Search results for " Printing"

Aqueous Processed Biopolymer Interfaces for Single-Cell Microarrays

2020

Single-cell microarrays are emerging tools to unravel intrinsic diversity within complex cell populations, opening up new approaches for the in-depth understanding of highly relevant diseases. However, most of the current methods for their fabrication are based on cumbersome patterning approaches, employing organic solvents and/or expensive materials. Here, we demonstrate an unprecedented green-chemistry strategy to produce single-cell capture biochips onto glass surfaces by all-aqueous inkjet printing. At first, a chitosan film is easily inkjet printed and immobilized onto hydroxyl-rich glass surfaces by electrostatic immobilization. In turn, poly(ethylene glycol) diglycidyl ether is graft…

Droplet-to-droplet microarray for drug screening in picoliter scale

2012

Advanced Drug Screening platforms by Inkjet printing

2011

In this work, we show a low-cost, speed, microarray-based drug screening platform that employs inkjet printing drug dispensing on an enzymatic-rich surface. Mixtures of a model substrate (Dglucose)/ inhibitor (D-glucal) couple have been inkjet printed on a target enzymatic monolayer (glucose oxidase) linked to a functionalized silicon oxide solid surface [1]. It has been possible to fabricate microarrays with quality factors as high as those of conventional pin printing spotting. By a simple horseradish-based colorimetric enzymatic assay, the detection of biological activity at the single spot has been proved. The figure shows a scheme of the platform: molecular inks of the enzymatic substr…

3D-Printed Solid Dispersion Drug Products.

2019

With the well-known advantages of additive manufacturing methods such as three-dimensional (3D) printing in drug delivery, it is disappointing that only one product has been successful in achieving regulatory approval in the past few years. Further research and development is required in this area to introduce more 3D printed products into the market. Our study investigates the potential of fixed dose combination solid dispersion drug products generated via 3D printing. Two model drugs&mdash

Inkjet printing methodologies for drug screening

2010

We show for the first time a contactless, low-cost, and rapid drug screening methodology by employing inkjet printing for molecular dispensing in a microarray format. Picoliter drops containing a model substrate (D-glucose)/ inhibitor (D-glucal) couple were accurately dispensed on a single layer consisting of the enzymatic target (glucose oxidase) covalently linked to a functionalized silicon oxide support. A simple colorimetric detection method allowed one to prove the screening capability of the microarray with the possibility to assay with high reproducibility at the single spot level. Measurements of the optical signal as a function of concentration and of time verified the occurrence a…

STEAM Practices to Explore Ancient Architectures Using Augmented Reality and 3D Printing with GeoGebra

2021

Abstract In this study, we develop mathematical educational practices for students to explore ancient buildings using GeoGebra, Augmented Reality and 3D printing. It is an interdisciplinary approach, intertwining history, culture, mathematics, and engineering. For example, the 3D modelling of Cheomseongdae in Korea and the Temple of Dendera in Egypt can enable students to practice a multimodal set of traditional and innovative learning approaches. Students might use their mathematical knowledge to reflect on architectural and cultural history in a modeling task.

Sustainability for 3DP Operations

2020

Sustainability is an essential consideration in manufacturing, and within this chapter a detailed appraisal is given to sustainability for 3D printing. An in-depth review of existing research is provided, and a cradle-to-grave assessment technique is shown to assess the environmental impact of 3D printed part.

Ergonomic Risks in the Printing Company and Workers’ Wellbeing

2014

The aim of the study was to analyze the ergonomic risks in the printing company and to study the impact of ergonomics risks on employees’ wellbeing. The study involved 67 company workers aged 18 to 67 years. In the study, physical load evaluation methods and questionnaire on welfare and psychoemotional risks at work, adopted by Swedish Environmental Research Institute, were used. It was proved that production workers were subjected to increased physical workload. At work they are exposed to physical pressure on hands, shoulders and back. The workload is more affected by the increase in work tension due to limited time of order execution. It was concluded that ergonomic risks partly affect e…

Selective recovery of gold from electronic waste using 3D-printed scavenger

2017

Around 10% of the worldwide annual production of gold is used for manufacturing of electronic devices. According to the European Commission, waste electric and electronic equipment is the fastest growing waste stream in the European Union. This has generated the need for an effective method to recover gold from electronic waste. Here, we report a simple, effective, and highly selective nylon-12-based three-dimensional (3D)-printed scavenger objects for gold recovery directly from an aqua regia extract of a printed circuit board waste. Using the easy to handle and reusable 3D-printed meshes or columns, gold can be selectively captured both in a batch and continuous flow processes by dipping …

Pseudoisochromatic test plate colour representation dependence on printing technology

2012

The aim of the study is to determine best printing technology for creation of colour vision deficiency tests. Valid tests for protanopia and deuteranopia were created from perceived colour matching experiments from printed colour samples by colour deficient individuals. Calibrated EpsonStylus Pro 7800 printer for ink prints and Noritsu HD 3701 digital printer for photographic prints were used. Multispectral imagery (by tunable liquid crystal filters system CRI Nuance Vis 07) data analysis show that in case of ink prints, the measured pixel colour coordinate dispersion (in the CIExy colour diagram) of similar colour arrays is smaller than in case of photographic printing. The print quality i…