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showing 10 items of 3606 documents

SAFETY PROBLEMS AND GLOBAL COMFORT IN RAILWAYS OPERATIONAL MANAGMENT

2008

In the planning process of a railway intervention and in its operational management, it needs to analyse carefully the relations between the different classes of variables constituting the complex system “vehicle-infrastructure-environment” to find the most suitable actions in optimisation the travelling comfort and safety, with respect for the ecosystem compatibilities. The problem can be tackled, in a systematic way, according to set theory and vector analysis, in a hyperspace Âd of d-dimension up to determining a characteristic global comfort vector that can be combined with each alternatives of intervention in the transport network examined. From this point of view, after the proper ach…

SAFETY RAILWAYS OPERATIONAL MANAGMENT
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Vasoactive peptide urotensin II in plasma is associated with cerebral vasospasm after aneurysmal subarachnoid hemorrhage and constitutes a potential …

2019

National audience; OBJECTIVECerebral vasospasm (VS) is a severe complication of aneurysmal subarachnoid hemorrhage (SAH). Urotensin II (UII) is a potent vasoactive peptide activating the urotensin (UT) receptor, potentially involved in brain vascular pathologies. The authors hypothesized that UII/UT system antagonism with the UT receptor antagonist/biased ligand urantide may be associated with post-SAH VS. The objectives of this study were 2-fold: 1) to leverage an experimental mouse model of SAH with VS in order to study the effect of urotensinergic system antagonism on neurological outcome, and 2) to investigate the association between plasma UII level and symptomatic VS after SAH in huma…

SAPS II = Simplified Acute Physiology Score IIMCA = middle cerebral arteryAUC = area under the curvesubarachnoid hemorrhage[SDV]Life Sciences [q-bio]ICU = intensive care unitUT = urotensin (receptor)vascular disordersintensive care unitUII = urotensin IIcardiovascular diseaseshumanmouseWFNS = World Federation of Neurosurgical SocietiesEVD = external ventricular drainageACA = anterior cerebral arteryurotensin IInervous system diseasesSAH = subarachnoid hemorrhageSE = standard errorROC = receiver operating characteristic[SDV] Life Sciences [q-bio]cerebral vasospasmVS = vasospasmDCI = delayed cerebral ischemiaCSF = cerebrospinal fluidIRB = institutional review boardmRS = modified Rankin ScaleIQR = interquartile range
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Delaying surgery for patients with a previous SARS-CoV-2 infection

2020

With at least 28 elective million operations delayed during the first three months of the COVID-19 pandemic, the number of patients who will require surgery after a previous SARS-CoV-2 infection is likely to increase rapidly1. Operating on patients with an active perioperative SARS-CoV-2 infection is now known to carry a very high pulmonary complication and mortality rate2. Urgent information is needed to guide whether postponing surgery in patients with a previous SARS-CoV-2 infection leads to a clinical benefit, and the optimal length of delay.

SARS Virus Coronavirus Severe Acute Respiratory Syndrome cancersurgery pandemic infectionSettore MED/06 - Oncologia MedicaSettore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALECOVID-19. Global surgery.Settore MED/19 - Chirurgia PlasticaComorbidity030230 surgeryCovidCOVID-19 / epidemiologysurgery0302 clinical medicineNeoplasms / surgeryNeoplasmsCOVID-19; Comorbidity; Humans; Neoplasms; Surgical Procedures Operative; Pandemics; SARS-CoV-2; Time-to-TreatmentProspective cohort study610 Medicine & healthCOVID-19/epidemiologymedicine.diagnostic_testSurgery sars-cov-2 covid surg surgery pandemic infectionPulmonary ComplicationSARS cov 2Covid19Surgical Procedures Operative / methodsOperativesurgery; Sars-CoV-2Surgical Procedures OperativeSurgery sars-cov-2Neoplasms / epidemiologyCohort studyHumanmedicine.medical_specialtySciences du Vivant [q-bio]/Médecine humaine et pathologieNOTime-to-TreatmentThroat culture03 medical and health sciencesSettore MED/28 - Malattie OdontostomatologichemedicineResearch LetterHumansElective surgeryGeneralPandemicscovid surgSurgical ProceduresPandemicbusiness.industrySARS-CoV-2No key words availablePostoperative complicationCOVID-19Perioperativemedicine.diseaseSurgeryPneumoniaSettore MED/40 - GINECOLOGIA E OSTETRICIANeoplasmSurgical Procedures Operative/methodsSurgerybusinessNeoplasms/epidemiology[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance

2022

Background & Aims Serum microRNA (miRNA) levels are known to change in non-alcoholic fatty liver disease (NAFLD) and may serve as useful biomarkers. This study aimed to profile miRNAs comprehensively at all NAFLD stages. Methods We profiled 2,083 serum miRNAs in a discovery cohort (183 cases with NAFLD representing the complete NAFLD spectrum and 10 population controls). miRNA libraries generated by HTG EdgeSeq were sequenced by Illumina NextSeq. Selected serum miRNAs were profiled in 372 additional cases with NAFLD and 15 population controls by quantitative reverse transcriptase PCR. Results Levels of 275 miRNAs differed between cases and population controls. Fewer differences were seen wi…

