Search results for " PREVALENCE"

showing 10 items of 296 documents

Emergence of Aspergillus fumigatus azole resistance in azole-naïve patients with chronic obstructive pulmonary disease and their homes.

2017

Azole-resistant Aspergillus fumigatus (ARAF) has been reported in patients with chronic obstructive pulmonary disease (COPD) but has not been specifically assessed so far. Here, we evaluated ARAF prevalence in azole-naïve COPD patients and their homes, and assessed whether CYP51A mutations were similar in clinical and environmental reservoirs. Sixty respiratory samples from 41 COPD patients with acute exacerbation and environmental samples from 36 of these patient's homes were prospectively collected. A. fumigatus was detected in respiratory samples from 11 of 41 patients (27%) and in 15 of 36 domiciles (42%). Cyp51A sequencing and selection on itraconazole medium of clinical (n = 68) and e…

Drug Resistance Fungal -- genetics0301 basic medicineAzolesMaleAntifungal AgentsExacerbationMESH: Fungal Proteins/isolation & purification[SDV]Life Sciences [q-bio]Colony Count MicrobialAspergillus fumigatusMESH: Aspergillus fumigatus/drug effectsMESH: Cytochrome P-450 Enzyme System/drug effectsMESH: GenotypePulmonary Disease Chronic ObstructivedwellingCytochrome P-450 Enzyme SystemGenotypePulmonary Disease Chronic Obstructive -- microbiologyPrevalenceProspective Studieschemistry.chemical_classificationMESH: AgedCOPDAzole-resistanceMESH: Middle AgedbiologyMESH: Drug Resistance Fungal/geneticsMold environmental exposureSciences bio-médicales et agricolesMiddle Aged3. Good healthMESH: Pulmonary Disease Chronic Obstructive/microbiology*MESH: Housing[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyAir Pollution IndoorAcute DiseaseDisease ProgressionMESH: Acute DiseaseMESH: Cytochrome P-450 Enzyme System/isolation & purificationMESH: Disease ProgressionFemalemedicine.drugmedicine.medical_specialtyEnvironmental EngineeringGenotypeItraconazoleMESH: Fungal Proteins/drug effects030106 microbiologyAspergillus fumigatus -- drug effects -- genetics -- isolation & purificationMESH: Azoles/pharmacology*Fungal Proteins -- drug effects -- isolation & purificationchronic obstructive pulmonary diseaseMicrobiologyFungal Proteins03 medical and health sciencesazole resistanceMESH: Air Pollution Indoor/analysis*Drug Resistance FungalInternal medicinemedicineCOPDHumansMESH: Aspergillus fumigatus/geneticsDwellingMESH: Colony Count MicrobialMESH: PrevalenceAgedAspergillusMESH: HumansAspergillus fumigatusAzoles -- pharmacologyelectrostatic dust collectorPublic Health Environmental and Occupational Healthmold environmental exposureElectrostatic dust collectorBuilding and Constructionmedicine.diseasebiology.organism_classificationMESH: MaleMESH: Prospective StudieschemistryCytochrome P-450 Enzyme System -- drug effects -- isolation & purificationHousingAzoleARAFMESH: Aspergillus fumigatus/isolation & purification*Antifungal Agents -- pharmacologyMESH: Antifungal Agents/pharmacology*MESH: FemaleAir Pollution Indoor -- analysisIndoor air
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Lipid-lowering drug use in Italian primary care: effects of reimbursement criteria revision

2008

OBJECTIVE: To assess whether the prescribing pattern of lipid-lowering drugs (LLD) changed after reimbursement criteria revision in a general practice in southern Italy. METHODS: From the Caserta-1 Local Health Service database, 93 general practitioners (GPs) who had consistently sent data about their patients during the years 2003-2005 were recruited. Prevalence of use and incidence of new treatments were calculated for each year, stratified by three drug cohorts: statins, omega-3 fatty acids, and fibrates. Subanalyses by gender, age, and indication of use were performed. RESULTS: Overall, 1-year prevalence of LLD use increased from 2003 to 2004. After reimbursement criteria revision (Nove…

