Search results for " Major"

showing 10 items of 361 documents

Requirements for Th1-dependent immunity against infection with Leishmania major

2004

Protective immunity against cutaneous leishmaniasis is dependent on the induction of Th1/Tc1 immune responses resulting in efficient parasite elimination. In this review, the mechanisms leading to protection are discussed with special focus on the role of Leishmania major-infected dendritic cells (DC) in induction of Th1-dependent immunity. Murine strain-dependent differences between DC derived from Leishmania-susceptible as compared to resistant mice are highlighted.

Cellular immunityImmunologyLeishmaniasis CutaneousBiologyMicrobiologyMiceImmune systemCutaneous leishmaniasisImmunitymedicineAnimalsHumansLeishmania majorLeishmania majorAntigen PresentationMice Inbred BALB CDendritic CellsDendritic cellTh1 Cellsbiochemical phenomena metabolism and nutritionbiology.organism_classificationmedicine.diseaseLeishmaniaMice Inbred C57BLInfectious DiseasesImmunologyInterleukin 12Microbes and Infection
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Sicilian bottled natural waters: Major and trace inorganic components

2013

Sixteen bottled waters of various Sicilian brands, 11 natural mineral waters and five normal drinking waters, were analyzed for major and trace inorganic components by ion chromatography (IC) and inductively coupled plasma-mass spectrometry (ICP-MS), respectively. The bottled waters represent a variety of water types with significantly different compositions in terms of salinity, major components and trace elements. Chemically, they range from Ca–HCO3 and Ca–SO4 to Na–HCO3 types. Total dissolved solids ranges from 54 to 433 mg/L, total hardness from 25 to 238 mg/L CaCO3, and measured Na content from 5.7 to 57 mg/L. According to total dissolved ions, all the bottled waters were classified as…

ChemistryIon chromatographyBottled waterMass spectrometryTotal dissolved solidsPollutionSettore GEO/08 - Geochimica E VulcanologiaSalinityNutrientGeochemistry and PetrologyEnvironmental chemistryEnvironmental ChemistryWater qualitybottled natural waters major and trace elements municipal watersChemical compositionApplied Geochemistry
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Minimization of childhood maltreatment is common and consequential: results from a large, multinational sample using the childhood trauma questionnai…

2016

Childhood maltreatment has diverse, lifelong impact on morbidity and mortality. The Childhood Trauma Questionnaire (CTQ) is one of the most commonly used scales to assess and quantify these experiences and their impact. Curiously, despite very widespread use of the CTQ, scores on its Minimization-Denial (MD) subscale-originally designed to assess a positive response bias-are rarely reported. Hence, little is known about this measure. If response biases are either common or consequential, current practices of ignoring the MD scale deserve revision. Therewith, we designed a study to investigate 3 aspects of minimization, as defined by the CTQ's MD scale: 1) its prevalence; 2) its latent struc…

Child abuseMaleResearch ValidityPsychometrics150Social Scienceslcsh:MedicineDenial PsychologicalCriminology600 Technik Medizin angewandte Wissenschaften::610 Medizin und GesundheitInfographicsPediatricsNational comorbidity survey; Adult psychiatric-disorders; Form CTQ-SF; Psychometric properties; Household dysfunction; German Version; Life stress; Abuse; Reliability; ValiditySHORT FORM0302 clinical medicineSociologySurveys and QuestionnairesMedicine and Health SciencesPsychologyPublic and Occupational HealthDenial (Psychology)Child AbuseGERMAN VERSIONChildlcsh:Sciencemedia_commonViolence ResearchPediatricPsychiatryMultidisciplinaryIncidence (epidemiology)Child HealthResearch AssessmentHOUSEHOLD DYSFUNCTIONDisorders of movement Donders Center for Medical Neuroscience [Radboudumc 3]SuicideMental HealthDenialADULT PSYCHIATRIC-DISORDERSScale (social sciences)RELIABILITYchild; childhood; Childhood Trauma Questionnaire; dependent variable; human; human tissue; major clinical study; mental patient; prevalence; scientist; validity; volunteerFemaleCrimeGraphsMedicine; PsychiatryResearch Articlemedicine.medical_specialtyComputer and Information SciencesPsychometricsGeneral Science & Technologymedia_common.quotation_subjectMEDLINEPsychological Stress610Sample (statistics)Research and Analysis MethodsPsykiatri03 medical and health sciencesDenialClinical ResearchMental Health and PsychiatryADVERSITYmedicineHumansVALIDITYPsychiatryABUSEPsychiatric Status Rating Scalesbusiness.industryData Visualizationlcsh:RCTQ treeBiology and Life Sciences030227 psychiatryHealth Care100 Philosophie und Psychologie::150 PsychologiePSYCHOMETRIC PROPERTIESCTQPsychologicallcsh:QHealth StatisticsMorbiditybusiness030217 neurology & neurosurgeryPLOS ONE
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Association between cingulum bundle structure and cognitive performance: an observational study in major depression.

