Search results for " REM"

The nucleosome remodeling factor ISWI functionally interacts with an evolutionarily conserved network of cellular factors

2010

Abstract ISWI is an evolutionarily conserved ATP-dependent chromatin remodeling factor playing central roles in DNA replication, RNA transcription, and chromosome organization. The variety of biological functions dependent on ISWI suggests that its activity could be highly regulated. Our group has previously isolated and characterized new cellular activities that positively regulate ISWI in Drosophila melanogaster. To identify factors that antagonize ISWI activity we developed a novel in vivo eye-based assay to screen for genetic suppressors of ISWI. Our screen revealed that ISWI interacts with an evolutionarily conserved network of cellular and nuclear factors that escaped previous genetic…

Chromatin remodeling redulation by small molecules and metabolites

2010

Isovaleraldehyde degradation using UV photocatalytic and dielectric barrier discharge reactors, and their combinations

2015

International audience; The abatement of isovaleraldehyde present in air was carried out in UV photocatalytic and dielectric barrier discharge reactors (and their combinations) for concentrations up to 150 mg C m−3 and air flow rates ranging from 4 to 10 m3 h−1. A kinetic study was performed following a Langmuir–Hinshelwood model. Photocatalytic treatment of an isovaleraldehyde and isovaleric acid mixture showed a clear inhibition of isovaleric acid abatement in presence of isovaleraldehyde. Dielectric barrier discharge treatment of isovaleraldehyde showed an increase of removal efficiency with applied voltage and a decrease with air flow rate and inlet concentration. Moreover, introduction…

Cultivation of granular sludge with hypersaline oily wastewater

2015

The time required to stabilise mature aerobic granules is rather variable. In addition, cultivation time and the structural characteristics of granules seem to be related to the nature of wastewater influent. Granular sludge has been used for the treatment of several industrial wastewaters, but nothing has been reported about wastewater characterized by the simultaneous presence of hydrocarbons and high chloride concentration. In this work, the authors analysed the granulation process and performance as well as the physical characteristics of aerobic granules in two Granular Sequencing Batch Airlift Reactors (GSBARs), fed with acetate-based synthetic wastewater in reactor 1 (R1) and with a …

ORGANIZATION OF HIGHER-LEVEL CHROMATIN STRUCTURES (CHROMOMERE, CHROMONEMA AND CHROMATIN BLOCK) EXAMINED USING VISIBLE LIGHT-INDUCED CHROMATIN PHOTO-S…

2002

The method of chromatin photo-stabilization by the action of visible light in the presence of ethidium bromide was used for investigation of higher-level chromatin structures in isolated nuclei. As a model we used rat hepatocyte nuclei isolated in buffers which stabilized or destabilized nuclear matrix. Several higher-level chromatin structures were visualized: 100 nm globules—chromomeres, chains of chromomeres—chromonemata, aggregates of chromomeres—blocks of condensed chromatin. All these structures were completely destroyed by 2 M NaCl extraction independent of the matrix state, and DNA was extruded from the residual nuclei (nuclear matrices) into a halo. These results show that nuclear …

Detailed study of SNR G306.3–0.9 using XMM-Newton and Chandra observations

2016

Aims. We aim to study the spatial distribution of the physical and chemical properties of the X-ray emitting plasma of the supernova remnant (SNR) G306.3-0.9 in detail to obtain constraints on its ionization stage, the progenitor supernova explosion, and the age of the remnant. Methods. We used combined data from XMM-Newton and Chandra observatories to study the X-ray morphology of G306.3-0.9 in detail. A spatially resolved spectral analysis was used to obtain physical and geometrical parameters of different regions of the remnant. Spitzer infrared observations, available in the archive, were also used to constrain the progenitor supernova and study the environment in which the remnant evol…

SHOCK-CLOUD INTERACTION AND PARTICLE ACCELERATION IN THE SOUTHWESTERN LIMB OF SN 1006

2014

The supernova remnant SN 1006 is a powerful source of high-energy particles and evolves in a relatively tenuous and uniform environment despite interacting with an atomic cloud in its northwestern limb. The X-ray image of SN 1006 reveals an indentation in the southwestern part of the shock front and the H I maps show an isolated (southwestern) cloud, having the same velocity as the northwestern cloud, whose morphology fits perfectly in the indentation. We performed spatially resolved spectral analysis of a set of small regions in the southwestern nonthermal limb and studied the deep X-ray spectra obtained within the XMM-Newton SN 1006 Large Program. We also analyzed archive H I data, obtain…

NEMATODE COLONIZATION OF PYRITE CINDER-POLLUTED SOIL

2020

The nematofauna was studied in the early stages of a remediation trial at an industrial site where pyrite cinders had accumulated for 40 years in a large area and were then covered with mineral soil. The cinders were contaminated with several metals and metalloids. The soil of the experimental plots was derived from the mixture of cinders with the covering soil in a 1:1 ratio. Plots were amended with manure and sown with 3 metal resistant plants: Sorghum bicolor L., Helianthus annuus L., and Arundo donax L. Samples were taken : a) at the beginning of the trial on the pyrite cinders and covering soil, separately; b) from the mixture before the application of manure; c) from cultivated plots.…

Prediction of soil texture distributions using VNIR-SWIR reflectance spectroscopy

2013

Abstract Reflectance spectroscopy provides an alternate method to non-destructively characterize key soil properties. Different approaches, including chemometrics techniques or specific absorption features, have been proposed to estimate soil properties from visible and near-infrared (VNIR, 400-1200 nm) and shortwave infrared (SWIR, 1200-2500 nm) reflectance domains. The main goal of this study was to test the performance of two distinct methods for soil texture estimation by VNIR-SWIR reflectance measurements: i) the Continuum Removal (CR) technique that was used to correlate specific spectral absorption features with clay, silt and sand content, and ii) the Partial Least-Squares Regressio…

Cognitive impairment in relapsing-remitting multiple sclerosis can be predicted by imaging performed several years earlier.

2007

Cognitive deficits in multiple sclerosis (MS) are common and correlate with contemporary MRI brain abnormalities, particularly atrophy, but the ability of imaging early in the disease to predict later cognitive impairment remains to be determined. Thirty relapsing—remitting MS patients recruited within three years of the onset of the disease, and in whom MRI had been performed at baseline and a year later, were assessed neuropsychologically five years later. Imaging parameters accounting for significant variance in cognitive performance were identified using multiple regressions, once confounding variables were controlled. Patients performed significantly worse than expected on tests of at…