Drug Utilizationmedicine.medical_specialtyPediatricsStatinSettore MED/09 - Medicina Internamedicine.drug_classMEDLINEstatinsInternal medicineFatty Acids Omega-3EpidemiologyHumansMedicinePharmacology (medical)RosuvastatinLipid-lowering drug Statins Omega-3 fatty acids Prevalence of use General practiceClofibrateReimbursementUnsaturated fatty acidHypolipidemic AgentsPharmacologygeneral practiceprevalence of usePrimary Health Careomega-3 fatty acidsbusiness.industryIncidence (epidemiology)General Medicinelipid-lowering drugSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheDrug UtilizationItalyInsurance Health ReimbursementSettore BIO/14 - FarmacologiaHydroxymethylglutaryl-CoA Reductase Inhibitorslipid-lowering drug; statins; omega-3 fatty acids; prevalence of use; general practicebusinessmedicine.drug
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Estimaciones de incidencia y prevalencia de enfermedades de origen laboral en España

2008

ObjetivoEstimar el impacto de las enfermedades laborales en España en términos de incidencia y prevalencia, y compararlo con las notificaciones realmente efectuadas.DiseñoSe obtienen datos de incidencia y prevalencia procedentes de estudios llevados a cabo en España y en otros países y basados en investigaciones epidemiológicas, en sistemas de vigilancia centinela de enfermedades laborales y en encuestas a muestras representativas de trabajadores.ParticipantesLos datos de incidencia y prevalencia obtenidos en estos estudios se aplican al conjunto de la población ocupada en España en 2006.EmplazamientoEspaña, 2006.Mediciones principalesIncidencia y prevalencia de enfermedades y alteraciones …

Enfermedades laboralesMedicine(all)Incidencia y prevalencia de enfermedades laboralesIncidence and prevalence of occupational diseasesOccupational healthbusiness.industryOccupational diseasesMedicineSalud laboralGeneral MedicinebusinessFamily PracticeHumanitiesAtención Primaria
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Patogēno Escherichia coli sastopamības biežums bērniem ar un bez alerģijām, kā arī to saistība ar riska faktoriem

2018

Mērķis – noteikt patogēno Escherichia coli tipu sastopamības biežumu bērniem bez gastroenterīta un analizēt tās saistību ar alerģijām, kā arī pētīt patogēnās E. coli nēsāšanas riska faktorus. Metodes – pētījums veikts Bērnu Klīniskajā Universitātes slimnīcā “Gaiļezers”, alergologa konsultācijā, primārās aprūpes centros un bērnudārzos Rīgā un tās rajonā. Bērnu vecākiem tika lūgts aizpildīt aptaujas anketu, kā arī atnest bērna fēču paraugu. Molekulārbioloģiskajā laboratorijā ar PCR metodi no fēcēm tika izdalīts patogēno E. coli DNS, tā nosakot tās patogēnos tipus: enteropatogēno, enterotoksigēno, enteroagregatīvo, enterohemorāgisko un E. coli O157. Patogēno E. coli biežums tika salīdzināts bē…

Enterohemorāģiskā Escherichia coliAsimptomātiskas Escherichia coli prevalencePatogēnā Escherichia coliHigiēnas hipotēzeAlerģijas bērniem LatvijāMedicīna
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Fusaproliferin, beauvericin and enniatins: occurrence in food – a review

2012

The present review summarises data on the prevalence and concentration of fusaproliferin, beauvericin and enniatins in small grains, maize and processed grain-based foods. These fungal secondary metabolites possess interesting biological activities and are presently often referred to as 'emerging mycotoxins'. They have been considered as less important since they are likely not of acute toxicity. However, their high prevalence in foodstuffs, occasionally in higher mg/kg concentrations, warrants an assessment of their true importance for food (and feed) safety. Thorough surveys that determine the contamination of raw and processed foods with fusaproliferin, beauvericin and enniatins are sti…

FUMONISIN B-1MAIZE EAR ROTBiologyToxicologyToxicologychemistry.chemical_compoundHuman healthCRYSTAL-STRUCTUREFood scienceLC-MS/MSMycotoxinCARRY-OVERHigh prevalencebusiness.industryPublic Health Environmental and Occupational HealthFUSARIUM-MYCOTOXINS FUSAPROLIFERINMASS-SPECTROMETRYBeauvericinFusaproliferinARTEMIA-SALINAchemistryHEAD BLIGHTFood processingSECTION LISEOLAbusinessFood ScienceFood contaminantWorld Mycotoxin Journal
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Retrospective Analysis of Functional Pain among Professional Climbers

