Search results for " Polyphenol"

showing 10 items of 128 documents

Effects of irrigation on fruit ripening behavior and metabolic changes in olive

2012

Olive (Olea europaea, cv Leccino) fruits grown under different water regimes were analyzed by metabolomics and specific transcript accumulation analyses. The fruit from non-irrigated (rain-fed) and irrigated trees cultivated under field conditions, with a seasonal water amount equivalent to the calculated crop evapotranspiration (ETc) was compared in the last developmental phase and, in particular, at commercial harvest. Metabolomics (GC-MS) analysis identified several hundred metabolites in ripe mesocarp, 46 of which showed significantly different contents in the rain-fed and irrigated samples. Some compounds involved in primary metabolism (carbohydrates, amino acids, organic acids) and se…

Chalcone synthasePhenylalanine ammonia-lyaseHorticultureBiologychemistry.chemical_compoundSettore AGR/07 - Genetica AgrariaBotanyMetabolomicsSecondary metabolismOlea europaeaIrrigationfood and beveragesPolyphenolsRipeningbiology.organism_classificationFruit ripeningdevelopmental stage enzyme activity evapotranspiration fruit gene expression hydrological regime irrigation system metabolism metabolite phenol physiological response phytochemistry pigment ripening terpeneFruit ripening Irrigation Metabolomics Olea europaea PolyphenolsHorticulturechemistryCycloartenol synthasePolyphenolOleaAnthocyaninbiology.proteinOlea europaea Oleaceae
researchProduct

Effetti dell’essiccamento sull’attività polifenolossidasica e pattern antiossidante di pomodoro ciliegino(Effects of drying process on polyphenol oxi…

2010

Cherry tomato dryng polyphenol oxidase antioxidant activity lycopene phenols ascorbic acid
researchProduct

Valorization of apple peels through the study of the effects on the amyloid aggregation process of ?-casein

2021

Waste valorization represents one of the main social challenges when promoting a circular economy and environmental sustainability. Here, we evaluated the effect of the polyphenols extracted from apple peels, normally disposed of as waste, on the amyloid aggregation process of ?-casein from bovine milk, a well-used amyloidogenic model system. The effect of the apple peel extract on protein aggregation was examined using a thioflavin T fluorescence assay, Congo red binding assay, circular dichroism, light scattering, and atomic force microscopy. We found that the phenolic extract from the peel of apples of the cultivar "Fuji", cultivated in Sicily (Caltavuturo, Italy), inhibited ?-casein fib…

Circular dichroismMalusAmyloidAmyloidSettore CHIM/10 - Chimica Degli Alimenti&#954INHIBITIONPharmaceutical ScienceOrganic chemistryPROTEINProtein aggregationMicroscopy Atomic ForceFIBRIL FORMATIONArticleAnalytical Chemistry03 medical and health scienceschemistry.chemical_compound0302 clinical medicineQD241-441OLIGOMERSCaseinTRANSTHYRETIN AMYLOIDOSISANTIOXIDANTDrug Discovery-casein amyloid aggregationFood sciencePhysical and Theoretical Chemistrypolyphenolic extract030304 developmental biology0303 health sciencesbiologyChemistryNATURAL POLYPHENOLSCaseinsκ-casein amyloid aggregationbiology.organism_classificationSTATECongo redfruit wasteChemistry (miscellaneous)PolyphenolFIBRILLOGENESISMalusFruit waste; Polyphenolic extract; ?-casein amyloid aggregationMolecular MedicineThioflavinTHIOFLAVIN-T030217 neurology & neurosurgery
researchProduct

Polyphenols from halophytes and modified atmosphere packaging improve sensorial and biochemical markers of quality of common dolphinfish (Coryphaena …

2016

Quality and shelf-life of whole and filleted Coryphaena hippurus, stored with modified atmosphere packaging (MAP) and natural antioxidants from halophytes (HAL), were investigated. Fillets were divided into control, simply sealed in trays; MAP, preserved by modified atmosphere (45% CO2, 50% N-2, 5% O-2); and MAP-HAL, pretreated with antioxidants and preserved by MAP. Whole and filleted fish were stored at -1 +/- 0.5 degrees C for 18days. The quality of the samples was analyzed at the time of packaging and after 3, 6, 9, 12, 15, and 18days. The MAP and MAP-HAL groups maintained the best sensorial profile, pH, and drip loss with respect to the untreated fillets. Higher levels of total volatil…