2009

AbstractBackgroundMajor depression can be regarded as a systemic neurobehavioral disorder resulting from dysfunction of the limbic-cortical networks. The cingulum bundle represents a major association fiber tract of those networks. The aim of our study was to determine the association of brain structural tissue markers of the cingulum bundle and cognitive function in patients with major depression.MethodsRegion-of-interest-based analyses of the middle-anterior and middle-posterior cingulum bundle fractional anisotropy (FA) and mean diffusivity (MD) using color-coded diffusion-tensor imaging and neuropsychological assessment in 14 patients with major depression.ResultsFA of the middle-anteri…

Cingulate cortexMalemedicine.medical_specialtyObservationNeuropsychological Testsbehavioral disciplines and activitiesGyrus CinguliFunctional Laterality03 medical and health sciencesAssociation fiber0302 clinical medicinePhysical medicine and rehabilitationMemoryFractional anisotropymedicineHumansAttention030212 general & internal medicineEffects of sleep deprivation on cognitive performanceNeuropsychological assessmentDepression (differential diagnoses)Depressive Disorder Majormedicine.diagnostic_testCognitionMiddle Aged030227 psychiatryPsychiatry and Mental healthDiffusion Tensor ImagingAnisotropyFemalePsychologyNeuroscienceDiffusion MRIEuropean psychiatry : the journal of the Association of European Psychiatrists
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Constitució d'una comunitat social d'investigació amb persones majors des de la responsabilitat social universitària = Constitution of a Social Resea…

2012

Es presenta com s'ha constituït una comunitat social d'investigació (CSI) amb 48 persones majors institucionalitzades des de la responsabilitat social universitària (RSU) i des d'una perspectiva humanista. En aquesta CSI es va valorar el benestar psicològic de les persones institucionalitzades amb mètodes quantitatius i qualitatius, i amb una proposta d'investigació-acció participativa (IAP). S'inicia, així, un procés d'innovació epistemològica, amb escassos antecedents, a l'hora d'investigar i entendre el benestar de les persones majors. Aquesta primera experiència de la CSI aporta observacions sobre els canvis de les dimensions del benestar de Ryff durant el procés d'envelliment dins de l…

Comunitat social d'investigació responsabilitat social universitària persones majors. Social research community university social responsibility elderly people. Artículo:PSICOLOGÍA [UNESCO]UNESCO::PSICOLOGÍA
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Chernobyl exposure as stressor during pregnancy and behaviour in adolescent offspring.

2007

Objective: Research in animals has shown that exposure to stressors during pregnancy is associated with offspring behavioural disorders. We aimed to study the effect of in utero exposure to the Chernobyl disaster in 1986, and maternal anxiety presumably associated with that exposure, on behaviour disorder observed at age 14. Method: Exposed (n = 232) and non-exposed Finnish twins (n = 572) were compared. A semi-structured interview was used to assess lifetime symptoms of depression, generalized anxiety disorder, attention deficit hyperactivity disorder, conduct disorder and oppositional defiant disorder symptoms. Results: Adolescents who were exposed from the second trimester in pregnancy o…

Conduct DisorderMalePediatricsmedicine.medical_specialtyGeneralized anxiety disorderAdolescentOffspringSeverity of Illness IndexArticleDevelopmental psychologyLife Change Events03 medical and health sciences0302 clinical medicineprenatal exposure delayed effectsPregnancySeverity of illnessmedicineAttention deficit hyperactivity disorderHumansDepression (differential diagnoses)chernobyl nuclear accidentPregnancyDepressive Disorder MajorBrainmedicine.diseaseAnxiety Disorders030227 psychiatryDiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthFetal DiseasesChernobyl Nuclear AccidentConduct disorderAttention Deficit Disorder with HyperactivityadolescentPrenatal Exposure Delayed EffectsMajor depressive disorderAdult ChildrenFemalePsychology030217 neurology & neurosurgeryActa psychiatrica Scandinavica
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LA CONTRATTAZIONE COLLETTIVA NEGLI STATI UNITI DAL WAGNER ACT AI NOSTRI GIORNI