2022

Climbing became one of the official Olympic sports in 2020. The nociplastic pain mechanism is indicated as important in professional sports. Functional pain, which has not been examined in climbers until now, can be an example of nociplastic pain. This study aimed to determine functional pain locations in climbers according to gender and dominant climbing style. Climbers (n = 183) and healthy subjects (n = 160) completed an online survey focused on functional pain occurrence in the head, spine, and upper limbs. The logistic regression showed that climbing predisposes one to functional pain at: Gleno-humeral joint (odds ratio (OR): 3.06; area under the curve (AUC): 0.635), elbow (OR: 2.86; A…

Fluid Flow and Transfer ProcessesProcess Chemistry and Technologyboulderingclimbing; bouldering; athletes; functional pain; pain prevalence; upper limbGeneral Engineeringupper limbfunctional painComputer Science Applicationsathletespain prevalenceclimbingGeneral Materials Sciencehuman activitiesInstrumentationApplied Sciences
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Framing Social Work Discourses of Violence Against Women. Insights From Finland and India

2021

Violence against women (VAW) is a global social problem. In India, its high prevalence is connected to gender inequality, whereas Finland suffers from the so-called Nordic Paradox—that is, the existence of both gender equality and a high prevalence of VAW. This qualitative study employed a critical constructioniist approach and frame analysis to analyze data from interviews with Finnish (n =20) and Mumbai (n =18) social workers. We asked how social workers frame their response to VAW and how ways of framing elucidate institutional practices that facilitate the interventions. Anti-oppressive, juridical, procedural, and collaborational frames revealed institutional practices mirroring how soc…

Gender inequalityHigh prevalencedomestic violenceSocial workperheväkivaltaväkivaltasosiokulttuuriset tekijätGender studiesSocial issuessukupuolittuminensosiaalityöGender Studiesväkivaltatyö5142 Social policygender-based violencesocial work practiceFraming (construction)Suomi5141 SociologyIntiaDomestic violenceSociologySocial Sciences (miscellaneous)
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RISK OF CARDIOVASCULAR DISEASE MORBIDITY AND MORTALITY IN FRAIL AND PRE-FRAIL OLDER ADULTS:RESULTS FROM A META-ANALYSIS AND EXPLORATORY META-REGRESSI…

2017

Frailty is common and associated with poorer outcomes in the elderly, but its role as potential cardiovascular disease (CVD) risk factor requires clarification. We thus aimed to meta-analytically evaluate the evidence of frailty and pre-frailty as risk factors for CVD. Two reviewers selected all studies comparing data about CVD prevalence or incidence rates between frail/pre-frail vs. robust. The association between frailty status and CVD in cross-sectional studies was explored by calculating and pooling crude and adjusted odds ratios (ORs)+/- 95% confidence intervals (CIs); the data from longitudinal studies were pooled using the adjusted hazard ratios (HRs). Eighteen cohorts with a total …

