA via analysis of either abortive RT-products or of the incorporation of mismatched dNTPs into cDNA. Here we simultaneously analyze both parameters in detail with respect to the occurrence of N-1-methyladenosine (m1A) in the template RNA. This naturally occurring modification is associated with structural effects, but it is also known as a mediator of antibiotic resistance in ribosomal RNA. In structural probing experiments with dimethylsulfate, m1A is routinely detected by RT-arrest. A specifically developed RNA-Seq protocol was tailored to …
Facial emotion recognition in children and adolescents with specific learning disorder
2020
(1) Background: Some recent studies suggest that children and adolescents with different neurodevelopmental disorders perform worse in emotions recognition through facial expressions (ER) compared with typically developing peers. This impairment is also described in children with Specific Learning Disorders (SLD), compromising their scholastic achievement, social functioning, and quality of life. The purpose of our study is to evaluate ER skills in children and adolescents with SLD compared to a control group without learning disorders, and correlate them with intelligence and executive functions. (2) Materials and Methods: Our work is a cross-sectional observational study. Sixty-three chil…
Lifelong education: dialogues between Brazil and Spain
2020
Este artículo presenta una aproximación al desarrollo reciente de la educación a lo largo de la vida en el marco de la educación de adultos, en los contextos de Brasil y España. Inicia con una reflexión sobre la concepción de justicia cognitiva, que amplía la noción de igualdad de oportunidades en la educación, estableciendo la conexión entre educación de personas adultas y Educación Superior. Plantea una hipotética interpretación contemporánea de Paulo Freire acerca de la situación actual de la educación a lo largo de la vida y como ese enfoque podría inspirar una agenda de trabajo internacional para las universidades de Brasil y España. Las consideraciones finales señalan las diferencias …
Project Method in Adult Education: Self-Experience Analysis
2015
<p><em>The </em><em>project methodhas swiftly gained ground in education and it has nowbecome integral to the education process offering new ways for modernizing the education environment.Implementing projects provides learning opportunities for all of the involved parties – students, teachers, school principals and parents. In this article the Author has analysed the characteristics of the project method and the differences between project-based adult learningand non-adult learning,and the impact ofglobalization on projects. Projects can be implemented not only in the scope of specific subjects or specific schools but also as cooperation projects among schools of di…
Adult Education in Art Galleries
2016
Since I began researching adult education in art galleries 20 years ago in Europe, I have noticed two conflicting trends. Contemporary art has become more extraverted and socially engaged, whilst lifelong learning, the discourse of neoliberalism that informs most policy, has become increasingly focused on providing learners with predefined competencies and pushed for ‘measurable’ results (e.g. Pedersen, 2014; Illeris, 2015).
Transformative Learning, Bildung and Biographical Research
2017
The objective of this chapter, as the title states, is to relate transformative learning and Bildung within the context of biographical research. If processes of Bildung are defined as changes of attitude towards the world and the self, which is a consensus of Bildungs-oriented biographical research in Germany, and if one agrees furthermore that transformative learning and Bildung go together with fundamental changes of the self or the identity, it is rather surprising to note that both discourses have hardly ever been related.
FACILITATING THE ADULT LEARNING PROCESSES IN SECOND CHANCE EDUCATION : WHAT DO THE LATVIAN ADULT LEARNERS AND THEIR EDUCATORS THINK ABOUT ?
2015
The paper aims at presenting the findings of the research on core competences of adult educators conducted in Latvia during the study "Identification and analysis of new challenges and solutions that have influence on engagement and reintegration of adults (18- 24 years) in lifelong learning" funded by ESF project "Support to research in educational field" (sub-activity 1.2.2.3.2.), No 011/0011/1DP/1.2.2.3.2/11/IPIA/VIAA/001. The adult educators and adult learners from the field of second chance education (evening shift schools) were involved in an online survey (2011-2012) using the research tool developed in the project “Qualified to Teach” − QF2TEACH. The main research results are analys…
Two sides of the same coin? A new instrument to assess body checking and avoidance behaviors in eating disorders
2017
Body checking (BC) and avoidance behaviors (BA) are the dominant behavioral features of body image disturbances (BID) that characterize most individuals with eating disorders (EDs). Whereas BC can be reliably assessed, a valid assessment tool for BA is lacking, preventing an adequate assessment of BID differences across different EDs (anorexia nervosa, AN; bulimia nervosa, BN; binge eating disorder, BED). A total of 310 women with EDs and 112 nonclinical controls completed measures of BC-, BA- and ED-related symptoms. BA did not differentiate between EDs, whereas BC did: it was highest in AN and BN, and lowest in BED. Multivariate analyses also discriminated AN from BN based on BC. Given th…