Search results for " Radioterapia"
showing 10 items of 552 documents
Whole-body diffusion weighted MR and FDG-PET/CT in Hodgkin lymphoma: predictive role before treatment and early assessment aftrer two courses of chem…
2017
To evaluate whether whole-body MR has a predictive role before treatment and may asses the response after two courses of chemotherapy in comparison to FDG-PET/CT
ROLE OF ENDOVASCULAR EMBOLIZATION IN THE MULTIDISCIPLINARY MANAGEMENT OF RUPTURED BRAIN ARTERIOVENOUS MALFORMATIONS
2022
Brain arteriovenous malformations (bAVMs) are congenital defects of vasculogenesis, the natural history of which is characterized by a significant morbidity and mortality related to the risk of bleeding. Their management remains challenging, since complete eradication is often difficult. Embolization, surgery, or radiosurgery alone are safe and effective for small unruptured AVMs, while a multidisciplinary approach should be pursued for larger ones. We report a case of intracerebral haemorrhage due to the rupture of a large bAVM, for which a multidisciplinary approach was adopted: endovascular partial embolization followed by complete surgical removal.
MRI Characterization of non-Gaussian water diffusion in the brain using Diffusion Kurtosis Imaging (DKI)
2016
Diffusion tensor imaging (DTI) is the most commonly used technique to extract microstructural features from a set of diffusion-weighted images. In addition to the metrics obtained with DTI, diffusion kurtosis imaging (DKI) can provide non-Gaussian diffusion measures by means of the kurtosis tensor. DKI give an dimensionless measure that quantifies the deviation of the water diffusion displacement profile from the Gaussian distribution of unrestricted diffusion, providing a measure of the degree of diffusion hindrance or restriction. DKI has shown to be more sensitive to tissue microstructural changes in both normal and pathological neural tissue. The aim of this work is the description of t…
Functional connectivity modulation induced by transcranial direct current stimulation of the motor network: a Resting-State fMRI study
2016
Resting-state functional connectivity represents a novel fMRI approach that allows detection of temporal correlations in spontaneous BOLD signal oscillations while subjects rest quietly in the scanner. Functional connectivity (FC) can be defined as the synchrony of neural activity among spatially distant regions. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that is known to modulate cortical activity and FC among brain regions. This study is aimed at measuring the variation of functional connectivity between cortical brain regions after tDCS along time. The temporal concatenation group ICA showed that immediately after anodal stimulation the a…
Long-lasting coma.
2014
n this report, we describe the case of a patient who has remained in a comatose state for more than one year after a traumatic and hypoxic brain injury. This state, which we refer to as long-lasting coma (LLC), may be a disorder of consciousness with significantly different features from those of conventional coma, the vegeta- tive state, or brain death. On the basis of clinical, neu- rophysiological and neuroimaging data, we hypothe- size that a multilevel involvement of the ascending reticular activating system is required in LLC. This description may be useful for the identification of other patients suffering from this severe disorder of con- sciousness, which raises important ethical i…
Le cefalee: reperti diagnostici nell’adulto
2019
Sessioen young topics "Le Cefalee": Reperti diagnostici nell’adulto
Radiographic Features with Pathological Correlation in Cerebral Amyloid Inflammatory Vasculopathy A Case Report
2014
Cerebral Amyloid Angiopathy (CAA) is characterized by deposit of β-amyloid protein in the cortical and leptomeningeal arteries. It tends to increase in prevalence with advancing age and seems to have slight predilection for temporal, parietal and occipital lobes. It has recently been identified an inflammatory form of this angiophaty. This report describes a case presenting as an inflammatory vasculitis-perivasculitis form successfully treated with steroids and discuss about typical features and findings of this condition.
Encefalopatia ipertensiva cronica (EIC): sensibilità delle sequenze GE-T2* a confronto con le SWI nell'identificazione dei micro-sanguinamenti
2014
L'EIC è caratterizzata dalla presenza di lesioni parenchimali irreversibili, risultato di una lunga esposizione a regimi pressori patologici specie in pazienti che non seguono o non rispondono alle comuni terapie mediche. Si riscontrano quali reperti tipici multipli esiti gliotici, leucoaraiosi e multiple lesioni lacunari con predilezione per le localizzazioni profonde ai nuclei lenticolari, ai talami e al ponte. Più raramente possono evidenziarsi minuti foci emorragici parenchimali, più frequentemente localizzati nei gangli della base ma anche nel ponte e nel cervelletto, che in alcuni casi possono rappresentare la manifestazione principale della patologia: questi microsanguinamenti, vi…
Thalamic parcellation for target identification in trans-cranial MR-guided Focused UltraSound (tcMRgFUS) thalamotomies: a preliminary probabilistc tr…
2018
Background: Trans-cranial MR-guided Focused UltraSound (tcMRgFUS) allows a neurofunctional exploration of thalamic nuclei to confirm and optimize the target before inducing a permanent brain lesion. However, the choice of the target is based on stereotactic coordinates that do not take into account the anatomical variability of each single patient. Thus, the optimization of the treatment target is based on the patient's feedback during lower power sonications. The aim of this work is to retrospectively evaluate the possible role of thalamic parcellation for the identification of the intermediate ventral nucleus (VIM) in patients undergoing tcMRgFUS. Materials and Methods: A 1.5T MR scanner …
Terapia trans-cranica ad ultrasuoni focalizzati guidati da Risonanza Magnetica (tcMRgFUS): studio di parcellizzazione talamica per l'identificazione …
2018
Scopo La tcMRgFUS consente di effettuare una vera e propria esplorazione neurofunzionale per confermare ed ottimizzare il target lesionale prima di indurre una lesione cerebrale permanete. La scelta del target di trattamento si basa tuttavia su coordinate stereotassiche che non tengono conto delle diversità anatomiche di ciascun individuo. L'ottimizzazione del target viene effettuata sulla base del feedback del paziente durante la procedura stessa. Scopo di questo lavoro è valutare il possibile ruolo della parcellizzazione talamica per l'identificazione del nucleo ventrale intermedio (VIM) in pazienti sottoposti a tcMRgFUS. Materiali e metodi È’ stato utilizzato uno scanner RM da 1,5T per a…