GerontologyAging1303 Biochemistry030204 cardiovascular system & hematologyBiochemistry0302 clinical medicineRisk Factorscardiovascular diseasePrevalenceMedicine030212 general & internal medicineCardiovascular disease; Frailty; Meta-analysis; Aged; Frail Elderly; Humans; Prevalence; Risk Assessment; Risk Factors; Cardiovascular Diseases; Biotechnology; Biochemistry; Aging; Molecular Biology; NeurologyOXIDATIVE STRESSProspective cohort studyELDERLY-PATIENTSPOPULATIONeducation.field_of_studyFrailtyHazard ratioMENASSOCIATION16. Peace & justiceCardiovascular disease3. Good healthMIDLIFE OBESITYNeurologyCardiovascular DiseasesMeta-analysis1305 BiotechnologyRisk assessmentCardiovascular disease; Frailty; Meta-analysis; Aged; Frail Elderly; Humans; Prevalence; Risk Assessment; Risk Factors; Cardiovascular DiseasesBiotechnologymedicine.medical_specialtyWOMENS-HEALTHFrail ElderlyPopulationCardiovascular disease; Frailty; Meta-analysis; Biotechnology; Biochemistry; Aging; Molecular Biology; Neurology610 Medicine & healthfrailtyFrailty Cardiovascular disease Meta-analysisRisk AssessmentArticle03 medical and health sciences1302 AgingInternal medicine1312 Molecular BiologyHumansCORONARY-HEART-DISEASERisk factorFrailty cardiovascular disease meta-analysiseducationMolecular BiologyAgedbusiness.industryAGE FRAILTYOdds ratio10060 Epidemiology Biostatistics and Prevention Institute (EBPI)Confidence intervalmeta-analysisMeta-analysis3121 General medicine internal medicine and other clinical medicine2808 NeurologyFOLLOW-UPbusiness
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Prevalence of multidimensional frailty and pre-frailty in older people in different settings: A systematic review and meta-analysis.

2021

Frailty is a common condition in older people. The epidemiological data available, however, are mainly based on the physical frailty phenotype. An extensive literature has suggested that frailty should be identified using a multidimensional approach. Based on these recommendations, we estimated the prevalence of frailty and pre-frailty in the older population, using the multidimensional prognostic index (MPI), a common tool for defining multidimensional frailty. We searched several databases until 10th May 2021 for studies reporting the prevalence of frailty according to MPI values. MPI was categorized, where possible, in < 0.33 (robustness), 0.33–0.66 (pre-frailty) and > 0.66 (frailt…

GerontologyAgingmedicine.medical_specialtyHospital settingEpidemiologyFrail ElderlyPopulationComprehensive geriatric assessmentBiochemistryComprehensive geriatric assessment; Epidemiology; Frailty; Multidimensional prognostic index; Prevalence; Aged; Female; Frail Elderly; Geriatric Assessment; Humans; Prevalence; Prognosis; FrailtyPre frailtyMultidimensional prognostic indexEpidemiologymedicinePrevalenceHumanseducationMolecular BiologyGeriatric AssessmentAgededucation.field_of_studyFrailtybusiness.industryPrognosisConfidence intervalNeurologyMeta-analysisAmbulatoryFemaleOlder peoplebusinessBiotechnologyAgeing research reviews
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Agreement between different versions of MNA.

2013

Malnutrition occurs frequently in the elderly with important clinical and functional consequences. Moreover, the treatment of malnutrition in the elderly may be effective if clinical and nutritional interventions are performed in the early stages. Therefore the early identification of the risk of malnutrition using validated and handy tools plays a pivotal role in terms of clinical outcome. Mini Nutritional Assessment (MNA) was validated for this purpose since many years but it is still ongoing the debate over whether the use of different items in certain clinical conditions can be effective without affecting the validity of the nutritional status evaluation. The aim of this study was to as…

GerontologyMaleMini nutritional assessmentMEDLINEMedicine (miscellaneous)Nutritional StatuselderlyRisk AssessmentSensitivity and SpecificityBody Mass IndexNutritional InterventionsRisk FactorsSurveys and Questionnairesmedicine80 and overNutrition and DieteticPrevalenceSurveys and QuestionnaireHomes for the AgedHumanselderly; malnutrition; MNA; Aged; Aged 80 and over; Body Mass Index; Female; Geriatric Assessment; Humans; Italy; Male; Malnutrition; Nutritional Status; Prevalence; Risk Assessment; Risk Factors; Sensitivity and Specificity; Surveys and Questionnaires; Homes for the Aged; Nursing Homes; Nutrition Assessment; Medicine (miscellaneous); Nutrition and Dietetics; Geriatrics and GerontologyNutritional riskGeriatric AssessmentAgedAged 80 and overNutrition and Dieteticsbusiness.industryRisk FactorMalnutritionNutritional statusmedicine.diseaseNursing HomesMalnutritionNutritional StatuNursing HomeNutrition AssessmentMNAItalymna; elderly; malnutritionFemaleGeriatrics and GerontologybusinessRisk assessmentBody mass indexHumanThe journal of nutrition, healthaging
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