Search results for " Mass"
showing 8 items of 5048 documents
Obesity and survival in operable breast cancer patients treated with adjuvant anthracyclines and taxanes according to pathological subtypes: a pooled…
2013
Obesity is an unfavorable prognostic factor in breast cancer (BC) patients regardless of menopausal status and treatment received. However, the association between obesity and survival outcome by pathological subtype requires further clarification. METHODS: We performed a retrospective analysis including 5,683 operable BC patients enrolled in four randomized clinical trials (GEICAM/9906, GEICAM/9805, GEICAM/2003-02, and BCIRG 001) evaluating anthracyclines and taxanes as adjuvant treatments. Our primary aim was to assess the prognostic effect of body mass index (BMI) on disease recurrence, breast cancer mortality (BCM), and overall mortality (OM). A secondary aim was to detect differences o…
Exploration des enjeux de la demande sociale pour les SIC
2016
Les Sciences de l’Information et de la Communication constituent un terrain d’observation privilégié du débat épistémologique opposant la recherche dite fondamentale à la recherche dite appliquée. Cette opposition produit systématiquement un déclassement qualitatif de la seconde au profit de la première. Nous souhaitons ici discuter de la pertinence même du débat ainsi que de ce déclassement qui en est la conséquence. La question est alors double : nos travaux s’inscrivent-il dans la recherche dite « appliquée » ? Sont-ils en cela moins valables scientifiquement que des recherches pouvant apparaître plus nobles car déconnectées d’une valorisation socio-économique ? En complément des élément…
Etude en champ proche et champ lointain de surfaces métalliques : apport des microscopies à sonde locale à l'étude des étalons de masse
2005
Among the international system of units (SI) the kilogram is the only one which is still defined by a material artefact, the international prototype of the platinum iridium kilogram. The instability of mass standards is one of the major concerns of national metrology institutes and the subject of numerous studies. Interest in microscopic studies of surface quality of a mass has grown, as it is well known that surface roughness is a factor in determining the long-term stability of mass standards. This thesis is devoted to the study in near field and far field for determining the topography and roughness of metallic surfaces, in related with different institute, national and international met…
Oglekļa un slāpekļa izotopu attiecību pētījumi dažādas šķirnes ābolos
2018
Darbā ir veikta literatūras izpēte par izotopu attiecības masspektrometriju un tā pielietojumiem dažādu augļu izcelsmes noteikšanai. Tika analizēts paraugu sagatavošanas process, kā arī izmantotās analīzes metodes. Pēc tam tika izstrādāta paraugu sagatavošanas metode un ar izotopu attiecības masspektrometru tika analizēti āboli no dažādām valstīm un iegūtie rezultāti savā starpā salīdzināti.
Profiling Dopamine-Induced Oxidized Proteoforms of β-synuclein by Top-Down Mass Spectrometry
2021
The formation of multiple proteoforms by post-translational modifications (PTMs) enables a single protein to acquire distinct functional roles in its biological context. Oxidation of methionine residues (Met) is a common PTM, involved in physiological (e.g., signaling) and pathological (e.g., oxidative stress) states. This PTM typically maps at multiple protein sites, generating a heterogeneous population of proteoforms with specific biophysical and biochemical properties. The identification and quantitation of the variety of oxidized proteoforms originated under a given condition is required to assess the exact molecular nature of the species responsible for the process under investigation…
High-precision measurement of a low Q value for allowed β−-decay of 131I related to neutrino mass determination
2022
The ground-state-to-ground-state β−-decay 131I (7/2+) → 131Xe (3/2+) Q value was determined with high precision utilizing the double Penning trap mass spectrometer JYFLTRAP at the IGISOL facility. The Q value of this β−-decay was found to be Q = 972.25(19) keV through a cyclotron frequency ratio measurement with a relative precision of 1.6 × 10−9. This was realized using the phase-imaging ion-cyclotron-resonance technique. The new Q value is more than 3 times more precise and 2.3σ higher (1.45 keV) than the value extracted from the Atomic Mass Evaluation 2020. Our measurement confirms that the β−-decay to the 9/2+ excited state at 971.22(13) keV in 131Xe is energetically allowed with a Q va…
The Use of Stable Isotope Ratio Analysis to Trace European Sea Bass (D. labrax) Originating from Different Farming Systems
2020
This study aimed to determine whether isotopic ratio mass spectrometry (IRMS) can discriminate farmed European sea bass according to different farming systems and geographic origins. Dicentrarchus labrax of commercial size from three different rearing systems (concrete tank inland, sea cages, and extensive methods in valleys or salt works) were collected at the trading period (autumn&ndash
Search for the Decay of the Higgs Boson to Charm Quarks with the ATLAS Experiment
2018
A direct search for the standard model Higgs boson decaying to a pair of charm quarks is presented. Associated production of the Higgs and Z bosons, in the decay mode ZH→ℓ+ℓ−c¯c is studied. A data set with an integrated luminosity of 36.1 fb−1 of pp collisions at √s=13TeV recorded by the ATLAS experiment at the LHC is used. The H→c¯c signature is identified using charm-tagging algorithms. The observed (expected) upper limit on σ(pp→ZH)×B(H→c¯c) is 2.7 (3.9+2.1−1.1) pb at the 95% confidence level for a Higgs boson mass of 125 GeV, while the standard model value is 26 fb.