Search results for " Movement"

Discovery of novel anti-inflammatory drug-like compounds by aligning in silico and in vivo screening: The nitroindazolinone chemotype

2011

In this report, we propose the combination of computational methods and in vivo primary screening in zebrafish larvae and confirmatory in mice models as a novel strategy to accelerate anti-inflammatory drug discovery. Initially, a database of 1213 organic chemicals with great structural variability - 587 of them anti-inflammatory agents plus 626 compounds with other clinical uses - was divided into training and test groups. Atom-based quadratic indices - a TOMOCOMD-CARDD molecular descriptors family - and linear discriminant analysis (LDA) were used to develop a total of 13 models to describe the anti-inflammatory activity. The best model (Eq. (13)) shows an accuracy of 87.70% in the traini…

Libre circulation des travailleurs dans l'Union Européenne et tutelle des droits individuels de retraite complémentaire: un chantier inachevé

2013

Freedom of movement of workers within the EU implies adequate regulation of risks incurred by workers on the occasion of the exercise of this freedom. Among these risks, there is the possibility for community workers to lose or at least find themselves unable to give their supplementary retirement pension individual rights an unitary and continuous character when they decide to settle in another member State. What are the legislative solutions already proposed by the Community legislature and even those expected by community workers to be protected from these dangers? Provide a draft answer to this question is the main concern of this work.

Pedagogia Nowego Człowieka ks. Franciszka Blachnickiego

2016

DEUTEROKATECHUMENALNA KATECHEZA MŁODZIEŻY W UJĘCIU SŁUGI BOŻEGO KS. FRANCISZKA BLACHNICKIEGO

2022

Artykuł jest próbą ukazania deuterokatechumenalnej koncepcji katechezy młodzieżowej w ujęciu sługi Bożego ks. Franciszka Blachnickiego. Ta oryginalna i rodzima propozycja kerygmatycznej odnowy katechezy jest cennym wkładem w rozwój pedagogiki katolickiej w Polsce. Ze względu na ścisły związek z ideałami soborowej deklaracji o wychowaniu chrześcijańskim, jednocześnie realizuje dzieło inicjacji, wychowania i nauczania, a skupiając się na spotkaniu z Bogiem i człowiekiem w Biblii i sakramentach Kościoła, jest głęboko związana z parafią i jej życiem liturgicznym. Posiada wszystkie cechy pojęcia rozumianego jako systemowe uporządkowanie poznania rzeczywistości edukacyjnej, czyli nieustannej peda…

2016

The neural systems supporting speech and sign processing are very similar, although not identical. In a previous fTCD study of hearing native signers (Gutierrez-Sigut, Daws, et al., 2015) we found stronger left lateralization for sign than speech. Given that this increased lateralization could not be explained by hand movement alone, the contribution of motor movement versus ‘linguistic’ processes to the strength of hemispheric lateralization during sign production remains unclear. Here we directly contrast lateralization strength of covert versus overt signing during phonological and semantic fluency tasks. To address the possibility that hearing native signers’ elevated lateralization ind…

Breaking down the word length effect on readers’ eye movements

2015

Previous research on the effect of word length on reading confounded the number of letters (NrL) in a word with its spatial width. Consequently, the extent to which visuospatial and attentional-linguistic processes contribute to the word length effect on parafoveal and foveal vision in reading and dyslexia is unknown. Scholars recently suggested that visual crowding is an important factor for determining an individual’s reading speed in fluent and dyslexic reading. We studied whether the NrL or the spatial width of target words affects fixation duration and saccadic measures in natural reading in fluent and dysfluent readers of a transparent orthography. Participants read natural sentences …

Eye tracking and the translation process: reflections on the analysis and interpretation of eye-tracking data

2014

Eye tracking has become increasingly popular as a quantitative research method in translation research. This paper discusses some of the major methodological issues involved in the use of eye tracking in translation research. It focuses specifically on challenges in the analysis and interpretation of eye-tracking data as reflections of cognitive processes during translation. Four types of methodological issues are discussed in the paper. The first part discusses the preparatory steps that precede the actual recording of eye-tracking data. The second part examines critically the general assumptions linking eye movements to cognitive processing in the context of translation research. The thir…

On-line assessment of comprehension processes

2009

In this paper we describe a new version of a former paper-and-pencil standardized comprehension test called Test of Comprehension Processes (Vidal-Abarca, Gilabert, Martínez, & Sellés, 2007). The new version has been adapted to a computer-based environment based on the moving window technique. It can be used to assess comprehension strategies of students from fifth to tenth grades (11 to 16 years old). Comprehension strategies are registered on-line using reading times and visits to relevant sections of the text during the question-answering process. Data show that the computerbased version draws similar results to those provided by the paper-and-pencil version. In addition, we identify the…

Can parafoveal-on-foveal effects be obtained when reading an unspaced alphasyllabic script (Thai)?

2013

One controversial question in the field of eye movements and reading is whether there is evidence of parafoveal-on-foveal effects. This is an important issue because some models of eye movements in reading make quite different predictions in this respect (e.g., E-Z Reader vs. SWIFT models). The aim of the current study was to investigate if parafoveal-on-foveal effects occur when reading Thai, an unspaced, alphasyllabic orthography. Word frequency (high and low) of the word to the right of the currently fixated word was manipulated to examine if it would influence processing of the fixated word. Thirty-six participants read single sentences while having their eye movements monitored. There …

Dual-stage and dual-deficit? Word recognition processes during text reading across the reading fluency continuum

2021

AbstractCentral questions in the study of visual word recognition and developmental dyslexia are whether early lexical activation precedes and supports decoding (a dual-stage view) or not (dual-route view), and the locus of deficits in dysfluent reading. The dual-route view predicts early word frequency and length interaction, whereas the dual-stage view predicts word frequency effect to precede the interaction effect. These predictions were tested on eye movements data collected from (n = 152) children aged 9–10 among whom reading dysfluency was overrepresented. In line with the dual-stage view, the results revealed an early word frequency effect in first fixation duration followed by robu…