Coryphaenamodified atmosphere packagingbiologyChemistryFish modifid atmosphere packaging polyphenols shelf-life04 agricultural and veterinary sciencesbiology.organism_classificationShelf life040401 food scienceFish0404 agricultural biotechnologyTotal volatileSettore AGR/20 - ZoocolturePolyphenolHalophyteModified atmosphereFish <Actinopterygii>Food scienceshelf‐lifeSettore BIO/06 - Anatomia Comparata E CitologiapolyphenolsBiochemical markersOriginal ResearchFood ScienceFood Science &amp; Nutrition
researchProduct

Functional bread supplemented with Pleurotus eryngii powder: A potential new food for human health

2022

The purpose of this study was to develop functional breads with powdered Pleurotus eryngii. The breads were produced applying the traditional Italian style sourdough technology. P. eryngii powder was added to flour of tender wheat varieties (Grano Dei Miracoli, Inalettabile, Mentana, Gentilrosso, Ardito and a mix of Rieti, Verna, and Mentana) or semolina of durum wheat landrace (Saragolla) and subjected to sourdough fermentation. Sourdough inoculum was produced with selected strains of lactic acid bacteria (LAB) belonging to the species Levilactobacillus brevis, Weissella cibaria and Leuconostoc citreum. The addition of Pleurotus powdered (PP) (10% w/w) did not influence the fermentation pr…

Cultural StudiesSettore BIO/03 - Botanica Ambientale E ApplicataSourdough bread Pleurotus eryngii Functional foods Vitamins Beta-glucans PolyphenolsSettore AGR/16 - Microbiologia AgrariaFood ScienceInternational Journal of Gastronomy and Food Science
researchProduct

Multifactorial nature of hepatocellular carcinoma drug resistance: Could plant polyphenols be helpful?

2007

Primary hepatocellular carcinoma (HCC) is a quite frequent tumor which results in high mortality and most often exhibits a poor response to present drug therapies. Clearly, a thorough understanding of the biological bases of this malignancy might suggest new strategies for its treatment. Here we examine the evidences that both "pharmacological" mechanisms (e.g. drug transporter or detoxification enzyme over-expression) and alterations in other critical factors, including the IAPs (Inhibitory of Apoptosis Proteins), involved in enhancement of cell survival and proliferation may determine the therapeutic resistance of HCC; we also underline the possible role in the process of the activation o…

DrugCarcinoma HepatocellularHepatocellular carcinomamedia_common.quotation_subjectDrug transporterDrug resistancePharmacologyBiologyMalignancyNF-κBInhibitor of Apoptosis ProteinsPlant polyphenolsPhenolsmedicineHumansInhibition of cell deathTopic HighlightsTranscription factorSensitizationmedia_commonFlavonoidsLiver NeoplasmsNF-kappa BGastroenterologyPolyphenolsGeneral MedicineIAPmedicine.diseaseNFKB1medicine.anatomical_structureDrug Resistance NeoplasmApoptosisDrug resistanceHepatocellular carcinomaCancer researchPlant PreparationsPhytotherapyWorld Journal of Gastroenterology
researchProduct

Natural polyphenols in cancer therapy.

2011

Natural polyphenols are secondary metabolites of plants involved in defense against different types of stress. Extracts containing these compounds have been used for thousands of years in traditional eastern medicine. Polyphenols act on multiple targets in pathways and mechanisms related to carcinogenesis, tumor cell proliferation and death, inflammation, metastatic spread, angiogenesis, or drug and radiation resistance. Nevertheless, reported effects claimed for polyphenols are controversial, since correlations between in vitro effects and in vivo evidence are poorly established. The main discrepancy between health claims versus clinical observations is the frequent use of nonphysiological…

DrugLung NeoplasmsSkin Neoplasmsmedia_common.quotation_subjectClinical BiochemistryBiological AvailabilityResveratrolPharmacologymedicine.disease_causeGeneral Biochemistry Genetics and Molecular Biologychemistry.chemical_compoundIn vivoAnimals LaboratoryNeoplasmsToxicity TestsmedicineAnimalsHumansMelanomaBiotransformationmedia_commonPlants MedicinalMolecular Structurebusiness.industryPlant ExtractsBiochemistry (medical)food and beveragesCancerPolyphenolsmedicine.diseaseBioavailabilitychemistryPolyphenolHealth effects of natural phenols and polyphenolsMedicine TraditionalCarcinogenesisbusinessColorectal NeoplasmsCritical reviews in clinical laboratory sciences
researchProduct

Application of ultrasound as clean technology for extraction of specialized metabolites from stinging nettle (Urtica dioica L.)

