Search results for " Operative"
showing 10 items of 497 documents
Expression of p63, p53 and ki-67 in patients with cervical intraepithelial neoplasia
2017
Objective: Cervical intraepithelial neoplasia (CIN) is a dysplastic process in cervical squamous epithelium and carries a risk of progression to cervical cancer. The aim of this study was to compare expression of three biomarkers named p53, p63 and Ki-67 in patients with various grades of cervical intraepithelial neoplasia and in a control group. Material and Method: 58 patients were enrolled in the study. Each patient underwent a colposcopy-guided biopsy of the cervix. Immunostaining for markers (p53, p63 and Ki-67) was performed on tissue samples of normal cases (n=10), CIN I (n=20), CIN II (n=14), and CIN III (n=14). Results: Our study showed a significant increase of the expression of t…
Effects of Polyacrylic Acid Pre-Treatment on Bonded-Dentine Interfaces Created with a Modern Bioactive Resin-Modified Glass Ionomer Cement and Subjec…
2018
Objectives: Resin-modified glass ionomer cements (RMGIC) are considered excellent restorative materials with unique therapeutic and anti-cariogenic activity. However, concerns exist regarding the use of polyacrylic acid as a dentine conditioner as it may influence the bonding performance of RMGIC. The aim of this study was to evaluate the effect of different protocols for cycling mechanical stress on the bond durability and interfacial ultramorphology of a modern RMGIC applied to dentine pre-treated with/without polyacrylic acid conditioner (PAA). Methods: The RMGIC was applied onto human dentine specimens prepared with silicon-carbide (SiC) abrasive paper with or without the use of a PAA c…
Repeated kidney re-transplantation—the Eurotransplant experience: a retrospective multicenter outcome analysis
2020
Transplant international (2020). doi:10.1111/tri.13569
Daphne II - Ve.R.S.O project: a new protocol for the management of sexual assault victims
2012
Daphne II - Ve.R.S.O project: a new protocol for the management of sexual assault victims. Sexual assault is a worldwide problem that has not yet been sufficiently acknowledged, as confirmed by analyses and studies carried out at different levels and in different contexts. Internationally, different approaches are taken to the collection of forensic evi- dence and to the clinical and psychological treatment of alleged victims. Italian law n.96, 1996, foreseeing norms regarding rape and abuse, finally gave signifi- cant relevance to sex crimes. In 2004, the European Commission for Justice Internal Affairs and Social Politics promoted the Daphne II pro- gram to support victims of rape and abu…
Cirugia de revisión en la lumbociatica
1987
The author presents eleven personal cases in which it has been necessary a revrsion surgery of the previous intervention for lumbar disk hernia, in order to have relapsed symptoms after the free assymptomatic interval. The common finding at surgery was a membrane flavectomy with or without a disk hernia.
Graft-versus-host disease, an eight case report and literature review.
2006
Graft versus host disease (GVHD) is a common complication in bone marrow transplant (BMT) patients. It is characterized by systemic and oral cavity alterations. Depending on the timing of lesions, GVHD is classified as acute or chronic. Alterations in the oral cavity are lichenoid reticular lesions, erythema, ulcerations, and xerostomia. Sporadically, mucocele and pyogenic granulomas can be present. Aim: To describe GVHD oral manifestations in eight allogenic BMT patients, and discuss GVHD and drug-immunosuppresion associated lesions diagnosis and treatment. Study design: For a year, we examined the oral mucosa of eight consecutive allogenic BMT patients attending the Dermatology outpatient…
Additional file 4 of Co-administration of human MSC overexpressing HIF-1�� increases human CD34+ cell engraftment in vivo
2021
Additional file 4. Figure S3. Analysis of human hematopoietic engraftment in spleen. Human hematopoietic engraftment was evaluated by flow cytometry after xenotrasplantation in NOD/SCID mice. The percentage of human CD45+ cells (donor chimerism) was analyzed in total spleen samples 4 weeks after transplantation. Mice were transplanted intravenously with CD34+ cells alone or co-transplanted with MSC WT or HIF-MSC, that were administered in the right femur. Data are represented as mean of 8 experiments for mice transplanted with CD34+ cells alone, 13 experiments for mice co-transplanted with CD34+ cells and WT MSC and 15 experiments for mice transplanted with CD34+ cells and HIF-MSC. p:n.s me…
Establishing a New ECMO Referral Center Using an ICU-Based Approach: A Feasibility and Safety Study
2022
Background: A high-volume center with a multidisciplinary team is regarded as the optimal place for providing extracorporeal membrane oxygenation (ECMO). We hypothesize that an ECMO center can also be successfully created and subsequently developed entirely by intensivists in a mid-size mixed intensive care unit (ICU). Methods: A model was created for setting up a new ECMO referral center within the structure of an existing mixed ICU in a tertiary hospital. A retrospective analysis was carried out of the first 33 patients treated in the initial period of the center’s activity, from mid 2018 to the end of 2020. Results: An ECMO center was established and developed entirely based on the resou…
Hepatocyte transplantation, a step forward?
2019
Hepatocyte transplantation emerged a few decades ago as a possible strategy to overcome some of the limitations of liver transplantation, among them the availability of organ donors and the functional quality of grafts. Nowadays, allogenic cell transplantation is still to be confirmed as a viable therapeutic option for patients with hereditary metabolic liver diseases. Although we have now overseen 5 decades of basic and animal research in the field, the number of successfully treated patients remains low. Limitations in cell engraftment and selective proliferation of transplanted cells remain a constraint to the generalized use of this therapeutic approach.
Resonancia nuclear magnética en roturas del ligamento cruzado anterior : sensibilidad y concordancia con hallazgos artroscópicos
2018
To estimate the sensitivity of magnetic resonance imaging (MRI) as a diagnostic test in anterior cruciate ligament (ACL) injuries, as well as its correlation with arthroscopic findings. Methods. Retrospective analysis of 270 patients who underwent ACL reconstruction surgery in our health department between 2007 and 2017. ACL injuries were diagnosed by radiologists specialized in musculoskeletal pathology, while the correlation between radiological and arthroscopic findings was determined through statistical analysis. Results. The sensitivity of the MRI regarding diagnosis of ACL injuries was 88.5%. In addition, the correlation between radiologic and arthroscopic findings was 73.3%. In 71% o…