SCORING SYSTEMCPM counts per millionAUROC area under the receiver operating characteristicRC799-869AST aspartate aminotransferaseMicroRNA; Non-alcoholic fatty liver disease; Biomarker; SequencingTGF-β transforming growth factor-betaGastroenterologySTEATOHEPATITISLiver disease0302 clinical medicineFibrosismiRNA microRNAlogFC log2 fold changeFIBROSISImmunology and AllergySequencing0303 health scienceseducation.field_of_studyNAS NAFLD activity scoremedicine.diagnostic_testFatty liverGastroenterologyGTEx Genotype-Tissue ExpressionMicroRNADiseases of the digestive system. Gastroenterology3. Good healthReal-time polymerase chain reactionBiomarker MicroRNA Non-alcoholic fatty liver disease SequencingLiver biopsyACIDBiomarker (medicine)030211 gastroenterology & hepatologyLife Sciences & BiomedicineResearch ArticleEXPRESSIONmedicine.medical_specialtyNAFLD non-alcoholic fatty liver diseaseNASH non-alcoholic steatohepatitisPopulationGastroenterology and HepatologySAF steatosis–activity–fibrosisVALIDATIONER endoplasmic reticulum03 medical and health sciencescDNA complementary DNAInternal medicineALT alanine aminotransferaseGastroenterologiInternal MedicinemedicineNAFL non-alcoholic fatty liverALGORITHMFIB-4 fibrosis-4education030304 developmental biologyPCA principal component analysisScience & TechnologyGastroenterology & HepatologyHepatologybusiness.industryBiomarkerFC fold changemedicine.diseaseBiomarker; MicroRNA; Non-alcoholic fatty liver disease; Sequencingdigestive system diseasesFLIP fatty liver inhibition of progressionCt cycle thresholdSteatosisqPCR quantitative PCRbusinessNon-alcoholic fatty liver disease
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On the stability of the localized single-valued extension property under commuting perturbations

2013

This article concerns the permanence of the single-valued extension property at a point under suitable perturbations. While this property is, in general, not preserved under sums and products of commuting operators, we obtain positive results in the case of commuting perturbations that are quasi-nilpotent, algebraic, or Riesz operators.

SVEP quesi-nilpotent operatorsProperty (philosophy)Settore MAT/05 - Analisi MatematicaApplied MathematicsGeneral MathematicsMathematical analysisExtension (predicate logic)Operator theoryStability (probability)MathematicsProceedings of the American Mathematical Society
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Diagonalization of indefinite saddle point forms

2020

We obtain sufficient conditions that ensure block diagonalization (by a direct rotation) of sign-indefinite symmetric sesquilinear forms as well as the associated operators that are semi-bounded neither from below nor from above. In the semi-bounded case, we refine the obtained results and, as an example, revisit the block Stokes operator from fluid dynamics.

Saddle pointMathematical analysisFluid dynamicsBlock (permutation group theory)Perturbation theory (quantum mechanics)Stokes operatorRotation (mathematics)Mathematics
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VALUTAZIONE DEL MONITORAGGIO microbiologico DELL'ARIA IN SALA operatoria NELL'AOUP.

2009

Sala Operatoria MONITORAGGIO microbiologico AOUP.Settore MED/42 - Igiene Generale E Applicata
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Valutazione della qualità della Sala Operatoria in funzione della prevenzione del rischio [Evaluation of operating theatre for the risk prevention]

2008

In this study we analyse factors that predispose to risk and we value the importance of quality and reliability into operating theatre. Patient safety result from ability to plan and manage organizations able to reduce probability of mistakes (Prevention) and to recover and contain their consequences (Protection). The principal motives of mistakes are: - deficiency of sharing procedures between different professional figures for risk prevention; - deficiency of an effective integration between professional figures in operating theatre; - deficiency of charitable precise run to guarantee the continuity of interventions on patient. A risk management program have to take care on this sentinel …

Sala operatoria prevenzione rischioSettore MED/42 - Igiene Generale E Applicata
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Determinazione della qualita’ dell’aria all’interno di sale operatorie mediante “naso elettronico”

2006

Sale operatorieSettore ING-IND/11 - Fisica Tecnica AmbientaleIndoor Air Qualitynaso elettronico
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Long-run operation of a reverse electrodialysis system fed with wastewaters.

2018

The performance of a Reverse ElectroDialysis (RED) system fed by unconventional wastewater solutions for long operational periods is analysed for the first time. The experimental campaign was divided in a series of five independent long-runs which combined real wastewater solutions with artificial solutions for at least 10 days. The time evolution of electrical variables, gross power output and net power output, considering also pumping losses, was monitored: power density values obtained during the long-runs are comparable to those found in literature with artificial feed solutions of similar salinity. The increase in pressure drops and the development of membrane fouling were the main det…

SalinityEnvironmental Engineering02 engineering and technology010501 environmental sciencesManagement Monitoring Policy and LawWastewaterWastewater reuse01 natural sciencesElectricityReversed electrodialysisReverse electrodialysiOsmotic powerPressureSalinity gradient powerWaste Management and DisposalIon exchange membrane0105 earth and related environmental sciencesFoulingMembrane foulingMembranes ArtificialFoulingGeneral MedicineElectrodialysis021001 nanoscience & nanotechnologyPulp and paper industryUnit operation6. Clean waterWastewaterEnvironmental scienceElectric power0210 nano-technologyJournal of environmental management
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