2022

Nettle is a highly valued medicinal plant that is still largely neglected, both in terms of nutrition and use for pharmacological purposes. Tinctures, i.e., alcoholic extracts, are becoming increasingly popular nettle products, mainly because they allow better availability of phytochemicals and their stability over a longer period of time. The production of alcoholic extracts is a chemically demanding process that is still usually carried out using conventional techniques, which have numerous drawbacks. The use of green technologies such as ultrasound-assisted extraction (UAE), which is characterized by high efficiency of phytochemical extraction, shorter treatment time, and a much lower en…

FarmacologiaNutrition and DieteticsEndocrinology Diabetes and Metabolismultrasound-assisted extraction ; ethanolic extracts ; polyphenols ; ascorbic acid ; pigments ; antioxidant capacityPlantes medicinalsFood Science
researchProduct

Recovery of oil with unsaturated fatty acids and polyphenols from chaenomelessinensis (Thouin) Koehne: Process optimization of pilot-scale subcritica…

2017

The potential effects of three modern extraction technologies (cold-pressing, microwaves and subcritical fluids) on the recovery of oil from Chaenomelessinensis (Thouin) Koehne seeds have been evaluated and compared to those of conventional chemical extraction methods (Soxhlet extraction). This oil contains unsaturated fatty acids and polyphenols. Subcritical fluid extraction (SbFE) provided the highest yield—25.79 g oil/100 g dry seeds—of the three methods. Moreover, the fatty acid composition in the oil samples was analysed using gas chromatography–mass spectrometry. This analysis showed that the percentages of monounsaturated (46.61%), and polyunsaturated fatty acids (42.14%), after appl…

FlavonoidPharmaceutical ScienceMass spectrometry01 natural sciencesGas Chromatography-Mass SpectrometryArticleAnalytical Chemistrylcsh:QD241-4410404 agricultural biotechnologylcsh:Organic chemistryResponse surface methodologyDrug DiscoveryPlant OilsProcess optimizationPhysical and Theoretical Chemistry<i>Chaenomelessinensis</i> (Thouin) Koehne seed oil; subcritical fluid extraction; response surface methodology; fatty acid composition; polyphenol contentMicrowavesRosaceaeChaenomelessinensis (Thouin) Koehne seed oil; Fatty acid composition; Polyphenol content; Response surface methodology; Subcritical fluid extraction; Organic Chemistrychemistry.chemical_classificationChromatography010405 organic chemistryPolyphenol contentExtraction (chemistry)Organic ChemistryPilot scalePolyphenols04 agricultural and veterinary sciences040401 food scienceChaenomelessinensis (Thouin) Koehne seed oil0104 chemical scienceschemistryChemistry (miscellaneous)PolyphenolFatty Acids UnsaturatedMolecular MedicineFatty acid compositionFatty acid compositionSubcritical fluid extractionPolyunsaturated fatty acid
researchProduct

Evaluation of antioxidant properties and assessment of genetic diversity of Capparis spinosa cultivated in Pantelleria Island.

2017

Capparis spinosa is a wild and cultivated bush, which grows mainly in the Mediterranean Basin. Unopened flower buds, called capers are used in the Mediterranean cuisine as flavoring for meat, vegetable and other foods. Several studies evaluated bioactive component and antioxidant activity of Capparis spinosa, increasing the market demand and the economic importance of capers.The aim of this work was to evaluate the contents of bioactive compounds in floral buds fermented in salt of C. spinosa collected from different areas of Pantelleria Island (Italy), testing the effect on healthy function as total antioxidant compounds. Hydrophilic extracts of C. spinosa from Pantelleria Island were char…

Genetic diversityABTSBioactive componentDPPHCapparis spinosaPolyphenolsCapparis spinosa Caper antioxidant polyphenols Bioactive components HPLC-MS AFLP ABTS Folin & Ciocalteu ORAC DPPH flavonoidsMediterranean Basinfood.foodHPLC-MSSettore AGR/03 - Arboricoltura Generale E Coltivazioni Arboreechemistry.chemical_compoundHorticultureGeographyfoodchemistryCapparis SpinosaAmplified fragment length polymorphismCaperAntioxidantQuercetinFlavor
researchProduct