Search results for " Moda"

Effect of hyperthermia on tumor blood flow.

1984

Differences in blood perfusion rates between tumors and normal tissue can be utilized to selectively heat many solid tumors. Blood flow in normal tissues is considerably increased at temperatures commonly applied during localized hyperthermia. In contrast, tumor blood flow may respond to localized heat typically in two different blood flow patterns: Flow may either decrease continuously with increasing exposure time and/or temperature or flow may exhibit a transient increase followed by a decline. A decrease in blood flow at high thermal doses can be observed in most of the tumors, whereas an increase in flow at low thermal doses seems to occur less frequently. The inhibition of blood flow …

Long-term resource utilisation and associated costs of exercise during (neo)adjuvant oncological treatment: the Phys-Can project

2022

Background Exercise during oncological treatment is beneficial to patient health and can counteract the side effects of treatment. Knowledge of the societal costs associated with an exercise intervention, however, is limited. The aims of the present study were to evaluate the long-term resource utilisation and societal costs of an exercise intervention conducted during (neo)adjuvant oncological treatment in a randomised control trial (RCT) versus usual care (UC), and to compare high-intensity (HI) versus low-to-moderate intensity (LMI) exercise in the RCT. Methods We used data from the Physical Training and Cancer (Phys-Can) project. In the RCT, 577 participants were randomised to HI or to …

L’IDENTIFICAZIONE DINAMICA DELLE CARATTERISTICHE MODALI E MECCANICHE DELLA STRUTTURA DELLA CUPOLA DEL TEATRO MASSIMO

2011

A Magnetic Resonance Imaging–Based Prediction Model for Prostate Biopsy Risk Stratification

2018

IMPORTANCE: Multiparametric magnetic resonance imaging (MRI) in conjunction with MRI–transrectal ultrasound (TRUS) fusion-guided biopsies have improved the detection of prostate cancer. It is unclear whether MRI itself adds additional value to multivariable prediction models based on clinical parameters. OBJECTIVE: To determine whether an MRI-based prediction model can reduce unnecessary biopsies in patients with suspected prostate cancer. DESIGN, SETTING, AND PARTICIPANTS: Patients underwent MRI, MRI-TRUS fusion-guided biopsy, and 12-core systematic biopsy in 1 session. The development cohort used to derive the prediction model consisted of 400 patients from 1 institution enrolled between …

Acetic acid compared with i-scan imaging for detecting Barrett's esophagus: a randomized, comparative trial.

2013

Background Traditional surveillance in patients with Barrett's esophagus (BE) has relied on random biopsies. Targeted biopsies that use advanced imaging modalities may significantly improve detection of specialized columnar epithelium (SCE). Objective We compared the efficacy of targeted biopsies that used i -scan or acetic acid to random biopsies in the detection of SCE. Design Patients with visible columnar lined epithelium or known BE were randomized at a 1:1 ratio to undergo acetic acid application or i -scan with targeted biopsies. Setting Targeted biopsies were performed based on surface architecture according to the Guelrud classification followed by 4-quadrant biopsies. Patients A t…

Reproduction beyond cancer: A message of hope for young women

2006

Abstract Objective. Aggressive chemotherapy and radiotherapy or radical oncological surgery in young women with cancer has greatly enhanced these patients' life expectancy, but these treatments often cause infertility or premature ovarian failure due to a massive destruction of the ovarian reserve. The objective of this review is to discuss the effect of the various cancer treatments on fertility and present the various fertility sparing operations and fertility preservation strategies. Method. An extensive survey of the most up-to-date literature was performed. Results. This review discusses the impact of current cancer treatment on fertility potential and the various surgical and assisted…

Congenital Müllerian anomalies: a review of currently available imaging modalities

2002

Congenital uterine anomalies are associated with infertility and adverse obstetric outcomes. The sensitivity of transvaginal sonography in diagnosing these anomalies ranges from 42% to 87%. More re...

The keyboard as a part of visual, auditory and kinesthetic processing in sight-reading at the piano

2009

Sight-reading at the piano requires coordination of multiple modalities—visual, auditory, and kinesthetic. Visual feedback (obtained by looking at the keyboard and the fingers) is usually regarded as one means by which pianists guide musical performance, but few researchers have focused on the organisational aspects implicit in the information provided by the keyboard. This study investigated the role of the keyboard with respect to the visual, auditory, and kinesthetic modalities involved in sight-reading. Five pianists sight-read two compositions, each in a different musical style. They were then interviewed in a semi-structured interview format. A qualitative content analysis was made fr…

REALIZATION OF INTEGRATED LEARNING IN STUDY PRACTICE: PRE-SERVICE TEACHERS EXPERIENCES

2018

The integrated teaching is important tool for promoting the development of students’ critical and creative thinking, self-cognition, learning and cooperation skills and cultural understanding in a constantly changing world. In Latvia, integrated curriculum has become a challenge for educational reforms, too. Latvian teacher educators are looking for appropriate Curriculum content and strategies, in order to promote pre-service teachers with understanding of integrated learning, courage and ability to implement them in professional activities. The aim of an article is analyze possibilities how to improve the pre-service teachers’ readiness to plan integrated lessons for study practice. Metho…

The addition of interleukin-2 to cyclophosphamide therapy can facilitate tumor growth of B16 melanoma.

1995

The role of interleukin-2 (IL-2) on tumor growth of B16F10 melanoma cells was assessed in two sets of mice with different immune status: normal (immunocompetent) mice and immunodeficient mice. The two sets of animals were treated with cyclophosphamide (CY) or IL-2 alone or with a combined therapy of CY+IL-2. On days 6 and 10 after tumor cell injection, we evaluated the incidence of hepatic B16 melanoma metastases and the percentage of hepatic volume occupied by metastatic tissue. We observed that the CY alone (300 mg/kg, days 3 and 8 post-tumoral inoculation) significantly reduced tumor growth in all treated mice; however, CY proved more effective in normal recipients than in immunodeficien…