2016

LA CONTRATTAZIONE COLLETTIVA NEGLI STATI UNITI. DAL WAGNER ACT AI NOSTRI GIORNI. — Riassunto. Il presente lavoro analizza la legislazione statunitense in materia di contrattazione collettiva sin dall’emanazione del Wagner Act nel 1935. Al riguardo, vengono discusse le regole per il riconoscimento dei sindacati nei luoghi di lavoro e per la stipula degli accordi collettivi (principio di maggioranza e rappresentanza esclusiva, obbligo di negoziare secondo buona fede) e per la gestione del conflitto industriale (arbitrato e clausola di tregua): sulla scorta di un approccio storico-critico e dei leading case giurisprudenzialil’articolosottolineailcarattereprettamenteaziendaleeprivatisticodellere…

Contrattazione collettiva – U.S.A. – Wagner Act – principio di maggioranza e rappresentanza esclusiva – obbligo di negoziare secondo buona fede – arbitrato – Chrysler.Collective bargaining – U.S.A. – Wagner Act – majority rule and exclusive representation – duty to bargain in good faith – arbitration – worker centers – Chrysler.Settore IUS/07 - Diritto Del Lavoro
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Development and validation of two PCR tests for the detection of and differentiation between Anaplasma ovis and Anaplasma marginale

2012

Anaplasma ovis and Anaplasma marginale are tick-transmitted bacteria that cause anaplasmosis in domestic and wild animals. Recent results show that some domestic and wild animals and ticks are susceptible to both A. ovis and A. marginale, thus supporting the need to differentiate between these species in hosts and ticks diagnosed with Anaplasma infection. However, although anaplasmosis is one of the most common diseases of grazing animals worldwide, rapid and effective tests are not available for the detection of and discrimination between these 2 Anaplasma species. The objective of this research was to develop an easy and reliable method to identify and discriminate between the closely rel…

DNA BacterialVeterinary MedicineAnaplasmosisAnaplasmaSequence analysisMolecular Sequence DataMicrobiologySensitivity and SpecificityBacterial geneticslaw.inventionMajor surface protein 4Bacterial Proteinslawparasitic diseasesAnaplasma Diagnostics major surface protein 4 Polymerase Chain ReactionmedicineAnimalsAnaplasmaPathogenOvisDiagnosticsPolymerase chain reactionDNA PrimersBacteriological TechniquesbiologyAnaplasma ovisAnaplasma ovisSequence Analysis DNAbiology.organism_classificationmedicine.diseaseVirologyPolymerase chain reactionAnaplasma marginaleInfectious DiseasesMolecular Diagnostic TechniquesInsect ScienceParasitologyAnaplasmosis
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Adequate Training and Multidisciplinary Support May Assist Pediatricians in Properly Handling and Managing Gender Incongruence and Dysphoria.

2022

What we call “sexual identity” refers to the complex relationship between biological sex, gender identity and role, and sexual orientation.1 “Gender identity” means the unified and persistent perception of oneself as belonging to the male or the female gender or ambivalent. For many, gender identity coincides with sexual identity; traditional culture has long provided for the definition of only 2 genders, corresponding to the 2 biological sexes. The person with gender incongruence experiences a disharmony between biological aspects and gender identity, with the constant awareness that he or she belongs to the opposite gender and is imprisoned in a body that does not represent him or her. Ge…

Depressive Disorder MajorPediatrics Perinatology and Child HealthHumansPediatriciansGender DysphoriaROGD (Rapid-onset of gender dysphoria)Transgender PersonsThe Journal of pediatrics
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Antidepressant-associated mood-switching and transition from unipolar major depression to bipolar disorder: A review

2012

Compare reported rates of mood-shifts from major depression to mania/hypomania/mixed-states during antidepressant (AD)-treatment and rates of diagnostic change from major depressive disorder (MDD) to bipolar disorder (BPD).Searching computerized literature databases, followed by summary analyses.In 51 reports of patients diagnosed with MDD and treated with an AD, the overall risk of mood-switching was 8.18% (7837/95,786) within 2.39 ± 2.99 years of treatment, or 3.42 (95% CI: 3.34-3.50) %/year. Risk was 2.6 (CI: 2.5-2.8) times greater with/without AD-treatment by meta-analysis of 10 controlled trials. Risk increased with time up to 24 months of treatment, with no secular change (1968-2012).…

Depressive Disorder Majormedicine.medical_specialtyPediatricsBipolar Disordermedicine.diseaseRisk Assessmentbehavioral disciplines and activitiesAntidepressive AgentsPsychiatry and Mental healthClinical PsychologyTreatment OutcomeMoodHypomaniamental disordersmedicineHumansAntidepressantMajor depressive disorderBipolar disordermedicine.symptomPsychiatryPsychologyManiaDepression (differential diagnoses)Randomized Controlled Trials as TopicJournal of Affective Disorders
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