Search results for " Program"
showing 10 items of 3075 documents
E-Learning in Pharmacology and Pharmacy
2011
Computer-based learning facilitates a shift from externally controlled to self-directed learning. Universities and other educational institutions are challenged by these developments and must react appropriately to meet the requirements of education. The term e-learning has been coined to describe a wide range of diverse learning and teaching strategies based on the use of electronic devices. Recently developed concepts in the science of education and learning provide appropriate frameworks for novel e-learning scenarios. The present review introduces strategies and concepts for the implementation of e-learning in academic and non-academic programs and gives an overview of current e-learnin…
Prescription drug use during pregnancy in France: a study from the national health insurance permanent sample.
2017
International audience; PurposeTo provide an up-to-date account of drug prescription during pregnancy in France from 2011 to 2014 using the permanent sample of the French national computerized healthcare database and with a focus on recommended supplementations, fetotoxic drugs and teratogenic drugs.MethodsAll pregnancies identified by the International Classification of Diseases, 10th Revision codes list in the hospitalization database, lasting more than 9 weeks of amenorrhea and whose delivery occurred between 01/01/2011 and 12/31/2014, were included. Drugs delivered between the trimester before and until the end of the pregnancy were included. Drug exposure prevalence was calculated for …
The embodiment of wastewater data for the estimation of illicit drug consumption in Spain
2021
Data obtained from wastewater analysis can provide rapid and complementary insights in illicit drug consumption at community level. Within Europe, Spain is an important country of transit of both cocaine and cannabis. The quantity of seized drugs and prevalence of their use rank Spain at the top of Europe. Hence, the implementation of a wastewater monitoring program at national level would help to get better understanding of spatial differences and trends in use of illicit drugs. In this study, a national wastewater campaign was performed for the first time to get more insight on the consumption of illicit drugs within Spain. The 13 Spanish cities monitored cover approximately 6 million inh…
Cognitive Frailty: An Update
2021
This review article provides an update of the empirical research on cognitive fragility conducted in the last four years. The studies retrieved were classified in four different categories. The first category includes articles relating cognitive frailty to cognitive reserve and which continue to highlight the importance of educational level. The second category includes recent research on cognitive fragility biomarkers, involving neuroimaging, metabolism and, in a novel way, microbiota. The third category includes research on how cognitive frailty is related to motor development and physical functioning, exploring e.g. the use of technology to study motor markers of cognitive frailty. Final…
Valutazione sperimentale della durabilità di intonaci finalizzata alla manutenzione programmata
2010
La Legge 109/94 ha imposto per i nuovi interventi pubblici, la programmazione della manutenzione da redigersi in fase di progettazione esecutiva. La fase di gestione del bene edilizio assume, infatti, un’importanza strategica, nell’ottica di una ragionevole durata di vita utile espletata in un equilibrato rapporto qualità-costo globale, per la sostenibilità dell’intervento. Un contributo in tal senso è costituito dal contenimento nel consumo di risorse e di materie prime conseguibile attraverso il miglioramento del requisito di durabilità dell’edificio e delle sue parti, cosa possibile se si conosce il comportamento nel tempo di componenti e sistemi edilizi contestualizzati. Ciò vale anche …
Impulsively-controlled systems and reverse dwell time: A linear programming approach
2015
We present a receding horizon algorithm that converges to the exact solution in polynomial time for a class of optimal impulse control problems with uniformly distributed impulse instants and governed by so-called reverse dwell time conditions. The cost has two separate terms, one depending on time and the second monotonically decreasing on the state norm. The obtained results have both theoretical and practical relevance. From a theoretical perspective we prove certain geometrical properties of the discrete set of feasible solutions. From a practical standpoint, such properties reduce the computational burden and speed up the search for the optimum thus making the algorithm suitable for th…
Quantized Dissensus in Networks of Agents subject to Death and Duplication
2012
Dissensus is a modeling framework for networks of dynamic agents in competition for scarce resources. Originally inspired by biological cells behaviors, it fits also marketing, finance and many other application areas. Competition is often unstable in the sense that strong agents, those having access to large resources, gain more and more resources at the expense of weak agents. Thus, strong agents duplicate when reaching a critical amount of resources, whereas weak agents die when loosing all their resources. To capture all these phenomena we introduce systems with a discrete time gossip and unstable state dynamics interrupted by discrete events affecting the network topology. Invariancy o…
Optimal Usage of Multiple Network Connections
2008
In the future mobile networks, a mobile terminal is able to select the best suitable network for each data transmission. The selection of a network connection to be used has been under a lot of study. In this paper, we consider a more extensive case in which we do not select a network connection but use several network connections simultaneously to transfer data. When data is transferred using multiple network connections, a network connection has to be selected for each component of the data. We have modelled this problem as a multiobjective optimization problem and developed a heuristic to solve the problem fast in a static network environment. In this paper, we discuss solving the proble…
Inferring slowly-changing dynamic gene-regulatory networks
2015
Dynamic gene-regulatory networks are complex since the interaction patterns between their components mean that it is impossible to study parts of the network in separation. This holistic character of gene-regulatory networks poses a real challenge to any type of modelling. Graphical models are a class of models that connect the network with a conditional independence relationships between random variables. By interpreting these random variables as gene activities and the conditional independence relationships as functional non-relatedness, graphical models have been used to describe gene-regulatory networks. Whereas the literature has been focused on static networks, most time-course experi…
Swing options in commodity markets: a multidimensional Lévy diffusion model
2013
Author's version of an article in the journal: Mathematical Methods of Operations Research. Also available from the publisher at: http://dx.doi.org/10.1007/s00186-013-0452-7 We study valuation of swing options on commodity markets when the commodity prices are driven by multiple factors. The factors are modeled as diffusion processes driven by a multidimensional Lévy process. We set up a valuation model in terms of a dynamic programming problem where the option can be exercised continuously in time. Here, the number of swing rights is given by a total volume constraint. We analyze some general properties of the model and study the solution by analyzing the associated HJB-equation. Furthermo…