Search results for " Medicinal"
showing 10 items of 590 documents
Polyacanthoside A, a new oleanane-type triterpenoid saponin with cytotoxic effects from the leaves of Acacia polyacantha (Fabaceae)
2018
The chemical investigation of the leaves and stem bark of Acacia polyacantha (Fabaceae) led to the isolation of a new oleanane-type triterpenoid saponin named polyacanthoside A 1 together with fifteen known compounds. Their structures were established from spectral , mainly HRESIMS, 1D NMR and 2D NMR and by comparison with literature data. The cytotoxicity of compound 1 and the analogues 8 as well as doxorubicin was determined in a panel of 9 cancer cell lines including sensitive and drug resistant phenotypes. Unlike the analogue 8, compound 1 as well as doxorubicin displayed cytotoxic effects in all the 9 tested cancer cell lines with IC50 values ranged from 8.90 μM (towards CCRF-CEM leuke…
Phytochemical analysis of two Weigela florida cultivars, “Pink Poppet” and “Jean’s Gold”
2020
Abstract Nine different oleanane-type glycosides were extracted and isolated by various chromatographic methods from two Weigela florida cultivars, “Pink Poppet” and “Jean’s Gold”. From the roots of W. florida “Pink Poppet”, three monodesmosidic oleanolic acid saponins 1, 4, 5 were obtained, together with one hederagenin ester 6 from the leaves, and six bidesmosidic saponins 2, 3, 6-9 were isolated from the leaves of W. florida “Jean’s Gold”. Among compounds 1-9, three were previously undescribed (1-3) and six (4-9) were already published in the literature. Their structures were assigned by spectroscopic analysis mainly 2D NMR and mass spectrometry (ESI-MS). The cytotoxicity of the isolated…
Phytochemical constituents and chemosystematic significance of Pulicaria jaubertii E.Gamal-Eldin (Asteraceae)
2018
Abstract The chemical characterization of methylene chloride/methanol (1:1) extract of the air-dried whole medicinal plant, Pulicaria jaubertii E. Gamal-Eldin, led to isolation and identification of two new hydroquinone compounds; 2-(2-acetoxy propyl), 5-methyl hydroquinone (1) and 2-(2-hydroxy propyl), 5-methyl hydroquinone-4-O-β-D-glucopyranoside (2), four known flavonols (3-6) and 7 known dihydroflavonols (7-13). The structures were established depending upon comprehensive analysis of the NMR, IR and HR/EI-MS data. Herein, compounds 6, and 10-13 were isolated for the first time from this plant. The chemotaxonomic significance of the isolated flavonoids from P. jaubertii comparing with th…
Saponin with antibacterial activity from the roots of Albizia adianthifolia
2019
AbstractAn unprecedented saponin is being reported herein together with five known compounds from the methanol extract of the roots of Albizia adianthifolia. The metabolites were obtained over repe...
(+)-(E)-Chrysanthenyl Acetate: A Molecule with Interesting Biological Properties Contained in the Anthemis secundiramea (Asteraceae) Flowers
2020
Anthemis secundiramea is a perennial herb native widespread throughout the Mediterranean basin. The oil obtained from the flowers of this plant has antimicrobial properties against gram-positive and -negative bacteria, and inhibits the biofilm formation. The extract of A. secundiramea also has antioxidant activity&mdash
Psychological Profile in Female Cyclists and Its Relationship with Age, Training Parameters, Sport Performance, and Injury Incidence.
2021
Previous studies have highlighted the importance of psychology on sports performance and its relationship with the incidence of sport injuries. The objectives of the present investigation were: (1) to analyze the psychological profile of female cyclists as a function of age, training parameters, sport performance, and injuries suffered and (2) to design a model to predict their psychological profile. Sixty-one female cyclists participated in the study. Differences were found as a function of a competitive category for team cohesion (F = 5.035
Genetic differentiation and structure of Hippocrepis valentina (Leguminosae) populations
2000
We present an analysis of isozyme variability in natural populations of the plant species Hippocrepis valentina (Leguminosae), which is endemic to the eastern Mediterranean coast of Spain and currently has endangered species status. Our results, obtained by starch-gel electrophoresis of 15 loci, show normal levels of variability for species with similar biology. The comparison with the patterns of genetic variability of two closely related species, H. balearica and H. grosii, confirms the taxonomic status of H. valentina as a proper species, independent of H. balearica, as previously suggested. The analysis of population subdivision shows that substantial variation among populations is pres…
Hairy Garlic (Allium subhirsutum) from Sicily (Italy): LC-DAD-MSn Analysis of Secondary Metabolites and In Vitro Biological Properties
2020
Allium subhirsutum, known as hairy garlic, is a bulbous plant widespread in the Mediterranean area and locally used as a food and spice. In the present study, the chemical profile of the ethanolic extracts from bulbs (BE) and aerial parts (APE) were analyzed by HPLC-ESI-MSn, and antioxidant properties were evaluated by DPPH, ABTS and TEAC assays. The traditional use in the diet, and the well documented biological activity of Allium species suggest a potential as a new nutraceutical. For this reason, the potential usefulness of this food can be considered in the treatment and prevention of degenerative Alzheimer disease. For this reason, acetylcholinesterase inhibitory property was investiga…
Exercicis de Farmacognòsia
2019
El present document ha rebut una subvenció atorgada pel Servei de Política Lingüística de la Universitat de València, en el marc de la convocatòria anual d'incentius per a materials docents en valencià i anglés. Els exercicis proposats inclouen aspectes relatius als metabòlits secundaris de plantes medicinals. Es tracta de resoldre una sèrie de qüestions sobre estructura química, biosíntesi, extracció, separació, identificació i activitat farmacològica de productes naturals d'origen biològic, fonamentalment vegetal. La major part dels exercicis s'han seleccionat a partir de publicacions en revistes de la màxima qualificació dins de l'àrea científica, sempre tenint en compte la plena adequac…
Cytotoxicity of 91 Kenyan indigenous medicinal plants towards human CCRF-CEM leukemia cells.
2015
Abstract Ethnopharmacological relevance Plants from Kenyan flora are traditionally used against many ailments, including cancer and related diseases. Cancer is characterized as a condition with complex signs and symptoms. Recently there are recommendations that ethnopharmacological usages such as immune and skin disorders, inflammatory, infectious, parasitic and viral diseases should be taken into account when selecting plants that treat cancer. Aim The present study was aimed at investigating the cytotoxicity of a plethora of 145 plant parts from 91 medicinal plants, most of which are used in the management of cancer and related diseases by different communities in Kenya, against CCRF-CEM …